RTECS NUMBER : NR0195000
CHEMICAL NAME : Isocyanic acid, triester with
1,3,5-tris(6-hydroxyhexyl)biuret
CAS REGISTRY NUMBER : 4035-89-6
BEILSTEIN REFERENCE NO. : 2192715
LAST UPDATED : 199710
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C23-H38-N6-O5
MOLECULAR WEIGHT : 478.67
SYNONYMS/TRADE NAMES :
* Hexamethylene diisocyanate biuret
* Imidodicarbonic diamide, N,N',2-tris(6-isocyanatohexyl)-
* Tris(isocyanatohexyl)biuret
* Tris(6-isocyanatohexyl) biuret
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 19800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0528545
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 91 mg/m3/4H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression
Lungs, Thorax, or Respiration - other changes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
64,423,1982
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >15800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0528545
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2792
No. of Facilities: 23 (estimated)
No. of Industries: 3
No. of Occupations: 4
No. of Employees: 1259 (estimated)