*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NO7190000
CHEMICAL NAME : Iron, (nitrilotriacetato)-
CAS REGISTRY NUMBER : 16448-54-7
LAST UPDATED : 199706
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C6-H6-Fe-N-O6
MOLECULAR WEIGHT : 243.98
WISWESSER LINE NOTATION : OV1N1VO&1VO &-FE-
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Acetic acid, nitrilotri-, iron(III) chelate
* Ferric nitrilotriacetate
* Iron, (N,N-bis(carboxymethyl)glycinato(3-)-N,O,O',O'')-, (T-4)-
* Iron nitrilotriacetate
* Iron-nitrilotriacetate chelate
* Iron(3+) nta
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 52422 ug/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Kidney, Ureter, Bladder - hematuria
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 59,37,1989
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 341 mg/kg/13D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in leukocyte (WBC) count
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other oxidoreductases
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 59,37,1989
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1988 mg/kg/65D-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC)
V.61-79, 1978-87. For publisher information, see JNCIEQ.
Volume(issue)/page/year: 76,107,1986
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 566 mg/kg/12W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
47,1867,1987
** MUTATION DATA **
TYPE OF TEST : DNA damage
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 65530 ug/kg
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year:
54,95,1990
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 1 mmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 14,107,1993
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 2 mmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
41,1628,1981
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 1 mmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 14,107,1993
TYPE OF TEST : Mutation in mammalian somatic cells
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 50 mg/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 11,257,1990
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
|
2-Indolinone,1-methyl-3-(5-phenyl-1,3,4-oxadiazol-2-ylimino)-
| 84640-83-5 |
|
Iron,bis(1,2-benzenediamine-N,N')(ethanedioato(2-)-O,O')-,(OC-6-22)-
| 75079-27-5 |
|
Iron,bis(1,2-ethanediamine-N,N')(ethanedioato(2-)-O,O')-,(OC-6-22)-
| 67537-95-5 |
|
Iron(2+), bis(1,2-ethanediamine-N,N')-,(T-4)-tetrakis(thiocyanato-N)mercurate(2-) (1:1),homopolymer
| 80732-92-9 |
|
Iron(II), bis(N-ethylidenethreoninato)diaquo-
| 15339-50-1 |
|
Iron, bis(mu-(methanethiolato))tetranitrosyldi-,(Fe-Fe)
| 16071-96-8 |
|
Iron,bis(3-methylbenzenamine)(ethanedioato(2-)-O,O')-
| 74910-19-3 |
|
Iron,bis(3-((phenylamino)methyl)-2(3H)-benzoxazolone-N(supN(sup 3),O(sup 2))bis (thiocyanato-N))-
| 82489-95-0 |
|
Iron,bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N(sup 3),O(sup 4))-
| 85187-45-7 |
|
Iron, (1,3-butadiene)tricarbonyl-
| 12078-32-9 |
|
Iron carbonyl
| 13463-40-6 |
|
2-Indolinone,5-methyl-3-(5-phenyl-1,3,4-oxadiazol-2-ylimino)-
