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MSDS  
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 Turpentine
CAS  
:
 8006-64-2
SYNONYMS  
:
 * Gum turpentine
* Gum spirits of turpentine
* Oil of turpentine
* Oil of turpentine, rectified
* Spirit of turpentine
* Spirits of turpentine
* Terebenthine
* Turpentine
* Turpentine oil
* Turpentine oil, rectifier
* Turpentine steam distilled
* Terpentin oel
* Wood turpentine

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YO8400000
CHEMICAL NAME           : Turpentine
CAS REGISTRY NUMBER     : 8006-64-2
LAST UPDATED            : 199712
DATA ITEMS CITED        : 50
COMPOUND DESCRIPTOR     : Tumorigen
                          Human
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Gum turpentine
   * Gum spirits of turpentine
   * Oil of turpentine
   * Oil of turpentine, rectified
   * Spirit of turpentine
   * Spirits of turpentine
   * Terebenthine
   * Turpentine
   * Turpentine oil
   * Turpentine oil, rectifier
   * Turpentine steam distilled
   * Terpentin oel
   * Wood turpentine
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Human
DOSE/DURATION           : 175 ppm
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 25,282,1943
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 uL
REACTION SEVERITY       : Severe
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0545856
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - infant
DOSE/DURATION           : 1748 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - nausea or vomiting
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   ADCHAK Archives of Disease in Childhood.  (British Medical Journal, POB
   560B, Kennebunkport, ME 04046)  V.1-    1926-  Volume(issue)/page/year:
   28,475,1953
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - infant
DOSE/DURATION           : 874 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
REFERENCE :
   ADCHAK Archives of Disease in Childhood.  (British Medical Journal, POB
   560B, Kennebunkport, ME 04046)  V.1-    1926-  Volume(issue)/page/year:
   28,475,1953
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   ADCHAK Archives of Disease in Childhood.  (British Medical Journal, POB
   560B, Kennebunkport, ME 04046)  V.1-    1926-  Volume(issue)/page/year:
   28,475,1953
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 175 ppm
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 25,282,1943
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 6 gm/m3/3H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - hallucinations, distorted perceptions
   Behavioral - headache
REFERENCE :
   AHYGAJ Archiv fuer Hygiene.  (Munich, Fed. Rep. Ger.)  V.1-100, 1883-1928.
   For publisher information, see ZHPMAT.  Volume(issue)/page/year: 83,239,1914
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 71 uL/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - associated connective tissue
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AJEMEN American Journal of Emergency Medicine.  (WB Saunders, Philadelphia,
   PA)  V.1-    1983-  Volume(issue)/page/year: 4,543,1986
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 441 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M.,
   Springfield, IL, C.C. Thomas, 1970  Volume(issue)/page/year: 2,73,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   14,435,1959
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12 gm/m3/6H
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   10,8,1967
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 mg/m3/2H
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   6,360,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1180 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   6,360,1964
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5010 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0545856
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 16 gm/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,119,1982
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 gm/kg/20W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   19,413,1959

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 556 mg/m3 (100 ppm)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   TOXICOLOGY REVIEW
   BLFSBY Basic Life Sciences.  (Plenum Pub. Corp., 223 Spring St., New York,
   NY 10003)  V.1-    1973-  Volume(issue)/page/year: 24,253,1983

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

   MSHA STANDARD-air:TWA 100 ppm (560 mg/m3)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,274,1971

   OSHA PEL (Gen Indu):8H TWA 100 ppm (560 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 100 ppm (560 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 100 ppm (560 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 100 ppm (560 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-BELGIUM:TWA 100 ppm (556 mg/m3) JAN 1993
   
   OEL-DENMARK:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-FINLAND:TWA 100 ppm (560 mg/m3);STEL 150 ppm;Skin JAN 1993
   
   OEL-FRANCE:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-GERMANY:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-HUNGARY:TWA 300 mg/m3;STEL 600 mg/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-POLAND:TWA 300 mg/m3 JAN 1993
   
   OEL-RUSSIA:STEL 300 mg/m3 JAN 1993
   
   OEL-SWEDEN:TWA 80 ppm (450 mg/m3);STEL 150 ppm (800 mg/m3);Skin JAN 1993
   
   OEL-SWITZERLAND:TWA 100 ppm (560 mg/m3);STEL 200 ppm JAN 1993
   
   OEL-TURKEY:TWA 100 ppm (560 mg/m3) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 100 ppm (560 mg/m3);STEL 150 ppm JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO TURPENTINE-air:10H TWA 100 ppm
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 74990
       No. of Facilities: 12405 (estimated)
       No. of Industries: 139
       No. of Occupations: 92
       No. of Employees: 113949 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5757
       No. of Facilities: 7231 (estimated)
       No. of Industries: 75
       No. of Occupations: 62
       No. of Employees: 116433 (estimated)
       No. of Female Employees: 22205 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 74990
       No. of Facilities: 19493 (estimated)
       No. of Industries: 146
       No. of Occupations: 94
       No. of Employees: 351747 (estimated)
       No. of Female Employees: 144051 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9158
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Turpentine, 1551
   
   NIOSH Analytical Method, 1996: Volatile organic compound, 2549

 
                            *** END OF RECORD ***
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