*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AU7100000
CHEMICAL NAME : Adenine, 9-beta-D-psicofuranosyl-
CAS REGISTRY NUMBER : 1874-54-0
BEILSTEIN REFERENCE NO. : 0095142
REFERENCE : 4-26-00-03694 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C11-H15-N5-O5
MOLECULAR WEIGHT : 297.31
WISWESSER LINE NOTATION : T56 BN DN FN HNJ IZ D- BT5OTJ B1Q CQ DQ E1Q
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 6-Amino-9-D-psicofuranosylpurine
* Angustmycin C
* 1'-(Hydroxymethyl)adenosine
* Psicofuranine
* Psicofuranosyladenine
* 9-D-Psicofuranosyl-6-aminopurine
* 9-beta-D-Psicofuranosyl-9H-purin-6-amine
* 9H-Purin-6-amine, 9-beta-D-psicofuranosyl-
* U-9586
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10 gm/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC)
V.1-12, 1951-62. For publisher information, see CLMEA3.
Volume(issue)/page/year: 9,675,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
eds., Washington, DC, American Soc. for Microbiology, 1978
Volume(issue)/page/year: 1,842,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1695 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo,
MI 49001) Volume(issue)/page/year: 2(6),-,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 6 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
eds., Washington, DC, American Soc. for Microbiology, 1978
Volume(issue)/page/year: 1,842,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo,
MI 49001) Volume(issue)/page/year: 2(6),-,1971
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 9800 mg/kg/28D-I
TOXIC EFFECTS :
Liver - other changes
Blood - other changes
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC)
V.1-12, 1951-62. For publisher information, see CLMEA3.
Volume(issue)/page/year: 9,675,1959
*** REVIEWS ***
TOXICOLOGY REVIEW
CRTXB2 CRC Critical Reviews in Toxicology. (CRC Press, Inc., 2000 Corporate
Blvd., NW, Boca Raton, FL 33431) V.1- 1971- Volume(issue)/page/year:
2,159,1973
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
1-Adamantanol
| 768-95-6 |
2-Adamantanol, 1-(3-methylaminopropyl)-,hydrochloride
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3-Adamantanol, 1-(2-methylaminopropyl)-,hydrochloride
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2-Adamantanol, 1-(4-methyl-1-piperazinyl)methyl-,dihydrochloride
| 59177-68-3 |
2-Adamantanone
| 700-58-3 |
2-Adamantanone, oxime
| 4500-12-3 |
Acridine, 9-amino-2-ethoxy-6-nitro-
| 20304-70-5 |
Adansonia digitata Linn., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family MalvaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 20304-70-5 |
Additive 117
| 65650-98-8 |
Additive basic calcium alkylsalicylicate
| 65650-98-8 |
Additive kasp-13
| 65650-98-8 |
Additive 117/T
| 62449-74-5 |
Adelocaryum coelestinum (lindl.) Brand., extractSUBSTANCE DEFINITION :Plant belonging to the family BoraginaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 62449-74-5 |
Adenanthera paronina Linn., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family LeguminosaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 62449-74-5 |
Adenia cissampeloides (planch ex Benth.), rootextractSUBSTANCE DEFINITION :Plant belonging to the family PassifloraceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:5,187,1982
| 62449-74-5 |
Adenia heterophylla (bl.) Koord ssp. andmanica deWillde, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family PassifloraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 62449-74-5 |
Adenine
| 73-24-5 |
Acridine, 9-amino-, hydrochloride
| 134-50-9 |
Adenine, 9-beta-D-arabinofuranosyl-
| 5536-17-4 |
Adenine, 9-beta-D-arabinofuranosyl-, 5'-(dihydrogenphosphate)
| 29984-33-6 |
Adenine, 9-beta-D-arabinofuranosyl-2-fluoro-
| 21679-14-1 |
Adenine, 9-beta-D-arabinofuranosyl-, monohydrate
| 24356-66-9 |
Adenine, N-benzyl-
| 1214-39-7 |
Adenine, 9-benzyl-
| 4261-14-7 |
Adenine, 9-cyclohexyl-2-propoxy-
| 73535-50-9 |
9H-Adenine, 9-cyclopentyl-
| 715-91-3 |
Adenine,9-(6-deoxy-beta-D-erythro-hex-5-enulofuranosyl)-
| 2004-04-8 |
Adenine, dihydriodide
| 73663-94-2 |
Acridine, 9-amino-2-methoxy-
| 3407-99-6 |
Adenine, 7,8-dihydro-N-benzyl-
| 102366-79-0 |
Adenine, 2-fluoro-
| 700-49-2 |
7H-Adenine, N-(p-fluorophenyl)-
| 73663-95-3 |
Adenine, N-furfuryl-
| 525-79-1 |
Adenine, hydriodide
| 73663-96-4 |
Adenine, N-hydroxy-
| 5667-20-9 |
Adenine, N-hydroxy-, 3-oxide
| 21959-46-6 |
Adenine, N-hydroxy-9-ribofuranosyl-
| 3414-62-8 |
7H-Adenine, N-(o-methoxyphenyl)-
| 73663-97-5 |
Adenine, 2-methyl-
| 1445-08-5 |
Acridine, 9-amino-1-methyl-
| 23045-11-6 |
Adenine, 3-methyl-
| 5142-23-4 |
Adenine, 3-(3-methyl-2-butenyl)-, hydrochloride
| 63905-28-2 |
Adenine, N-methyl-N-nitroso-
| 21928-82-5 |
Adenine 1-oxide
| 700-02-7 |
Adenine, phosphate
| 52175-10-7 |
Adenine, 9-beta-D-psicofuranosyl-
| 1874-54-0 |
Adenine, 9-beta-D-psicofuranosyl-,1',3',4',6'-tetraacetate
| 1874-54-0 |
Adenine, sulfate (21)
| 321-30-2 |
Adenosine
| 58-61-7 |
Adenosine, N-(2-(5-acetyl-1H-indol-3-yl)ethyl)-
| 58-61-7 |
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