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MSDS  : Cobinamide, O-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
CAS  : 13870-90-1
SYNONYMS  : * Adenosylcobalamin * Calomide * Cobalamine coenzyme * Cobamamide * Coenzyme B12 * DBC coenzyme * Deoxyadenosylcobalamin * 5-Deoxyadenosylcobalamin * 5'-Deoxyadenosylcobalamin * 5'-Deoxyadenosyl vitamin B12 * Dibencozide * Funacomide * LM 176 * Vitamin B12 coenzyme
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : GG3800000
CHEMICAL NAME : Cobinamide, O-(5'-deoxyadenosine-5') deriv.,
hydroxide, dihydrogen phosphate (ester), inner salt,
3'-ester with
5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
CAS REGISTRY NUMBER : 13870-90-1
BEILSTEIN REFERENCE NO. : 4122932
LAST UPDATED : 199612
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C72-H100-Co-N18-O17-P
MOLECULAR WEIGHT : 1579.80
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Adenosylcobalamin
* Calomide
* Cobalamine coenzyme
* Cobamamide
* Coenzyme B12
* DBC coenzyme
* Deoxyadenosylcobalamin
* 5-Deoxyadenosylcobalamin
* 5'-Deoxyadenosylcobalamin
* 5'-Deoxyadenosyl vitamin B12
* Dibencozide
* Funacomide
* LM 176
* Vitamin B12 coenzyme

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,405,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,405,1990

*** END OF RECORD ***
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NAMECAS
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Cobalt,(ethanedioato(2-)-O,O')bis(3-((phenylamino)methyl)-2(3H)-benzoxazolone- N(sup N(sup 3),O(sup 2))- 82497-97-0
Cobalt, (ethanedioato(2-)-O,O')bis(pyridine1-oxide-O)-, (T-4)- 74167-21-8
Cobalt(II),N,N'-ethylenebis(3-fluorosalicylideneiminato)- 62207-76-5
Cobalt, N,N'-ethylenebis(salicylideneiminato)- 14167-18-1
Cobalt(II)fluoborate 26490-63-1
Cobalt(II) fluoride 10026-17-2
Cobalt(3+), hexaammine-, (OC-6-11)-, triacetate 14023-85-9
Cobalt hydrocarbonyl 16842-03-8
Cobalt hydroxide 1307-86-4
Cobalt(II) hydroxide 21041-93-0
Citric acid, triethyl ester 77-93-0
Civet absolute 68916-26-7
Cobalt hydroxide oxide 12016-80-7
Cobalt, complex with niacinamide 12016-80-7
Cobalt(II) nitrate (12) 10141-05-6
Cobalt oxide (Co3O4) 1308-06-1
Cobalt(2+) oxide 1307-96-6
Cobalt(III) oxide 1308-04-9
Cobalt(II) perchlorate, hexahydrate 13478-33-6
Cobalt(II) sulfate (11) 10124-43-3
Cobalt(II) sulfate (11), heptahydrate 10026-24-1
Cobalt sulfide 12013-10-4
Cladomycin 100927-16-0
Cobalt(2+) sulfide 1317-42-6
Cobalt, triammine(2-oxopentanedioato(2-)-O(sup1),O(sup 2),O(sup 5))- 132829-10-8
Cobalt, tri-mu-carbonylnonacarbonyltetra-,tetrahydro- 17786-31-1
Cobalt(3+), tris(2,2'-bipyridine-N,N')-, perchlorate(1:3), (OC-6-11)- 14376-02-4
Cobalt(2+), tris(1,2-ethanediamine-N,N')-,(OC-6-11)-, (T-4)-tetraoxotungstate(2-) (1:1),pentahydrate 80669-48-3
Cobalt, tris(octamethylpyrophosphoramide)-,diperchlorate(1-) 80669-48-3
Cobalt(2+), tris(octamethylpyrophosphoramide)-,diperchlorate 26167-79-3
Cobalt(2+), tris(1,2-propanediamine-N,N')-,(T-4)-tetraoxotungstate(2-) (1:1), pentahydrate 80660-43-1
Cobinamide, acetate (salt) hydroxide, dihydrogenphosphate (ester), inner salt, 3'-ester with5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole 22465-48-1
Cobinamide, cobalt-methyl derivative, hydroxide,dihydrogen phosphate (ester), inner salt, 3'-esterwith5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole 13422-55-4
Clarified slurry oil 64741-62-4
Cobinamide, cyanide phosphate 3'-ester with5,6-dimethyl-1-alpha-D- ribofuranosylbenzimidazole,inner salt 68-19-9
Cobinamide, O-(5'-deoxyadenosine-5') deriv.,hydroxide, dihydrogen phosphate (ester), inner salt,3'-ester with5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole 13870-90-1
Cobinamide, dihydroxide, dihydrogen phosphate(ester), mono (inner salt), 3'- ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole 13422-51-0
Cobramin ASUBSTANCE DEFINITION :Isolated from the venom of Naja najaREFERENCE :BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,Fairview Park, Elmsford, NY 10523) V.1- 1958- 13422-51-0
Cobramin B 12777-56-9
Cobrotoxin 12584-83-7
Coca leaf, extract 12584-83-7
Coccinia grandis (L.)Voigt, extractSUBSTANCE DEFINITION :Plant belonging to the family CucurbitaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 12584-83-7
Coccinia indica W. & A., root extractSUBSTANCE DEFINITION :Plant belonging to the family CucurbitaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 12584-83-7
Cocculus hirsutus (linn.) Diels, extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family MenispermaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977 12584-83-7
Clary sage oil 8016-63-5
Cocculus laurifolius DC., extractSUBSTANCE DEFINITION :Plant belonging to the family MenispermaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 8016-63-5
Cocculus pendulus (forst) Diels, extractSUBSTANCE DEFINITION :Plant belonging to the family MenispermaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- 8016-63-5

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