RTECS NUMBER : ZI2300000
CHEMICAL NAME : Zorbamycin, hydrochloride
CAS REGISTRY NUMBER : 11056-20-5
LAST UPDATED : 199709
DATA ITEMS CITED : 30
MOLECULAR FORMULA : C56-H100-N18-O24-S2.Cu.2Cl-H
MOLECULAR WEIGHT : 1610.32
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Antibiotic 241D dihydrochloride
* 241D dihydrochloride
* NSC 146208
* U-30604E
* Zorbamycin
* Zorbamycin dihydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 22 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo,
MI 49001) Volume(issue)/page/year: 2(6),-,1971
** MUTATION DATA **
TYPE OF TEST : Phage inhibition capacity
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 100 ng/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
43,2819,1983
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-ARAB Republic of Egypt:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
OEL-AUSTRALIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-AUSTRALIA:TWA 1 mg(Cu)/m3 (dust) JAN 1993
OEL-BELGIUM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-BELGIUM:TWA 1 mg(Cu)/m3 (dust) JAN 1993
OEL-DENMARK:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
OEL-DENMARK:TWA 1 mg(Cu)/m3 (dust) JAN 1993
OEL-FINLAND:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-FINLAND:TWA 1 mg(Cu)/m3 (dust) JAN 1993
OEL-FRANCE:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-FRANCE:TWA 1 mg(Cu)/m3;STEL 2 mg(Cu)/m3 (dust) JAN 1993
OEL-GERMANY:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
OEL-GERMAY:TWA 1 mg(Cu)/m3 (dust) JAN 1993
OEL-HUNGARY:TWA 0.2 mg(Cu)/m3;STEL 0.4 mg(Cu)/m3 (dust) JAN 1993
OEL-INDIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-THE NETHERLANDS:TWA 02 mg(Cu)/m3 (fume) JAN 1993
OEL-THE NETHERLANDS:TWA 1 mg(Cu)/m3 (dust) JAN 1993
OEL-THE PHILIPPINES:TWA 1.0 mg(Cu)/m3 (fume) JAN 1993
OEL-POLAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
OEL-RUSSIA:STEL 0.5 ppm (1 mg(Cu)/m3) (dust) JAN 1993
OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (resp. dust) JAN 1993
OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-SWEDEN:TWA 1 mg(Cu)/m3 (total dust) JAN 1993
OEL-SWITZERLAND:TWA 0.1 mg(Cu)/m3;STEL 0.2 mg(Cu)/m3 (fume) JAN 1993
OEL-SWITZERLAND:TWA 1 mg(Cu)/m3;STEL 1 mg(Cu)/m3 JAN 1993
OEL-THAILAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
OEL-THAILAND:TWA 1 mg(Cu)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
*** END OF RECORD ***
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