*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NC4900000
CHEMICAL NAME : Hydroxylamine, N-phenyl-
CAS REGISTRY NUMBER : 100-65-2
BEILSTEIN REFERENCE NO. : 0507174
REFERENCE : 4-15-00-00004 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C6-H7-N-O
MOLECULAR WEIGHT : 109.14
WISWESSER LINE NOTATION : QMR
COMPOUND DESCRIPTOR : Mutagen
Human
SYNONYMS/TRADE NAMES :
* Aniline, N-hydroxy-
* Benzenamine, N-hydroxy-
* N-Hydroxyaniline
* N-Hydroxybenzenamine
* NCI-C60093
* Phenylhydroxyamine
* Phenylhydroxylamine
* beta-Phenylhydroxylamine
* N-Phenylhydroxylamine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 500 ug/kg
TOXIC EFFECTS :
Skin and Appendages - primary irritation (after topical exposure)
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig,
Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC.
Volume(issue)/page/year: 35,401,1895
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - hematuria
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 182,118,1936
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 247 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig,
Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC.
Volume(issue)/page/year: 35,401,1895
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1060 mg/kg/13W-C
TOXIC EFFECTS :
Behavioral - food intake (animal)
Blood - changes in spleen
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 10,671,1972
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 34 gm/kg/50D-I
TOXIC EFFECTS :
Blood - other changes
Nutritional and Gross Metabolic - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(3),68,1979
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 100 ug/plate
REFERENCE :
NTPTB* NTP Technical Bulletin. (National Toxicology Program, Landow Bldg.
3A-06, 7910 Woodmont Ave., Bethesda, MD 20205) Volume(issue)/page/year:
JAN1982
TYPE OF TEST : Gene conversion and mitotic recombination
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 2 umol/L
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
Volume(issue)/page/year: 86,155,1995
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Hydroxylamine, O-phenethyl-, maleate
| 96651-33-1 |
Hydroxylamine, O-(2-phenoxyethyl)-
| 73941-29-4 |
Hydroxylamine, N-phenyl-
| 100-65-2 |
Hydroxylamine, N-(p-(phenylazo)phenyl)-
| 6530-27-4 |
Hydroxylamine, N-phenylazophenyl-, hydrochloride
| 6530-27-4 |
Hydroxylamine, O,O'-(m-phenylenedimethylene)di-,dihydrochloride
| 30777-80-1 |
Hydroxylamine, O,O'-(o-phenylenedimethylene)di-,dihydrochloride
| 30777-79-8 |
Hydrazine,1-(2-methoxyisonicotinoyl)-2-(2-methylisonicotinoyl)-
| 30777-79-8 |
Hydroxylamine, O,O'-(p-phenylenedimethylene)di-,dihydrochloride
| 30777-81-2 |
Hydroxylamine, O-(3-phenylpropyl)-, hydrochloride
| 73941-30-7 |
Hydroxylamine, N-(p-(phenylthio)phenyl)-
| 21229-99-2 |
Hydroxylamine, N-(p-styrylphenyl)-, (E)
| 60462-51-3 |
Hydroxylamine, sulfate (21)
| 10039-54-0 |
Hydroxylamine-O-sulfonic acid
| 2950-43-8 |
Hydroxylamine-O-sulfonic acid,N-acetyl-N-(4-biphenylyl)-
| 2950-43-8 |