| 84640-91-5 |
|
Iron(II) chloride (12)
| 7758-94-3 |
|
Iron(3+) chloride, hexahydrate
| 10025-77-1 |
|
Iron(2+) chloride, tetrahydrate
| 13478-10-9 |
|
Iron dextran glycerol glycoside
| 13478-10-9 |
|
Iron-dextrin complex
| 9004-51-7 |
|
Iron, diammine(ethanedioato(2-)-O,O')-, (T-4)-
| 67619-85-6 |
|
Iron, dicarbonyl-pi-cyclopentadienyl-, iodide
| 12078-28-3 |
|
Iron, (dihydrogen3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-))-hydroxy-
| 15489-90-4 |
|
Iron(3+),(N1-(3-(dimethylsulfonio)propyl)bleomycinamidato)-
| 72028-04-7 |
|
Iron dustSUBSTANCE DEFINITION :Iron dust from open hearth furnace; dust contained 52% ironREFERENCE :85AGAF "Effects and Dose-response Relationships of Toxic Metals, Proceedingsfrom an International Meeting, Tokyo, 1974," Nordberg, G.F., ed., Amsterdam,Elsevier Science Pub. B.V., 1976 Volume(issue)/page/year: -,480,1976
| 72028-04-7 |
|
2-Indolinone, 3-(2-nitro-1-nitrosoethylidene)-
| 72028-04-7 |
|
Iron, (ethanedioato(2-)-O,O')bis(1-butanamine)-
| 80660-60-2 |
|
Iron, (ethanedioato(2-)-O,O')bis(methanamine)-
| 80660-61-3 |
|
Iron,(ethanedioato(2-)-O,O')bis(3-methoxybenzenamine-N)-
| 80660-63-5 |
|
Iron,(ethanedioato(2-)-O,O')bis(4-methoxybenzenamine-N)-
| 80660-63-5 |
|
Iron,(ethanedioato(2-)-O,O')bis(1-methylpiperazine-N(sup1),N(sup 4))-
| 75079-26-4 |
|
Iron,(ethanedioato(2-)-O,O')bis(1,10-phenanthroline-N(sup1),N(sup 10))-, (OC-6-22)-
| 14783-55-2 |
|
Iron,(ethanedioato(2-)-O,O')bis(3-((phenylamino)methyl)-2(3H)-benzoxazolone- N(sup N(sup 3),O(sup 2))-
| 82489-96-1 |
|
Iron,(ethanedioato(2-)-O,O')bis(1-phenylpiperazine-N(sup1),N(sup 4))-
| 75079-25-3 |
|
Iron, (ethanedioato(2-)-O,O')bis(pyridine1-oxide-O)-, (T-4)-
| 74167-27-4 |
|
Iron, (ethanedioato(2-)-O,O')tetrakis(piperidine)-,(OC-6-22)-
| 80660-62-4 |
|
2-Indolinone, 3-(phenylimino)-
| 33828-98-7 |
|
Iron fluoride
| 7783-50-8 |
|
Iron, (hydrogen(ethylenedinitrilo)tetraacetato)-
| 17099-81-9 |
|
Iron(III)hydroxide-polymaltose
| 17099-81-9 |
|
Iron, ion(Fe 2+)
| 15438-31-0 |
|
Iron(1+), (isonicotinic acid hydrazide)-, sulfate,dihydrate
| 15438-31-0 |
|
Iron magnesium manganese oxide
| 37187-66-9 |
|
Iron manganese zinc oxide
| 12645-49-7 |
|
Iron nickel powderSUBSTANCE DEFINITION :Composed of 68.5% Fe, 2.9% Ni, 0.93% C, and 1.1% OREFERENCE :ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-1990- Volume(issue)/page/year: 11,692,1992
| 12645-49-7 |
|
Iron nickel zinc oxide
| 12645-50-0 |
|
Iron(II) nitrate hexahydrate (126)
| 13520-68-8 |
|
2-Indolinone, 3-(5-phenyl-1,3,4-oxadiazol-2-ylimino)-
| 84640-80-2 |
|
Iron(III) nitrate, nonahydrate (139)
| 7782-61-8 |
|
Iron, (nitrilotriacetato)-
| 16448-54-7 |
|
Iron, nitrosotris(dimethyldithiocarbamato)-, mixedwith bis(dimethylthiocarbamoyl)disulfideSUBSTANCE DEFINITION :58.5% main component, 6.5% secondary componentREFERENCE :NTIS** National Technical Information Service. (Springfield, VA 22161)Formerly U.S. Clearinghouse for Scientific & Technical Information.
| 16448-54-7 |
|
Iron ore, respirable dust
| 16448-54-7 |
|
Iron(III) oxide
| 1309-37-1 |
|
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