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MSDS  : Alanine, 3-(p-fluorophenyl)-
CAS  : 60-17-3
SYNONYMS  : * p-Fluorophenylalanine * 4-Fluorophenylalanine * Phenylalanine, 4-fluoro-
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AY6310000
CHEMICAL NAME : Alanine, 3-(p-fluorophenyl)-
CAS REGISTRY NUMBER : 60-17-3
LAST UPDATED : 199709
DATA ITEMS CITED : 15
MOLECULAR FORMULA : C9-H10-F-N-O2
MOLECULAR WEIGHT : 183.20
WISWESSER LINE NOTATION : QVYZ1R DF
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* p-Fluorophenylalanine
* 4-Fluorophenylalanine
* Phenylalanine, 4-fluoro-

*** HEALTH HAZARD DATA ***

** MUTATION DATA **

TYPE OF TEST : DNA damage
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 1 mmol/L
REFERENCE :
JOBAAY Journal of Bacteriology. (American Soc. for Microbiology, 1913 I
St., NW, Washington, DC 20006) V.1- 1916- Volume(issue)/page/year:
96,939,1968

TYPE OF TEST : DNA inhibition
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 1 mmol/L
REFERENCE :
JOBAAY Journal of Bacteriology. (American Soc. for Microbiology, 1913 I
St., NW, Washington, DC 20006) V.1- 1916- Volume(issue)/page/year:
96,939,1968

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 12,349,1971

TYPE OF TEST : Sex chromosome loss and nondisjunction
TEST SYSTEM : Mold - Neurospora crassa
DOSE/DURATION : 1 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 167,35,1986

TYPE OF TEST : Gene conversion and mitotic recombination
TEST SYSTEM : Yeast - Saccharomyces cerevisiae
DOSE/DURATION : 500 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 53,248,1978

TYPE OF TEST : Sex chromosome loss and nondisjunction
TEST SYSTEM : Yeast - Saccharomyces cerevisiae
DOSE/DURATION : 300 mg/L
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing
Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
Volume(issue)/page/year: 31,97,1979

TYPE OF TEST : Sex chromosome loss and nondisjunction
TEST SYSTEM : Mold - Aspergillus nidulans
DOSE/DURATION : 36 mg/L
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing
Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
Volume(issue)/page/year: 31,81,1979

TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Human HeLa cell
DOSE/DURATION : 200 umol/L
REFERENCE :
ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 92,211,1975

TYPE OF TEST : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 100 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 164,117,1986

TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 5 mmol/L
REFERENCE :
ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 89,431,1974

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Positive: Aspergillus-aneuploidy; N
crassa-aneuploidy

EPA GENETOX PROGRAM 1988, Positive: S cerevisiae gene conversion

EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-forward mutation; S
cerevisiae-aneuploidy

EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-reversion

EPA GENETOX PROGRAM 1988, Negative: Aspergillus-recombination


*** END OF RECORD ***
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NAMECAS
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Alanine, 3-((alpha,alpha-diphenylpiperonyl)thio)-, L- 35959-94-5
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Alanine, 3,3'-diselenodi-, D- 26932-45-6
Alanine, 3,3'-diselenodi-, DL- 2897-21-4
Alanine, 3,3'-diselenodi-, L- 29621-88-3
Alanine, 3,3'-diselenodi-, meso- 13900-89-5
Alanine, N-(dithiocarboxy)-, disodium salt 75808-41-2
Alanine, N-(dithiocarboxy)-3-phenyl-, L-, disodiumsalt 54872-77-4
Alanine, N-(dithiocarboxy)-, L-, zinc salt, dihydrate 54872-77-4
beta-Alanine, N,N'-(1,2-ethanediyl)bis(N-nitro- 10526-63-3
Adenosine, 2',3'-dideoxy-2'-fluoro- 110143-05-0
Adipic acid 124-04-9
Alanine,N-(6-(ethylamino)-1,4-dihydro-4-oxo-1,3,5-triazin-2-yl)-2-methyl- 36576-44-0
beta-Alanine,N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)- 104571-64-4
Alanine, 3-ethylthiocarbamoyl-, L- 4909-58-4
beta-Alanine, 2-fluoro-, hydrochloride 867-84-5
Alanine, 3-(m-fluorophenyl)- 456-88-2
Alanine, 3-(o-fluorophenyl)- 325-69-9
Alanine, 3-(p-fluorophenyl)- 60-17-3
Alanine, 3-(p-fluorophenyl)-, DL- 51-65-0
Alanine, N-((p-fluorophenyl)carbamoyl)-2-methyl-,methyl ester 70974-14-0
Alanine,N-(((4-fluoro-3-(trifluoromethyl)phenyl)amino)carbonyl)-2-methyl-, methyl ester 92668-50-3
Adipic acid, pyrolyzate 92668-50-3
Alanine, 3-(3-formyl-4-methoxyphenyl)-,hydrochloride, DL- 16277-16-0
Alanine, N-(2-furanylcarbonyl)-,(3-(5-nitro-2-furanyl)-2-propenylidene)hydrazide, DL- 39978-20-6
Alanine, N-(2-furoyl)-N-(2,6-xylyl)-, methyl ester,DL- 57646-30-7
Alanine, mixed with glucose 57646-30-7
Alanine, N-L-gamma-glutamyl-3-(methylenecyclopropyl)- 502-37-4
D-Alanine, N-(N(sup 6)-(N(sup2)-glycyl-L-glutaminyl)-D-lysyl)-, dihydrate 128593-14-6
Alanine, N-hydrocinnamoyl-3-phenyl-, potassium salt,D- 65277-77-2
Alanine, N-hydrocinnamoyl-3-phenyl-, potassium salt,L- 65277-76-1
Alanine, 3-(3-hydroxyanthraniloyl)- 484-78-6
Alanine, 3-(3-hydroxyanthraniloyl)-, L- 606-14-4
Adipic acid, 2-(3-acetamido-2,4,6-triiodobenzyl)- 10590-22-4
Alanine, 3-(3-hydroxyanthraniloyl)-, nitrosated 10590-22-4
Alanine, 3-(5-hydroxy-3-benzo(b)thienyl)- 24358-04-1
L-Alanine, N-(2-hydroxybenzoyl)- 5853-90-7
beta-Alanine, N-(4-hydroxybutyl)-N-nitroso-, methylester, acetate 79448-03-6
Alanine, N-(4-hydroxy-3,5-diiodophenethyl)-N-methyl-,beta- 79448-03-6
beta-Alanine,N-(2-hydroxy-3,3-dimethyl-1-oxo-4-(phosphonoxy)butyl)-, calcium salt (1:1), (R)- 55816-28-9
Alanine,3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-, L- 6893-02-3
beta-Alanine, N-(hydroxymethyl)-N-nitroso-, methylester, acetate 70103-81-0
Alanine,N-((8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-, (-)- 4825-86-9
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Adipic acid, compd. with 3-(2-aminoethyl)indol-5-ol 13425-34-8
L-Alanine,gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-, monosodium salt 71048-99-2
beta-Alanine, N-((2-hydroxyphenyl)phenylmethylene)-,monosodium salt 62665-73-0
Alanine, 3-(p-hydroxyphenyl)-N-(p-tolylsulfonyl)-,cyanomethyl ester, L- 64187-18-4
Alanine,N-((1-(1H-indol-3-ylmethyl)-4-piperidinyl)carbonyl)-,ethyl ester, monohydrochloride 64187-18-4

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