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MSDS  : Acridine, 9-amino-, hydrochloride
CAS  : 134-50-9
SYNONYMS  : * Acramine Yellow * 9-Acridinamine, monohydrochloride * Aminacrine hydrochloride * 5-Aminoacridine hydrochloride * 9-Aminoacridine hydrochloride * 9-Aminoacridine monohydrochloride * Monacrin hydrochloride * NSC-7571
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AR7350000
CHEMICAL NAME : Acridine, 9-amino-, hydrochloride
CAS REGISTRY NUMBER : 134-50-9
LAST UPDATED : 199701
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C13-H10-N2.Cl-H
MOLECULAR WEIGHT : 230.71
WISWESSER LINE NOTATION : T C666 BNJ IZ &GH
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Acramine Yellow
* 9-Acridinamine, monohydrochloride
* Aminacrine hydrochloride
* 5-Aminoacridine hydrochloride
* 9-Aminoacridine hydrochloride
* 9-Aminoacridine monohydrochloride
* Monacrin hydrochloride
* NSC-7571

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 78 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,7,1969

** MUTATION DATA **

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 10 ug/plate
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 16,6240,1982

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 50 ug/plate
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 17,70,1983

TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 60 ug/disc
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 97,1,1982

TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 60 ug/disc
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 97,1,1982

TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 600 ug/L
REFERENCE :
GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring
St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year:
27,95,1981

TYPE OF TEST : DNA adduct
TEST SYSTEM : Mammal - species unspecified Lymphocyte
DOSE/DURATION : 10 pph
REFERENCE :
BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY
10158) V.1- 1963- Volume(issue)/page/year: 11,2537,1972

*** REVIEWS ***

TOXICOLOGY REVIEW
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
13,747,1989

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 04770
No. of Facilities: 68 (estimated)
No. of Industries: 1
No. of Occupations: 6
No. of Employees: 2770 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 04770
No. of Facilities: 9 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 166 (estimated)
No. of Female Employees: 105 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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