*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LT1830000
CHEMICAL NAME : Fumaric acid, disodium salt
CAS REGISTRY NUMBER : 17013-01-3
LAST UPDATED : 199107
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C4-H2-O4.2Na
MOLECULAR WEIGHT : 160.04
WISWESSER LINE NOTATION : QV1U1VQ &-NA- 2 -T
COMPOUND DESCRIPTOR : Drug
Human
SYNONYMS/TRADE NAMES :
* Disodium fumarate
* Fumaran sodny
* Sodium fumarate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human
DOSE/DURATION : 215 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
Gastrointestinal - other changes
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 31,1,1942
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 8 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,314,1986
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2420 mg/kg
TOXIC EFFECTS :
Behavioral - irritability
Blood - hemorrhage
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 35,298,1946
TYPE OF TEST : LD10 - Lethal Dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3680 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 31,12,1942
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 31,1,1942
*** END OF RECORD ***
|
|
|
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Fuel oil No. 6
| 68553-00-4 |
Fuel oil, pyrolyzate
| 68553-00-4 |
Fuel oil, residual
| 68476-33-5 |
Fuel oils
| 68476-33-5 |
Formamide, N-(1-adamantyl-1-ethyl)-
| 101468-16-0 |
Fuels, diesel, No. 2
| 68476-34-6 |
Fulminic acid, silver(1+) salt
| 5610-59-3 |
Fulvic acid, sodium salt
| 5610-59-3 |
Fulvomycin A
| 57608-60-3 |
Fulvomycin A, sodium salt
| 101975-66-0 |
Fulvomycin B
| 57608-61-4 |
Fulvomycin B, sodium salt
| 101975-67-1 |
Fulvomycin C
| 57608-62-5 |
Fulvomycin C, sodium salt
| 101975-68-2 |
Fulvotomentosaside
| 101975-68-2 |
Formamide, N-(1-adamantyl-1-hexyl)-
| 101468-17-1 |
Fumaramic acid, N-(5-methyl-1,3,4-thiadiazol-2-yl)-
| 101468-17-1 |
Fumaramic acid, N-(4-phenyl-2-thiazolyl)-
| 101468-17-1 |
Fumaramic acid, N-(5-propyl-1,3,4-thiadiazol-2-yl)-,methyl ester
| 101468-17-1 |
Fumaria officinalis, alkaloidal extract
| 101468-17-1 |
Fumaria officinalis Linn., seed extractSUBSTANCE DEFINITION :Plant belonging to the family FumariaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 101468-17-1 |
Fumaria parviflora Lamk., extractSUBSTANCE DEFINITION :Plant belonging to the family FumariaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 101468-17-1 |
Fumaria vaillantii Loisel, alkaloidal fractionSUBSTANCE DEFINITION :Plant belonging to the family FumariaceaeREFERENCE :QJDRAZ Quarterly Journal of Crude Drug Research. (Lisse, Netherlands)V.1-19, 1961-81. For publisher information, see IJCREE.
| 101468-17-1 |
Fumaric acid
| 110-17-8 |
Fumaric acid, chlorinated
| 110-17-8 |
Fumaric acid, compd. with 3-(2-aminoethyl)indol-5-ol,acetate (1:2:2)
| 110-17-8 |
Formamide, N-(2-adamantyl)-, hydrochloride
| 74525-97-6 |
Fumaric acid, (6-benzamido-m-anisidino)-, dimethylester
| 19271-17-1 |
Fumaric acid, bis(3-allyloxy-2-hydroxypropyl) ester
| 5975-73-5 |
Fumaric acid, bis(2-aminoethyl) ester,dihydrochloride
| 4126-70-9 |
Fumaric acid, bis(2-(2-chloroethoxy)ethyl) ester
| 63957-09-5 |
Fumaric acid, bis(2-chloroethyl) ester
| 5335-09-1 |
Fumaric acid, bis(2-ethylhexyl) ester
| 141-02-6 |
Fumaric acid, bis(p-methoxyphenyl) ester
| 31263-13-5 |
Fumaric acid, bis(2-naphthyl) ester
| 73839-82-4 |
Fumaric acid, alpha-butylbenzyl ester
| 97405-37-3 |
Fumaric acid, butyl 2,3-epoxypropyl ester
| 25876-07-7 |
Formamide, N-(1-adamantyl-1-propyl)-
| 101468-18-2 |
Fumaric acid, dibutyl ester
| 105-75-9 |
Fumaric acid, dihexyl ester
| 19139-31-2 |
Fumaric acid, dihydrazide
| 3538-81-6 |
Fumaric acid, dihydroxy-
| 133-38-0 |
Fumaric acid, dihydroxy-, mixed with1-deoxy-1-(methylamino)-D-glucitol
| 133-38-0 |
Fumaric acid, dihydroxy-, dimethyl ester
| 133-47-1 |
Fumaric acid, dihydroxy-, dimethyl ester, diacetate
| 130-84-7 |
Fumaric acid, diisobutyl ester
| 7283-69-4 |
Fumaric acid, diisopropyl ester
| 7283-70-7 |
Fumaric acid, disodium salt
| 17013-01-3 |
Formamide,N-(5-amino-2-((5-(1,3-dioxoisoindolin-2-yl)pentyl)oxy)benzyl)-
| 5819-82-9 |
Fumaric acid, 1,4-dithio-, S,S-diphenyl ester
| 73839-62-0 |
|
|