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MSDS  : Hydroxylamine, N-phenyl-
CAS  : 100-65-2
SYNONYMS  : * Aniline, N-hydroxy- * Benzenamine, N-hydroxy- * N-Hydroxyaniline * N-Hydroxybenzenamine * NCI-C60093 * Phenylhydroxyamine * Phenylhydroxylamine * beta-Phenylhydroxylamine * N-Phenylhydroxylamine
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : NC4900000
CHEMICAL NAME : Hydroxylamine, N-phenyl-
CAS REGISTRY NUMBER : 100-65-2
BEILSTEIN REFERENCE NO. : 0507174
REFERENCE : 4-15-00-00004 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C6-H7-N-O
MOLECULAR WEIGHT : 109.14
WISWESSER LINE NOTATION : QMR
COMPOUND DESCRIPTOR : Mutagen
Human
SYNONYMS/TRADE NAMES :
* Aniline, N-hydroxy-
* Benzenamine, N-hydroxy-
* N-Hydroxyaniline
* N-Hydroxybenzenamine
* NCI-C60093
* Phenylhydroxyamine
* Phenylhydroxylamine
* beta-Phenylhydroxylamine
* N-Phenylhydroxylamine

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 500 ug/kg
TOXIC EFFECTS :
Skin and Appendages - primary irritation (after topical exposure)
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig,
Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC.
Volume(issue)/page/year: 35,401,1895

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - hematuria
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 182,118,1936

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 247 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig,
Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC.
Volume(issue)/page/year: 35,401,1895

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1060 mg/kg/13W-C
TOXIC EFFECTS :
Behavioral - food intake (animal)
Blood - changes in spleen
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 10,671,1972

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 34 gm/kg/50D-I
TOXIC EFFECTS :
Blood - other changes
Nutritional and Gross Metabolic - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979

** MUTATION DATA **

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 100 ug/plate
REFERENCE :
NTPTB* NTP Technical Bulletin. (National Toxicology Program, Landow Bldg.
3A-06, 7910 Woodmont Ave., Bethesda, MD 20205) Volume(issue)/page/year:
JAN1982

TYPE OF TEST : Gene conversion and mitotic recombination
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 2 umol/L
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
Volume(issue)/page/year: 86,155,1995

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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NAMECAS
Hydroxylamine, O-phenethyl-, maleate 96651-33-1
Hydroxylamine, O-(2-phenoxyethyl)- 73941-29-4
Hydroxylamine, N-phenyl- 100-65-2
Hydroxylamine, N-(p-(phenylazo)phenyl)- 6530-27-4
Hydroxylamine, N-phenylazophenyl-, hydrochloride 6530-27-4
Hydroxylamine, O,O'-(m-phenylenedimethylene)di-,dihydrochloride 30777-80-1
Hydroxylamine, O,O'-(o-phenylenedimethylene)di-,dihydrochloride 30777-79-8
Hydrazine,1-(2-methoxyisonicotinoyl)-2-(2-methylisonicotinoyl)- 30777-79-8
Hydroxylamine, O,O'-(p-phenylenedimethylene)di-,dihydrochloride 30777-81-2
Hydroxylamine, O-(3-phenylpropyl)-, hydrochloride 73941-30-7
Hydroxylamine, N-(p-(phenylthio)phenyl)- 21229-99-2
Hydroxylamine, N-(p-styrylphenyl)-, (E) 60462-51-3
Hydroxylamine, sulfate (21) 10039-54-0
Hydroxylamine-O-sulfonic acid 2950-43-8
Hydroxylamine-O-sulfonic acid,N-acetyl-N-(4-biphenylyl)- 2950-43-8
Hydroxylamine-O-sulfonic acid,N-acetyl-N-(2-phenanthrenyl)-, potassium salt 41935-81-3
Hydroxylamine-O-sulfonic acid,N-(4-butoxyphenylacetyl)-, pyridine salt 77372-66-8
Hydroxylamine-O-sulfonic acid,N-(9-chloro-4,5-dihydro-2-(2-naphthalenyl)-6H-imidazo(4,5,1-ij)quinolin-6-ylidene)-, potassium salt 134601-10-8
Hydrazine, (p-methoxy-alpha-methylbenzyl)-, oxalate 75333-11-8
Hydroxylamine-O-sulfonic acid,N-(9-chloro-4,5-dihydro-2-phenyl-6H-imidazo(4,5,1-ij)quinolin-6-ylidene)-, potassium salt 134601-13-1
Hydroxylamine-O-sulfonic acid,N-(9-chloro-4,5-dihydro-2-(phenylmethyl)-6H-imidazo(4,5,1-ij) quinolin-6-ylidene)-, potassium salt 134601-06-2
Hydroxylamine-O-sulfonic acid,N-(9-chloro-2-(1-ethylpropyl)-4,5-dihydro-6H-imidazo(4,5,1-ij) quinolin-6-ylidene)-, potassium salt 134601-07-3
Hydroxylamine-O-sulfonic acid,N-(9-chloro-2-(3-furanyl)-4,5-dihydro-6H-imidazo(4,5,1-ij) quinolin-6-ylidene)-, potassium salt 134601-11-9
Hydroxylamine-O-sulfonic acid, N-(2-naphthoyl)-,pyridine salt 77372-69-1
Hydroxylamine, N-(1,2,3,4-tetrahydro-2-naphthyl)-,hydrochloride,(+-)- 90874-76-3
Hydroxylamine, N-thenyl-, hydrochloride 73941-31-8
Hydroxylamine, N-(m-tolyl)- 620-25-7
Hydroxylamine, N-o-tolyl- 611-22-3
Hydroxylamine, N-(p-tolyl)- 623-10-9
Hydrazine, 1-(p-methoxy-alpha-methyl)phenethyl- 1743-42-6
Hydroxylamine, N-(4-(o-tolylazo)-o-tolyl)- 84249-59-2
Hydroxylamine, O-(m-(trifluoromethyl)benzyl)-,hydrochloride 15256-07-2
Hydroxylamine, O-(3,4,5-trimethoxybenzyl)-,hydrochloride 2173-27-5
Hydroxylamine, O-(2-(3,4,5-trimethoxyphenyl)ethyl)-,hydrochloride 2173-27-5
Hydroxylamine, N-(2,3-xylyl)- 3096-62-6
Hydroxylamine, N-(2,5-xylyl)- 3096-64-8
Hydroxylamine, N-(2,6-xylyl)- 3096-63-7
Hydroxylamine, N-(3,4-xylyl)- 43192-07-0
Hydroxypropyl cellulose 9004-64-2
N-Hydroxypropyldiethylenetriamine 1331-27-7
Hydrazine, 1-(o-methoxy-alpha-methylphenethyl)-,hydrochloride 102571-01-7
Hydroxypropyl methylcellulose 9004-65-3
Hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)car bonyl)- 2-methoxy-24-methyl- 88899-56-3
Hygrolytin 53988-66-2
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Hygroscopin A 1403-77-6
Hygroscopin B 1403-78-7
Hygrostatin 71767-91-4
Hymenaea courbaril L., leaf and stem extractSUBSTANCE DEFINITION :Plant belonging to the family CaesalpiniaceaeREFERENCE :JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of GreatBritain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-Volume(issue)/page/year: 16,115,1964 71767-91-4
Hymenoxys odorata, ground plant less rootsSUBSTANCE DEFINITION :Plant belonging to the family Compositae (sunflower)REFERENCE :SOVEA7 Southwestern Veterinarian. (College of Veterinary Medicine, Texas A& M Univ., College Station, TX 77843) V.1- 1948- 71767-91-4

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