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MSDS  : Choline, succinate (21) (ester)
CAS  : 306-40-1
SYNONYMS  : * Choline, succinate (ester) * Choline, succinyl- * Dicholine succinate * Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(N,N,N-trimethyl- * Succinic acid, diester with choline * Succinocholine * Succinoylcholine * Succinylbischoline * Succinyl choline * Succinyldicholine * Suxamethonium * Suxemethonium
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : GA7000000
CHEMICAL NAME : Choline, succinate (2:1) (ester)
CAS REGISTRY NUMBER : 306-40-1
BEILSTEIN REFERENCE NO. : 1805311
REFERENCE : 4-04-00-01451 (Beilstein Handbook Reference)
LAST UPDATED : 199706
DATA ITEMS CITED : 10
MOLECULAR FORMULA : C14-H30-N2-O4
MOLECULAR WEIGHT : 290.46
WISWESSER LINE NOTATION : 1K1&1&2OV2VO2K1&1&1 &Q &Q
COMPOUND DESCRIPTOR : Drug
Human
SYNONYMS/TRADE NAMES :
* Choline, succinate (ester)
* Choline, succinyl-
* Dicholine succinate
* Ethanaminium,
2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(N,N,N-trimethyl-
* Succinic acid, diester with choline
* Succinocholine
* Succinoylcholine
* Succinylbischoline
* Succinyl choline
* Succinyldicholine
* Suxamethonium
* Suxemethonium

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Human
DOSE/DURATION : 1430 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea
or bronchi
REFERENCE :
ANATAE Anaesthesist. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin
33, Fed. Rep. Ger.) V.1- 1952- Volume(issue)/page/year: 21,27,1972

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Human - infant
DOSE/DURATION : 1600 ug/kg
TOXIC EFFECTS :
Cardiac - other changes
REFERENCE :
BJANAD British Journal of Anesthesia. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1923- Volume(issue)/page/year:
58,576,1986

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 1818 ug/kg
TOXIC EFFECTS :
Cardiac - other changes
REFERENCE :
SAMJAF South African Medical Journal. (Medical Assoc. of South Africa,
Secy., P.O. Box 643, Cape Town, S. Africa) V.6- 1932-
Volume(issue)/page/year: 68,601,1985

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New
York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year:
21,473,1958

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes,
C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973
Volume(issue)/page/year: -,-,1965

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2140 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 152,277,1964

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 7500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 15,126,1965

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 280 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD
Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970-
Volume(issue)/page/year: 1,141,1970

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 88,1,1951

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 88,1,1951

*** END OF RECORD ***
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NAMECAS
Choline, iodide, propionate 2494-55-5
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Choline, iodide, propylidenedicarbamate (21) 63939-06-0
5-beta-Card-20(22)-enolide,3-beta,14-dihydroxy-12-oxo- 2842-85-5
Choline, iodide, sebacoylbis(methylcarbamate) (21) 2842-85-5
Choline, iodide, succinate (21) 541-19-5
Choline, iodide, succinylbis(methylcarbamate) (21) 541-19-5
Choline, iodide, terephthalate (21) 16051-54-0
Choline, iodide, tetramethylenedicarbamate (21) 16051-54-0
Choline, iodide, trimethylenedicarbamate (21) 16051-54-0
Choline, compd. with3-isobutyl-1-methyl-6-thioxanthine (1:1) 16051-54-0
Choline, compd. with3-isopentyl-1-methyl-6-thioxanthine (1:1) 16051-54-0
Choline, methanesulfonate (ester) 3922-85-8
Choline, beta-methyl-, butylether, hydrochloride 63939-07-1
5-alpha-Card-20(22)-enolide,3-beta,14-dihydroxy-19-oxo- 468-20-2
Choline, methyl ether, hydrochloride 25728-47-6
Choline, compd. with1-methyl-3-(2-methylallyl)-6-thioxanthine (1:1) 25728-47-6
Choline, beta-methyl-, methylether, hydrochloride 63938-96-5
Choline, compd. with 1-methyl-3-pentyl-6-thioxanthine(1:1) 63938-96-5
Choline, compd. with1-methyl-3-phenethyl-6-thioxanthine (1:1) 63938-96-5
Choline, inner salt, methylphosphonofluoridate 63938-96-5
Choline, compd. with 1-methyl-3-propyl-6-thioxanthine(1:1) 63938-96-5
Choline, monoester with potassium xanthate 63938-96-5
Choline, inner salt,(2-(1-naphthylmethyl)-2-pyrrolin-1-yl)phosphonate 100857-68-9
Choline nitrate (ester), bromide 63938-97-6
Card-20(22)-enolide, 3,14-dihydroxy-19-oxo-,(3-beta,5-beta,16-beta)- 468-17-7
Choline, nitrate (ester), hydroxide 543-17-9
Choline nitrate (ester), nitrate 26511-30-8
Choline, nitrate, perchlorate 26511-30-8
Choline, compd. with 8-nitrotheophylline (11) 26511-30-8
Choline, picrate, imidazole-4-acetate, picrate 26511-30-8
Choline, picrate, imidazole-4-butyrate, picrate 26511-30-8
Choline, picrate, imidazole-4-propionate, picrate 26511-30-8
Choline, picrate, 3-pyridazineacrylate 110061-37-5
Choline, picrate, 3-pyridazinepropionate 110061-37-5
Choline, picrate, 2-pyridineacrylate 110061-37-5
5-beta-Card-20(22)-enolide,12-beta,14-dihydroxy-3-oxo- 4442-17-5
Choline, picrate, 4-pyrimidinepropionate, picrate 4442-17-5
Choline, salicylate 2016-36-6
Choline, salt with 2-propylvaleric acid (11) 13943-50-5
Choline, succinate (21) (ester) 306-40-1
Choline, compd. with theobromine 306-40-1
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Choline, compd. with 6-thiotheobromine (11) 4499-40-5
Choline, compd. with 6-thiotheophylline (11) 4499-40-5
Choline, compd. with 1,3,8-trimethyl-6-thioxanthine(1:1) 4499-40-5
Chondodendron limaciifolium (diels) Mold., extract 4499-40-5
5-beta-Card-20(22)-enolide,3-beta,14-dihydroxy-12-oxo-, 3-acetate 2842-86-6
Chondrocurarine, 7'-O-methyl-, diiodide, trihydrate 2842-86-6

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