*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LQ6475000
CHEMICAL NAME : Formic acid, chloro-, isopropyl ester
CAS REGISTRY NUMBER : 108-23-6
BEILSTEIN REFERENCE NO. : 0506416
REFERENCE : 4-03-00-00024 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C4-H7-Cl-O2
MOLECULAR WEIGHT : 122.56
WISWESSER LINE NOTATION : GVOY1&1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* Carbonochloride acid, 1-methylethyl ester
* Chloroformic acid isopropyl ester
* Isopropyl chlorocarbonate
* Isopropyl chloromethanoate
* Isopropylester kyseliny chlormravenci
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REFERENCE :
IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological
Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year:
6,1,1967
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Severe
REFERENCE :
IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological
Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year:
6,1,1967
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1070 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological
Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year:
6,1,1967
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 200 ppm/5H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
BJIMAG British Journal of Industrial Medicine. (British Medical Journal,
Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year:
27,1,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 178 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson,
M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978
Volume(issue)/page/year: 4,758,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson,
M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978
Volume(issue)/page/year: 4,758,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 11300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological
Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year:
6,1,1967
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 50 ppm/6H/2W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Blood - hemorrhage
Related to Chronic Data - death
REFERENCE :
BJIMAG British Journal of Industrial Medicine. (British Medical Journal,
Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year:
27,1,1970
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-RUSSIA:STEL 0.1 mg/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 1 ppm (5 mg/m3) JAN 1993
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
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Formhydroxamic acid
| 4312-87-2 |
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Formic acid
| 64-18-6 |
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Formic acid,1-benzyl-2-(4,6-dimethyl-3-pyridazinyl)hydrazide
| 17258-16-1 |
|
Formic acid, benzyl ester
| 104-57-4 |
|
Formic acid, 2,2-bis(2-chloroethyl)hydrazide
| 98069-43-3 |
|
Formic acid, butyl ester
| 592-84-7 |
|
Formic acid, 1-butylhydrazide
| 16120-70-0 |
|
Formic acid, cadmium salt
| 4464-23-7 |
|
Formic acid, calcium salt
| 544-17-2 |
|
Fobos M-2
| 78922-31-3 |
|
Formaldehyde, (5-nitro-2-pyridyl)hydrazone
| 28050-83-1 |
|
Formic acid, chloro-, allyl ester
| 2937-50-0 |
|
Formic acid, chloro-, 2-chloroethyl ester
| 627-11-2 |
|
Formic acid, chloro-, ethylene ester
| 124-05-0 |
|
Formic acid, chloro-, ethyl ester
| 541-41-3 |
|
Formic acid,4-(3-(2-chloroethyl)-3-nitrosoureido)cyclohexylester, (E)-
| 67227-29-6 |
|
Formic acid, chloro-, fluoren-9-ylmethyl ester
| 28920-43-6 |
|
Formic acid, chloro-, 2-fluoroethyl ester
| 462-27-1 |
|
Formic acid, chloro-, isopropyl ester
| 108-23-6 |
|
Formic acid, chloro-, 1-naphthyl ester
| 3759-61-3 |
|
Formic acid, chloro-, oxydiethylene ester
| 106-75-2 |
|
Formaldehyde, nitro-, p-tolylhydrazone
| 37703-97-2 |
|
Formic acid, chloro-, propyl ester
| 109-61-5 |
|
Formic acid, chlorothio-, S-methyl ester
| 18369-83-0 |
|
Formic acid, chlorothio-, S-propyl ester
| 13889-92-4 |
|
Formic acid, chloro-, trichloromethyl ester
| 503-38-8 |
|
Formic acid, chloro-, 2,4,6-trichlorophenyl ester
| 4511-19-7 |
|
Formic acid, cyano-, methyl ester
| 17640-15-2 |
|
Formic acid, compd. with cyclohexanamine (11)
| 34961-28-9 |
|
Formic acid,(((6,8-dibromo-3-(2-chlorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl) sulfonyl)-, methyl ester
| 108659-80-9 |
|
Formic acid,(((6,8-dibromo-3,4-dihydro-3-(2-methoxyphenyl)-4-oxo-2-quinazolinyl)methyl) sulfonyl)-, methyl ester
| 108659-75-2 |
|
Formic acid, compd. with1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9- one N-oxide (1:1)
| 64265-19-6 |
|
Formaldehyde, oxime
| 75-17-2 |
|
Formic acid, dithiobis(thio-, O,O-diethyl ester
| 502-55-6 |
|
Formic acid, dithiobis(thio-, O,O-dimethyl ester
| 1468-37-7 |
|
Formic acid, ethyl ester
| 109-94-4 |
|
Formic acid, 1-ethylhydrazide
| 74920-78-8 |
|
Formic acid, ethylidenemethylhydrazide
| 16568-02-8 |
|
Formic acid, 2-(4-(2-furyl)-2-thiazolyl)hydrazide
| 31873-81-1 |
|
Formic acid, heptyl ester
| 112-23-2 |
|
Formic acid, hexyl ester
| 629-33-4 |
|
Formic acid, hexylidenemethylhydrazide
| 57590-22-4 |
|
Formic acid, hydrazide
| 624-84-0 |
|
Formaldehyde, polymer with benzenamine
| 25214-70-4 |
|
Formic acid, hydrazodi-
| 628-36-4 |
|
Formic acid, indium(3+) salt
| 40521-21-9 |
|
Formic acid, isobutyl ester
| 542-55-2 |
|
Formic acid, isopropyl ester
| 625-55-8 |
|
Formic acid, methyl ester
| 107-31-3 |
|
Formic acid, methylhydrazide
| 758-17-8 |
|
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