RTECS NUMBER : YR1450000
CHEMICAL NAME : Uracil, 1-beta-D-ribofuranosyl-
CAS REGISTRY NUMBER : 58-96-8
LAST UPDATED : 199701
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C9-H12-N2-O6
MOLECULAR WEIGHT : 244.23
COMPOUND DESCRIPTOR : Drug
Mutagen
Natural Product
SYNONYMS/TRADE NAMES :
* 1-beta-D-Ribofuranosyluracil
* Uracil riboside
* Uridin
* Uridine
* beta-Uridine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4335 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - changes in motor activity (specific assay)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 207,504,1978
** MUTATION DATA **
TYPE OF TEST : Micronucleus test
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 740 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,45,1993
TYPE OF TEST : DNA damage
TEST SYSTEM : Mammal - species unspecified Lymphocyte
DOSE/DURATION : 100 mmol/L
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States
of America. (National Academy of Sciences, Printing & Pub. Office, 2101
Constitution Ave., Washington, DC 20418) V.1- 1915-
Volume(issue)/page/year: 48,686,1962
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X1002
No. of Facilities: 35 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 115 (estimated)
No. of Female Employees: 64 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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