*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : VV9100000
CHEMICAL NAME : Silicic acid, beryllium zinc salt
CAS REGISTRY NUMBER : 39413-47-3
OTHER CAS REGISTRY NOS. : 63089-82-7
LAST UPDATED : 199712
DATA ITEMS CITED : 43
WISWESSER LINE NOTATION : BE ZN SI-O4
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Beryllium zinc silicate
* Zinc beryllium silicate
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg/kg/2W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Musculoskeletal - tumors
REFERENCE :
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823-
Volume(issue)/page/year: 1,519,1950
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Musculoskeletal - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year:
20,778,1966
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 17 mg(Be)/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Musculoskeletal - tumors
Tumorigenic - tumors at site of application
REFERENCE :
BUCABS Bulletin du Cancer. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53-
1966- Volume(issue)/page/year: 62,49,1975
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Musculoskeletal - tumors
REFERENCE :
ARPAAQ Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50;
V.70-99, 1960-75. For publisher information, see APLMAS.
Volume(issue)/page/year: 88,89,1969
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/kg/10W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Musculoskeletal - tumors
REFERENCE :
JBSUAK Journal of Bone and Joint Surgery, British Volume. (10 Shattuck St.,
Boston, MA 02115) V.30- 1948- Volume(issue)/page/year: 36,543,1954
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/kg/6W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Musculoskeletal - tumors
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 5,221,1946
*** REVIEWS ***
ACGIH TLV-SUSPECTED HUMAN CARCINOGEN
85INA8 "Documentation of the Threshold Limit Values and Biological Exposure
Indices," 5th ed., Cincinnati, OH, American Conference of Governmental
Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,1/BEI,1997
ACGIH TLV-TWA 0.002 mg(Be)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-Suspected human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 1,17,1972
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 23,143,1980
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,41,1993
IARC Cancer Review:Human Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,41,1993
IARC Cancer Review:Group 1
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,41,1993
TOXICOLOGY REVIEW
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 9,105,1971
*** U.S. STANDARDS AND REGULATIONS ***
OSHA PEL (Gen Indu):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-ARAB Republic of Egypt:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-AUSTRALIA:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-BELGIUM:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-DENMARK:TWA 0.001 mg(Be)/m3;Carcinogen JAN 1993
OEL-FINLAND:TWA 0.002 mg(Be)/m3;STEL 0.006 mg(Be)/m3;Carcinogen JAN 1993
OEL-FRANCE:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-GERMANY;Carcinogen JAN 1993
OEL-HUNGARY:STEL 0.001 mg(Be)/m3;Carcinogen JAN 1993
OEL-INDIA:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-JAPAN:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-THE NETHERLANDS:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-POLAND:TWA 0.001 mg(Be)/m3 JAN 1993
OEL-RUSSIA:STEL 0.001 mg(Be)/m3;Carcinogen JAN 1993
OEL-SWEDEN:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-SWITZERLAND:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-THAILAND:TWA 0.002 mg(Be)/m3;STEL 0.005 mg(Be)/m3 JAN 1993
OEL-TURKEY:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.002 mg(Be)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO BERYLLIUM-air:CA not to exceed 0.0005 mg(Be)/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
