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MSDS  : Acetic acid, chloro-, 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester
CAS  : 74940-61-7
SYNONYMS  : * Acetic acid, chloro-, ester with dimethyl(2,2,2-trichloro-1-hydroxyethyl)phosphonate * Chloracetofon * Chloracetophon * Chloracetophone * Chloroacetic acid 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester * O,O-Dimethyl (2,2,2-trichloro-1-(chloroacetoxy)ethyl)phosphonate
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AG2750000
CHEMICAL NAME : Acetic acid, chloro-,
2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester
CAS REGISTRY NUMBER : 74940-61-7
OTHER CAS REGISTRY NOS. : 81406-06-6
BEILSTEIN REFERENCE NO. : 1983208
LAST UPDATED : 199806
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C6-H9-Cl4-O5-P
MOLECULAR WEIGHT : 333.92
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Acetic acid, chloro-, ester with
dimethyl(2,2,2-trichloro-1-hydroxyethyl)phosphonate
* Chloracetofon
* Chloracetophon
* Chloracetophone
* Chloroacetic acid 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester
* O,O-Dimethyl (2,2,2-trichloro-1-(chloroacetoxy)ethyl)phosphonate

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 344 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965-
Volume(issue)/page/year: 22,2540,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 421 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 200 mg/kg
SEX/DURATION : female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6,
Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 23,201,1984

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 168 mg/kg
SEX/DURATION : female 1-21 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - delayed effects
REFERENCE :
KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd.
Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year:
26,297,1983

** MUTATION DATA **

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 2 mg/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990

TYPE OF TEST : Micronucleus test
ROUTE OF EXPOSURE : Unreported
TEST SYSTEM : Rodent - hamster
DOSE/DURATION : 60 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990

TYPE OF TEST : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE : Unreported
TEST SYSTEM : Rodent - hamster
DOSE/DURATION : 42 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990

*** END OF RECORD ***
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NAMECAS
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Acetic acid, ((4-chloro-o-tolyl)oxy)-, ethyl ester 2698-38-6
Acetic acid, ((4-chloro-o-tolyl)oxy)-, compd. with2,2'-iminodiethanol (1:1) 20405-19-0
Acetic acid, ((4-chloro-o-tolyl)oxy)-, isooctyl ester 26544-20-7
Acetic acid, ((4-chloro-o-tolyl)oxy)-, methyl ester(8CI) 2436-73-9
Acetic acid, ((4-chloro-o-tolyl)oxy)-, potassium salt 5221-16-9
Acetic acid, ((4-chloro-o-tolyl)oxy)-, sodium salt 3653-48-3
Acetic acid, ((4-chloro-o-tolyl)oxy)thio-, S-ethylester 25319-90-8
Acetic acid, ((4-chloro-o-tolyl)sulfonyl)-, compd.with 2,2',2''-nitrilotrisethanol (1:1) 102582-95-6
Acetic acid, chloro-,2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester 74940-61-7
Acetic acid, (o-(benzylthio)phenyl)-,2-(dimethylamino)ethyl ester, hydrochloride 14200-07-8
Acetic acid, chloro-, 2,4,5-trichlorophenyl ester 5902-69-2
Acetic acid,(4-chloro-2-(alpha,alpha,alpha-trifluoro-m-toluamido)phenyl)- 17194-48-8
Acetic acid,(4-chloro-2-((alpha,alpha,alpha-trifluoro-m-tolyl)carbamoyl)phenoxy)- 35422-42-5
Acetic acid,((4-chloro-6-(2,3-xylidino)-2-pyrimidinyl)thio)- 50892-23-4
Acetic acid, chromium(3+) salt 1066-30-4
Acetic acid, chromium(2+) salt, hydrate 628-52-4
Acetic acid, chromium(3+) salt, hydrate 25013-82-5
Acetic acid, cobalt(2+) salt 71-48-7
Acetic acid, cobalt(3+) salt 917-69-1
Acetic acid, cobalt(2+) salt, tetrahydrate 6147-53-1
Acetic acid, beryllium salt 543-81-7
Acetic acid, copper(2+) salt 142-71-2
Acetic acid, copper(2+) salt, monohydrate 6046-93-1
Acetic acid, cyano- 372-09-8
Acetic acid, cyano-, allyl ester 13361-32-5
Acetic acid, cyano-, benzylidenehydrazide 4974-44-1
Acetic acid, cyano-, butyl ester 5459-58-5
Acetic acid,cyano(1-(cyanomethyl)-2-pyrrolidinylidene)-, ethylester 106345-05-5
Acetic acid,cyano(1-(2-(((dimethylamino)methylene)amino)-2-oxoethyl)-2-pyrrolidinylide ne)-, ethyl ester 126647-18-5
Acetic acid,cyano(1-(2-(((dimethylamino)methylene)amino)-2-thioxoethyl)-2- pyrrolidinylidene)-, ethyl ester 111038-14-3
Acetic acid,alpha-cyano-alpha-(3,5-dimethyl-4-oxacyclohexylidene)-, ethyl ester 10292-81-6
Acetic acid, (4,4'-biphenylylenedithio)di-, compd.with 2,2',2''-nitrilotris(ethanol) (1:2) 87298-97-3
Acetic acid, (2-cyanoethoxy)diphenyl-,2-(dimethylamino)ethyl ester 94916-96-8
Acetic acid, cyano(ethoxyethylidene)-, ethyl ester 64046-50-0
Acetic acid, cyano-, ethyl ester 105-56-6
Acetic acid, cyano-, hexyl ester 13361-53-0
Acetic acid, cyano-, hydrazide 140-87-4
Acetic acid, cyano-, (o-hydroxybenzylidene)hydrazide 140-87-4
Acetic acid, cyano-,(4-hydroxy-3-methoxybenzylidene)hydrazide 140-87-4
Acetic acid, cyano-, isobutyl ester 13361-31-4
Acetic acid, cyano-, isopropyl ester 13361-30-3
Acetic acid, cyano-, 2-methoxyethyl ester 10258-54-5
Acetic acid, 2-(4-biphenylyl)-2-methyl-,2-piperidinoethyl ester 64046-66-8
Acetic acid,((2-cyano-3-(methylamino)phenyl)amino)oxo-,monosodium salt 63365-44-6
Acetic acid, cyano-, methyl ester 105-34-0
Acetic acid, cyano((3-methylphenyl)hydrazono)-, ethylester 3994-20-5
Acetic acid, cyano((4-methylphenyl)hydrazono)-, ethylester 6797-29-1
Acetic acid, cyano((3-methylphenyl)hydrazono)-,methyl ester 59061-89-1

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