*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : YJ7700000
CHEMICAL NAME : Trioctanoin
CAS REGISTRY NUMBER : 538-23-8
BEILSTEIN REFERENCE NO. : 1717202
REFERENCE : 4-02-00-00991 (Beilstein Handbook Reference)
LAST UPDATED : 199706
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C27-H50-O6
MOLECULAR WEIGHT : 470.77
WISWESSER LINE NOTATION : 7VO1YOV7&1OV7
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Caprylic acid triglyceride
* Glycerol tricaprylate
* Glycerol trioctanoate
* Glyceryl trioctanoate
* Octanoic acid, 1,2,3-propanetriyl ester
* Octanoic acid triglyceride
* Octanoin, tri-
* Panacete 800
* Rato
* Sefsol 800
* Tricaprylic glyceride
* Tricaprylin
* Trioctanoylglycerol
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 33300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >27800 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >27800 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 29600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >27800 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >27800 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3700 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity
REFERENCE :
APSCAX Acta Physiologica Scandinavica. (Karolinska Institutet, S-10401
Stockholm, Sweden) V.1- 1940- Volume(issue)/page/year: 40,338,1957
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1860 mg/kg/31D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in bladder weight
Related to Chronic Data - death
Related to Chronic Data - changes in testicular weight
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4368 mg/kg/26W-I
TOXIC EFFECTS :
Liver - other changes
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Related to Chronic Data - death
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,871,1970
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2600 mL/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Gastrointestinal - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-426,1994
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 250 gm/kg
SEX/DURATION : female 7 day(s) pre-mating - 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
alive at weaning per # alive at day 4)
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 3,180,1972
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7437
No. of Facilities: 16 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 1430 (estimated)
No. of Female Employees: 996 (estimated)
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Inconclusive: Mouse spot test
EPA TSCA Section 8(b) CHEMICAL INVENTORY
NTP Carcinogenesis studies (gavage)
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-426,94
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
1H-v-Triazolo(4,5-d)pyrimidine-5,7(4H,6H)-dione,1,4-dimethyl-
| 1632-29-7 |
Trifolium pratense Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family LeguminosaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
| 1632-29-7 |
Trifolium resupinatum Linn., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family FabaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 1632-29-7 |
Trigermoxane, 1,1,3,3,5,5-hexabutyl-
| 1632-29-7 |
Trigonella foenum-graecum Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family LeguminosaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 1632-29-7 |
Trigonella pubescence Edgew. ex. Baker, extractSUBSTANCE DEFINITION :Plant belonging to the family LeguminosaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 18,594,1980
| 1632-29-7 |
Trigonelline
| 535-83-1 |
Trigonostemon semperflorens (Roxb.)Muell.-Arg.,extractSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 535-83-1 |
Trigonostemon viridissimus (Kurz)Airy Shaw, extractSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 535-83-1 |
Trigonotis rotundifolia (DC.) Cl., extractSUBSTANCE DEFINITION :Plant belonging to the family BoraginaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 535-83-1 |
Trignostemon aurantiacus Kurz., ex Bord var.rubriflorus Balkr.& Chakravorty, extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 535-83-1 |
3H-v-Triazolo(4,5-d)pyrimidine-5,7(4H,6H)-dione,3,6-dimethyl-
| 2278-14-0 |
Triheptylamine, 6,6',6''-trimethyl-
| 2757-28-0 |
Triisobutylene oxide (Obs.)
| 68955-06-6 |
Trillium govanianum Wall., extractSUBSTANCE DEFINITION :Plant belonging to the family LiliaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 68955-06-6 |
Trimethylamine, 1-cyclohexyl-
| 16607-80-0 |
Trimethylamine, (1,2-dicarbaundecaboran(11)-1-yl)-
| 55892-33-6 |
Trimethylamine, hydrate
| 15875-97-5 |
Trimethylamine, hydrochloride
| 593-81-7 |
Trimethylamine, compd. with iodoborane (11)
| 25741-81-5 |
Trimethylamine oxide, dihydrate
| 62637-93-8 |
Trimethylenediamine, N,N'-bis(o-chlorobenzyl)-,dihydrochloride
| 2056-19-1 |
1H-v-Triazolo(4,5-d)pyrimidine-5,7(4H,6H)-dione,4,6-dimethyl-
| 2278-15-1 |
1,3-Trimethylenedinitrile
| 544-13-8 |
Trimethylene sulfoxide
| 13153-11-2 |
Tri-miltoxSUBSTANCE DEFINITION :Composed of mancozeb plus copper oxychloride, copper sulfate and coppercarbonateREFERENCE :FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave.,Willoughy, OH 44094) Volume(issue)/page/year: -,C314,1991
| 13153-11-2 |
Trinaphthyleno(5,6-bcd)furan-3,7,13-trisulfonic acid,11,16-dihydro-10,17-dihydroxy-11,16- dioxo-,trisodium salt
| 13153-11-2 |
Trioctanoin
| 538-23-8 |
Triol-700 (Obs.)
| 538-23-8 |
Triol-1500 (Obs.)
| 538-23-8 |
Trionyx sinesis polysaccharides
| 538-23-8 |
Trioside
| 538-23-8 |
Triostin
| 12795-78-7 |
3H-v-Triazolo(4,5-d)pyrimidine-5,7(4H,6H)-dione,4-hydroxy-
| 42028-33-1 |
Triostin C
| 10382-35-1 |
2,6,7-Trioxa-1-arsabicyclo(2.2.2)octane, 4-ethyl-
| 67590-56-1 |
2,6,7-Trioxa-1-arsabicyclo(2.2.2)octane, 4-isopropyl-
| 67590-57-2 |
2,6,7-Trioxa-1-arsabicyclo(2.2.2)octane, 4-methyl-
| 22223-55-8 |
2,8,9-Trioxa-5-aza-1-borabicyclo(3.3.3)undecane
| 283-56-7 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane
| 7246-81-3 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-((2-aminoethyl)thio)-, monohydrochloride
| 124186-98-7 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-((2-amino-1-methylethyl)thio)-, monohydrochloride
| 124187-00-4 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-((2-((3-aminopropyl)amino)ethyl)thio)-
| 124187-02-6 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-((2-((3-aminopropyl)amino)ethyl)thio)-,dihydrochloride
| 124187-03-7 |
3H-v-Triazolo(4,5-d)pyrimidine-5,7(4H,6H)-dione,3-(2-hydroxyethyl)-
| 2034-24-4 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-((1H-benzimidazol-1-yl)methyl)-
| 100446-93-3 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-(bromomethyl)-
| 100446-86-4 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)-
| 100446-92-2 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane-1-ethanamine
| 91023-00-6 |
2,8,9-Trioxa-5-aza-1-germabicyclo(3.3.3)undecane,1-ethenyl-
| 76211-47-7 |
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