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MSDS  : KL-3R3 SUBSTANCE DEFINITION : Composed of sodium citrate, citric acid, dextrose, monobasic sodium phosphate, and adenine REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
CAS  : 9039-53-6
SYNONYMS  : * Anticoagulant citrate phosphate dextrose adenine solution
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OC2026900
CHEMICAL NAME : KL-3R3
SUBSTANCE DEFINITION :
Composed of sodium citrate, citric acid, dextrose, monobasic sodium
phosphate, and adenine
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu
Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
LAST UPDATED : 199509
DATA ITEMS CITED : 2
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Anticoagulant citrate phosphate dextrose adenine solution

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 11800 uL/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu
Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
Volume(issue)/page/year: 21,1017,1993

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 210 mL/kg/4W-I
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
Nutritional and Gross Metabolic - changes in sodium
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu
Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
Volume(issue)/page/year: 21,1023,1993

*** END OF RECORD ***
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