*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CI6476000
CHEMICAL NAME : Asbestos, actinolite
CAS REGISTRY NUMBER : 77536-66-4
LAST UPDATED : 199712
DATA ITEMS CITED : 17
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* Actinolite asbestos
* Asbestos
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
REFERENCE :
STRHAV Staub-Reinhaltung der Luft. (VDI-Verlag GmbH, Postfach 1139, D-4000
Duesseldorf 1, Fed. Rep. Ger.) V.26- 1966- Volume(issue)/page/year:
39,386,1979
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 200 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
REFERENCE :
STRHAV Staub-Reinhaltung der Luft. (VDI-Verlag GmbH, Postfach 1139, D-4000
Duesseldorf 1, Fed. Rep. Ger.) V.26- 1966- Volume(issue)/page/year:
39,386,1979
*** REVIEWS ***
ACGIH TLV-Confirmed human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 2 fibers/cc
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 14,11,1977
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 2,17,1973
IARC Cancer Review:Human Sufficient Evidence
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,106,1987
IARC Cancer Review:Group 1
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,106,1987
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 5 fb/cc (fb > 5 um)
DTLWS* "Documentation of the Threshold Limit Values for Substances in
Workroom Air," Supplements. For publisher information, see 85INA8.
Volume(issue)/page/year: 3,33,1973
OSHA-cancer hazard
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1001,1987
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-SWITZERLAND:TWA 1 fiber/ml;Carcinogen JAN 1993
OEL-UNITED KINGDOM:TWA 0.5 fiber/ml/4H JAN 1993
OEL-UNITED KINGDOM:TWA 1.5 fiber/ml/10M JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO ASBESTOS-air:100M TWA 0.1 fb/cc in a 400L air sample
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** STATUS IN U.S. ***
NIOSH Analytical Method, 1994: Asbestos (bulk) by PLM, 9002; by PCM, 7400;
by TEM, 7402
*** END OF RECORD ***
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Ascomycin
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L-Ascorbic acid, 2-hydrogensulfate (ester)
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Ascorbic acid, L- and L-tryptophan, reaction mixture
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Ascosin
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Ascosin A
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Ascosin B
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