NTP 7th Annual Report on Carcinogens, 1992 : anticipated to be carcinogen
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Silicate, soapstoneSUBSTANCE DEFINITION :Containing less than 1% crystalline silicaREFERENCE :FEREAC Federal Register. (U.S. Government Printing Office, Supt. ofDocuments, Washington, DC 20402) V.1- 1936-
| 65997-15-1 |
Silicic acid
| 7699-41-4 |
Silicic acid (ortho)
| 10193-36-9 |
Silicic acid (polyortho)
| 1343-98-2 |
Silicic acid, aluminum magnesium salt
| 1327-43-1 |
Silicic acid, beryllium salt
| 15191-85-2 |
Silicic acid, beryllium zinc salt
| 39413-47-3 |
SF-1508
| 56378-68-8 |
Silicic acid, calcium salt
| 1344-95-2 |
Silicic acid (H2SiO3), calcium salt (11)
| 10101-39-0 |
Silicic acid, 2-chloroethyl ester
| 10101-39-0 |
Silicic acid (H2SiO3), disodium salt
| 6834-92-0 |
Silicic acid, 2-ethylbutyl ester
| 68037-57-0 |
Silicic acid, methyl ester
| 12002-26-5 |
Silicic acid, tetra(2-ethylbutyl) ester
| 78-13-7 |
Silicic acid, tetraethyl ester
| 78-10-4 |
Silicic acid, tetra(2-fluoroethyl) ester
| 650-00-0 |
Silicic acid, tetrakis(2-chloroethyl) ester
| 18290-84-1 |
SF-1739
| 61991-01-3 |
Silicic acid (H2SiO4), tetrakis(1-methylpropyl) ester
| 5089-76-9 |
Silicic acid, tetramethyl ester
| 681-84-5 |
Silicon
| 7440-21-3 |
Silicon(1+),(1-(bis(2-hydroxyethyl)amino)-2-propanolato(3-)-N,O,O',O") (ethylmethylsulfonium eta-methylide)-, iodide,(TB-5-34)-
| 67349-10-4 |
Silicon carbide
| 409-21-2 |
Silicon chloride
| 10026-04-7 |
Silicon chrome
| 11133-78-1 |
Silicon(1+), (diethylsulfoniumeta-methylide)((1,1',1"-nitrilotris(2-propanolato))(3-)- N,O,O',O")-, bromide, (TB-5-23)
| 67366-36-3 |
Silicon(1+), ((1,1-dimethylethyl)methylsulfoniumeta-methylide)((2,2',2"-nitrilotris(ethanolato))(3-)-N,O,O',O")-, iodide, (TB-5-23)-
| 67349-11-5 |
Silicon dioxide, hydrate
| 67349-11-5 |
SF 3024-B20-KOSUBSTANCE DEFINITION :Phenol resin which is mixture of oligomersREFERENCE :GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene andOccupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)V.1-36, 1957-1992. For publisher information, see MTPEEIVolume(issue)/page/year: 28(7),53,1984
| 67349-11-5 |
Silicon,(3,3,4,4,5,5,6,6,7,7,8,8-dodecafluoro-1-iodooctyl)((2,2'2,''-nitrilotris(e thanolato))(3-)-N,O,O',O'')-,(TB-5-23)-
| 135798-16-2 |
Silicon,(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-iododecyl)((2,2',2 ''-nitrilotris(ethanolato(3-)-N,O,O',O'')-, (TB-5-23)-
| 135798-18-4 |
Silicon,(3,3,4,4,5,5,5-heptafluoro-1-iodopentyl)((2,2',2''-nitrilotris(ethanolato) )(3-)- N,O,O',O'')-, (TB-5-23)-
| 112341-58-9 |
Silicon,(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-hexadecafluoro-1-iododecyl)((2,2',2''-n itrilotris(ethanolato))(3-)-N,O,O',O'')-, (TB-5-23)-
| 135798-17-3 |
Silicon,((2,2',2''-nitrilotris(ethanolato))(3-)-N,O,O',O'')(3,3,4,4,5,5,6,6,6-nona fluoro-1- iodohexyl)-,(TB-5-23)-
| 135798-15-1 |
Silicon,((2,2',2''-nitrilotris(ethanolato))(3-)-N,O,O',O'')(3,3,4,4,5,5,6,6-octafl uoro-1- iodohexyl)-, (TB-5-23)-
| 135798-14-0 |
Silicon,((2,2',2''-nitrilotris(ethanolato))(3-)-N,O,O',O'')(3,3,4,4,5,5,6,6,7,7,8, 8,8-tridecafluoro-1-iodooctyl)-, (TB-5-23)-
| 135829-02-6 |
Silicon,((2,2',2''-nitrilotris(ethanolato))(3-)-N,O,O',O'')(3,3,3-trifluoro-1-iodo propyl)-, (TB-5-23)-
| 112341-57-8 |
Silicone 7158
| 112341-57-8 |
Silicone antifoam sag-47
| 112341-57-8 |
SF-1540 A
| 71329-58-3 |
Silicone antifoam sag-100
| 71329-58-3 |
Silicone C-25
| 71329-58-3 |
Silicone fluid L-43
| 71329-58-3 |
Silicone L-31
| 71329-58-3 |
Silicone L-42 (oil)
| 71329-58-3 |
Silicone L-45
| 63148-62-9 |
Silicone L-75
| 63148-53-8 |
Silicone L-76
| 63148-53-8 |
Silicone L-77
| 63148-53-8 |
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