Search   
MSDS  : 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-(cyclopropylmethyl)-6,11-dime thyl-
CAS  : 3572-80-3
SYNONYMS  : * Cyclazocine * 2-Cyclopropylmethyl-5,9-dimethyl-2'-hydroxy-6,7-benzomorphan * 3-Cyclopropylmethyl-6(eq),11(ax)-dimethyl-2,6-methano-3-benzazocin-8-ol * 3-(Cyclopropylmethyl)1-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3 -benzazocin-8-ol * 2-Cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan * 2,6-Methano-3-benzazocin-8-ol, 3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl- * NIH 7981 * NSC-107429 * WIN 20740
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : PB8585000
CHEMICAL NAME : 2,6-Methano-3-benzazocin-8-ol,
1,2,3,4,5,6-hexahydro-3-(cyclopropylmethyl)-6,11-dime
thyl-
CAS REGISTRY NUMBER : 3572-80-3
LAST UPDATED : 199012
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C18-H25-N-O
MOLECULAR WEIGHT : 271.44
WISWESSER LINE NOTATION : T C666 A KN&TTJ A1 B1 EQ K1- AL3TJ
COMPOUND DESCRIPTOR : Drug
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Cyclazocine
* 2-Cyclopropylmethyl-5,9-dimethyl-2'-hydroxy-6,7-benzomorphan
* 3-Cyclopropylmethyl-6(eq),11(ax)-dimethyl-2,6-methano-3-benzazocin-8-ol
* 3-(Cyclopropylmethyl)1-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3
-benzazocin-8-ol
* 2-Cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan
* 2,6-Methano-3-benzazocin-8-ol,
3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-
* NIH 7981
* NSC-107429
* WIN 20740

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 143,141,1964

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 165,112,1967

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD
Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970-
Volume(issue)/page/year: 17,255,1977

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,2009,1976

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 28 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 165,112,1967

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE : 13 mg/kg
SEX/DURATION : female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Fertility - abortion
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
31,534,1975

*** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-8-methoxy-2-methyl-, oxalate 76777-11-2
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-(3-methyl-2-butenyl)-,hydrochloride 76777-07-6
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-(3-methyl-2-butenyl)-,oxalate 76777-27-0
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-methyl-, hydrobromide 76776-97-1
1,5-Methano-3-benzazocine,1,2,3,4,5,6-hexahydro-3-methyl-, hydrochloride 36065-74-4
Methanediamine, N,N'-dimethyl-N,N'-dinitro- 13232-00-3
2,6-Methano-3-benzazocine,1,2,3,4,5,6-hexahydro-3-methyl-, hydrochloride 23007-86-5
2,6-Methano-3-benzazocine,1,2,3,4,5,6-hexahydro-6-methyl-3-phenethyl-,hydrochloride 23007-86-5
2,6-Methano-3-benzazocine,1,2,3,4,5,6-hexahydro-8-nitro-3,6,11-trimethyl-,hydrochloride 101834-41-7
1,6-Methano-2-benzazocine, 1,2,3,4,5,6-hexahydro-,oxalate 76777-24-7
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-phenethyl-, hydrochloride 76776-99-3
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-phenethyl-, oxalate 101771-79-3
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-propyl-, hydrochloride 76777-03-2
1,6-Methano-2-benzazocine,1,2,3,4,5,6-hexahydro-2-propyl-, oxalate 76777-01-0
2,6-Methano-3-benzazocine,1,2,3,4,5,6-hexahydro-3,6,11-trimethyl- 53424-43-4
2,6-Methano-3-benzazocine,1,2,3,4,5,6-hexahydro-3,6,11-alpha-trimethyl-,hydrochloride 49822-16-4
Methanediamine, N,N'-dinitro- 14168-44-6
2,6-Methano-3-benzazocinium,1,2,3,4,5,6-hexahydro-6,11-dimethyl-8-hydroxy-N-phenethyl- N-(2-propenyl)-, bromide 63869-49-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-((2,2-dimethylcyclo propyl)methyl)-, hydrochloride 74411-68-0
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-allyl-6,11-dimethyl- 7619-35-4
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-allyl-6-ethyl-11-methyl- 6654-31-5
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(p-aminophenethyl)-6,11-alpha-dimethyl- 63869-50-1
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-butyl-6,11-alpha-dimethyl-,hydrobromide 63903-60-6
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6-butyl-3-methyl-, alpha-(+-) 64023-89-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(2-chloro-2-propenyl)-6,11-dimethyl- 63905-04-4
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(3-chloro-2-propenyl)-6,11-dimethyl-, (Z)- 3769-03-7
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(cyanomethyl)-6,11-dimethyl- 3639-69-8
Methanediamine, 1,1-diphenyl-N,N,N',N'-tetramethyl- 19111-89-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(cyclobutylmethyl)-6,11-dimethyl- 25161-57-3
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(cyclobutylemthyl)-6-ethyl-1-methyl- 63869-51-2
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(cyclopentylmethyl)-6,11-dimethyl- 4490-59-9
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(cyclopropylmethyl)-6,11-dimethyl- 3572-80-3
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-cyclopropylmethyl-6,11-alpha-dimethyl-, 63903-61-7
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(3,3-dichloro-2-propenyl)-6,11-dimethyl 3639-67-6
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3-(3,3-dichloro-2-propenyl)-6-ethyl-11-methyl- 3639-68-7
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-diethyl-3-(3-furanylmethyl)-, hydrochloride, (2a,6a,11R*)-, (+-)- 61849-15-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-diethyl-3-methyl-,alpha-(+-)- 61849-15-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-diethyl-3-methyl-,beta-(+-)- 27507-45-5
Methanediamine, N,N,N',N'-tetramethyl- 51-80-9
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-alpha-diethyl-3-methyl-,acetate (ester), hydrochloride 63869-52-3
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-alpha-diethyl-3-methyl-,hydrochloride 63903-62-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-alpha-diethyl-3-methyl-,hydrochloride, (+) 10286-45-0
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-beta-diethyl-3-methyl-,hydrochloride 63903-63-9
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-alpha-diethyl-3-phenethyl-, hydrobromide 63915-46-8
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-dimethyl- 16808-63-2
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3,6-dimethyl-, (+-)- 20649-36-9
2,6-Methano-3-benzazocin-11-beta-ol,1,2,3,4,5,6-hexahydro-3,6-dimethyl-, acetate (ester),hydrobromide 63869-53-4
2,6-Methano-3-benzazocin-1-ol,1,2,3,4,5,6-hexahydro-3,6-dimethyl-, acetate(ester),hydrochloride 63869-54-5
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-3,6-dimethyl-11-ethyl-,alpha-(+-)- 28623-77-0
Methanediamine, N,N,N',N'-tetramethyl-, ethanedioate 132050-00-1

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com