Hydroxylamine-O-sulfonic acid,N-acetyl-N-(2-phenanthrenyl)-, potassium salt
| 41935-81-3 |
Hydroxylamine-O-sulfonic acid,N-(4-butoxyphenylacetyl)-, pyridine salt
| 77372-66-8 |
Hydroxylamine-O-sulfonic acid,N-(9-chloro-4,5-dihydro-2-(2-naphthalenyl)-6H-imidazo(4,5,1-ij)quinolin-6-ylidene)-, potassium salt
| 134601-10-8 |
Hydrazine, (p-methoxy-alpha-methylbenzyl)-, oxalate
| 75333-11-8 |
Hydroxylamine-O-sulfonic acid,N-(9-chloro-4,5-dihydro-2-phenyl-6H-imidazo(4,5,1-ij)quinolin-6-ylidene)-, potassium salt
| 134601-13-1 |
Hydroxylamine-O-sulfonic acid,N-(9-chloro-4,5-dihydro-2-(phenylmethyl)-6H-imidazo(4,5,1-ij) quinolin-6-ylidene)-, potassium salt
| 134601-06-2 |
Hydroxylamine-O-sulfonic acid,N-(9-chloro-2-(1-ethylpropyl)-4,5-dihydro-6H-imidazo(4,5,1-ij) quinolin-6-ylidene)-, potassium salt
| 134601-07-3 |
Hydroxylamine-O-sulfonic acid,N-(9-chloro-2-(3-furanyl)-4,5-dihydro-6H-imidazo(4,5,1-ij) quinolin-6-ylidene)-, potassium salt
| 134601-11-9 |
Hydroxylamine-O-sulfonic acid, N-(2-naphthoyl)-,pyridine salt
| 77372-69-1 |
Hydroxylamine, N-(1,2,3,4-tetrahydro-2-naphthyl)-,hydrochloride,(+-)-
| 90874-76-3 |
Hydroxylamine, N-thenyl-, hydrochloride
| 73941-31-8 |
Hydroxylamine, N-(m-tolyl)-
| 620-25-7 |
Hydroxylamine, N-o-tolyl-
| 611-22-3 |
Hydroxylamine, N-(p-tolyl)-
| 623-10-9 |
Hydrazine, 1-(p-methoxy-alpha-methyl)phenethyl-
| 1743-42-6 |
Hydroxylamine, N-(4-(o-tolylazo)-o-tolyl)-
| 84249-59-2 |
Hydroxylamine, O-(m-(trifluoromethyl)benzyl)-,hydrochloride
| 15256-07-2 |
Hydroxylamine, O-(3,4,5-trimethoxybenzyl)-,hydrochloride
| 2173-27-5 |
Hydroxylamine, O-(2-(3,4,5-trimethoxyphenyl)ethyl)-,hydrochloride
| 2173-27-5 |
Hydroxylamine, N-(2,3-xylyl)-
| 3096-62-6 |
Hydroxylamine, N-(2,5-xylyl)-
| 3096-64-8 |
Hydroxylamine, N-(2,6-xylyl)-
| 3096-63-7 |
Hydroxylamine, N-(3,4-xylyl)-
| 43192-07-0 |
Hydroxypropyl cellulose
| 9004-64-2 |
N-Hydroxypropyldiethylenetriamine
| 1331-27-7 |
Hydrazine, 1-(o-methoxy-alpha-methylphenethyl)-,hydrochloride
| 102571-01-7 |
Hydroxypropyl methylcellulose
| 9004-65-3 |
Hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)car bonyl)- 2-methoxy-24-methyl-
| 88899-56-3 |
Hygrolytin
| 53988-66-2 |
Hygrophila quadrivulvis Nees, extractSUBSTANCE DEFINITION :Plant belonging to the family AcanthaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,487,1984
| 53988-66-2 |
Hygroscopin A
| 1403-77-6 |
Hygroscopin B
| 1403-78-7 |
Hygrostatin
| 71767-91-4 |
Hymenaea courbaril L., leaf and stem extractSUBSTANCE DEFINITION :Plant belonging to the family CaesalpiniaceaeREFERENCE :JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of GreatBritain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-Volume(issue)/page/year: 16,115,1964
| 71767-91-4 |
Hymenoxys odorata, ground plant less rootsSUBSTANCE DEFINITION :Plant belonging to the family Compositae (sunflower)REFERENCE :SOVEA7 Southwestern Veterinarian. (College of Veterinary Medicine, Texas A& M Univ., College Station, TX 77843) V.1- 1948-
| 71767-91-4 |
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