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MSDS 
:
 Erythrosin B, high purity biological stain
CAS 
:
 16423-68-0
SYNONYMS 
:
 Acid Red 51; C.I. 45430;     9-(o-Carboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H-xanthene-3-one     disodium salt; Disodium     2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate;     Fluorescein, 2',4',5',7'-tetraiodo-, disodium salt;     Tetraiodofluorescein sodium salt
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 16423-68-0 |Erythrosin B, high purity biological s| 100 | 240-474-8 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 22

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Harmful if swallowed.Hygroscopic (absorbs moisture from the air).

Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May be harmful if swallowed. May cause thyroid
abnormalities.
Inhalation:
May cause respiratory tract irritation.
Chronic:
May cause thyroid abnormalities.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid immediately. Do NOT induce vomiting. If conscious and alert,
rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Provide ventilation.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Avoid contact with
eyes, skin, and clothing. Keep container tightly closed. Do not
ingest or inhale. Keep from contact with moist air and steam. Do not
breathe dust.
Storage:
Keep container closed when not in use. Store protected from
moisture. Store in a cool, dry area away from incompatible
substances.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use process enclosure,
local exhaust ventilation, or other engineering controls to control
airborne levels.
Exposure Limits
CAS# 16423-68-0:


Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Powder
Color: dark red
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: soluble
Specific Gravity/Density: Not available.
Molecular Formula: C20H6I4Na2O5
Molecular Weight: 879.85

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants, exposure to moist air or
water.
Incompatibilities with Other Materials:
Moisture, strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen iodide, iodide, sodium monoxide.
Hazardous Polymerization: Has not been reported.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 16423-68-0: LM5950000
LD50/LC50:
CAS# 16423-68-0: Oral, mouse: LD50 = 1264 mg/kg; Oral, rat: LD50 =
1840 mg/kg.
Carcinogenicity:
Erythrosin B, high purity biological stain -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****



**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 16423-68-0: 1
Canada
CAS# 16423-68-0 is listed on Canada's DSL List.
CAS# 16423-68-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 16423-68-0 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

MSDS Creation Date: 9/02/1997 Revision #5 Date: 3/18/2003

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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