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MSDS  : Adipic acid
CAS  : 124-04-9
SYNONYMS  : * Acifloctin * Acinetten * Adilactetten * Adipic acid * Adipinic acid * 1,4-Butanedicarboxylic acid * Hexanedioic acid * 1,6-Hexanedioic acid * Kyselina adipova * Molten adipic acid
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AU8400000
CHEMICAL NAME : Adipic acid
CAS REGISTRY NUMBER : 124-04-9
BEILSTEIN REFERENCE NO. : 1209788
REFERENCE : 4-02-00-01956 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C6-H10-O4
MOLECULAR WEIGHT : 146.16
WISWESSER LINE NOTATION : QV4VQ
COMPOUND DESCRIPTOR : Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Acifloctin
* Acinetten
* Adilactetten
* Adipic acid
* Adipinic acid
* 1,4-Butanedicarboxylic acid
* Hexanedioic acid
* 1,6-Hexanedioic acid
* Kyselina adipova
* Molten adipic acid

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,315,1986

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >11 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 48(9),72,1983

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 275 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - other changes
Blood - hemorrhage
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 5,759,1957

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1900 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 5,759,1957

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 680 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Blood - hemorrhage
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 5,759,1957

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >11 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 48(9),72,1983

*** REVIEWS ***

ACGIH TLV-TWA 5 mg/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-RUSSIA:STEL 4 mg/m3 JAN 1993

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84427
No. of Facilities: 1068 (estimated)
No. of Industries: 21
No. of Occupations: 42
No. of Employees: 14846 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84427
No. of Facilities: 6259 (estimated)
No. of Industries: 54
No. of Occupations: 66
No. of Employees: 140635 (estimated)
No. of Female Employees: 77996 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Negative: Cell transform.-SA7/SHE; TRP reversion

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Adipanilic acid, 4'-sulfanilyl- 143680-74-4
Alanine, 3-((alpha,alpha-diphenylpiperonyl)thio)-, L- 35959-94-5
Alanine, 3,3'-diselenodi- 1464-43-3
Alanine, 3,3'-diselenodi-, D- 26932-45-6
Alanine, 3,3'-diselenodi-, DL- 2897-21-4
Alanine, 3,3'-diselenodi-, L- 29621-88-3
Alanine, 3,3'-diselenodi-, meso- 13900-89-5
Alanine, N-(dithiocarboxy)-, disodium salt 75808-41-2
Alanine, N-(dithiocarboxy)-3-phenyl-, L-, disodiumsalt 54872-77-4
Alanine, N-(dithiocarboxy)-, L-, zinc salt, dihydrate 54872-77-4
beta-Alanine, N,N'-(1,2-ethanediyl)bis(N-nitro- 10526-63-3
Adenosine, 2',3'-dideoxy-2'-fluoro- 110143-05-0
Adipic acid 124-04-9
Alanine,N-(6-(ethylamino)-1,4-dihydro-4-oxo-1,3,5-triazin-2-yl)-2-methyl- 36576-44-0
beta-Alanine,N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)- 104571-64-4
Alanine, 3-ethylthiocarbamoyl-, L- 4909-58-4
beta-Alanine, 2-fluoro-, hydrochloride 867-84-5
Alanine, 3-(m-fluorophenyl)- 456-88-2
Alanine, 3-(o-fluorophenyl)- 325-69-9
Alanine, 3-(p-fluorophenyl)- 60-17-3
Alanine, 3-(p-fluorophenyl)-, DL- 51-65-0
Alanine, N-((p-fluorophenyl)carbamoyl)-2-methyl-,methyl ester 70974-14-0
Alanine,N-(((4-fluoro-3-(trifluoromethyl)phenyl)amino)carbonyl)-2-methyl-, methyl ester 92668-50-3
Adipic acid, pyrolyzate 92668-50-3
Alanine, 3-(3-formyl-4-methoxyphenyl)-,hydrochloride, DL- 16277-16-0
Alanine, N-(2-furanylcarbonyl)-,(3-(5-nitro-2-furanyl)-2-propenylidene)hydrazide, DL- 39978-20-6
Alanine, N-(2-furoyl)-N-(2,6-xylyl)-, methyl ester,DL- 57646-30-7
Alanine, mixed with glucose 57646-30-7
Alanine, N-L-gamma-glutamyl-3-(methylenecyclopropyl)- 502-37-4
D-Alanine, N-(N(sup 6)-(N(sup2)-glycyl-L-glutaminyl)-D-lysyl)-, dihydrate 128593-14-6
Alanine, N-hydrocinnamoyl-3-phenyl-, potassium salt,D- 65277-77-2
Alanine, N-hydrocinnamoyl-3-phenyl-, potassium salt,L- 65277-76-1
Alanine, 3-(3-hydroxyanthraniloyl)- 484-78-6
Alanine, 3-(3-hydroxyanthraniloyl)-, L- 606-14-4
Adipic acid, 2-(3-acetamido-2,4,6-triiodobenzyl)- 10590-22-4
Alanine, 3-(3-hydroxyanthraniloyl)-, nitrosated 10590-22-4
Alanine, 3-(5-hydroxy-3-benzo(b)thienyl)- 24358-04-1
L-Alanine, N-(2-hydroxybenzoyl)- 5853-90-7
beta-Alanine, N-(4-hydroxybutyl)-N-nitroso-, methylester, acetate 79448-03-6
Alanine, N-(4-hydroxy-3,5-diiodophenethyl)-N-methyl-,beta- 79448-03-6
beta-Alanine,N-(2-hydroxy-3,3-dimethyl-1-oxo-4-(phosphonoxy)butyl)-, calcium salt (1:1), (R)- 55816-28-9
Alanine,3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-, L- 6893-02-3
beta-Alanine, N-(hydroxymethyl)-N-nitroso-, methylester, acetate 70103-81-0
Alanine,N-((8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-, (-)- 4825-86-9
L-Alanine,gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl- 35597-43-4
Adipic acid, compd. with 3-(2-aminoethyl)indol-5-ol 13425-34-8
L-Alanine,gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-, monosodium salt 71048-99-2
beta-Alanine, N-((2-hydroxyphenyl)phenylmethylene)-,monosodium salt 62665-73-0
Alanine, 3-(p-hydroxyphenyl)-N-(p-tolylsulfonyl)-,cyanomethyl ester, L- 64187-18-4
Alanine,N-((1-(1H-indol-3-ylmethyl)-4-piperidinyl)carbonyl)-,ethyl ester, monohydrochloride 64187-18-4

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