Search   
MSDS  
:
 4,7-Methanoindan,
1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-
CAS  
:
 57-74-9
SYNONYMS  
:
 * Aspon-chlordane
* BELT
* CD 68
* Chloordaan
* Chlordan
* Chlordane
* Chlorindan
* Chlor KIL
* Chlorodane
* Chlortox
* Clordan
* Clordano
* Cortilan-neu
* Dichlorochlordene
* Dowchlor
* ENT 9,932
* ENT 25,552-X
* HCS 3260
* Kilex lindane
* Kypchlor
* Latka 1068
* M 140
* 4,7-Methano-1H-indene,
1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-
* NCI-C00099
* Octachlor
* Octachlorodihydrodicyclopentadiene
* 1,2,4,5,6,7,8,8-Octahydro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindan
* 1,2,4,5,6,7,8,8-Octachlor-2,3,3a,4,7,7a-hexahydro-4,7-methanoindane
* 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene
* 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene
* 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-hexahydro-4,7-methylene indane
* Octachloro-4,7-methanohydroindane
* Octachloro-4,7-methanotetrahydroindane
* 1,2,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane
* 1,2,4,5,6,7,8,8-Octachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indaan
* 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane
* 1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane
* 1,2,4,5,6,7,8,8-Octachlor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indan
* Octa-klor
* Oktaterr
* OMS 1437
* Ortho-klor
* 1,2,4,5,6,7,8,8-Ottochloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indano
* RCRA waste number U036
* SD 5532
* Shell SD-5532
* Starchlor
* Synklor
* TAT chlor 4
* Termi-ded
* Topichlor 20
* Topiclor
* Topiclor 20
* Toxichlor
* Unexan-koeder
* Velsicol 1068

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ 4,7-Methanoindan,1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro- 57-74-9 ]
Suppliers:   
Not Available
Buyers:  
Not Available
                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB9800000
CHEMICAL NAME           : 4,7-Methanoindan,
                          1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-
CAS REGISTRY NUMBER     : 57-74-9
OTHER CAS REGISTRY NOS. : 39400-80-1
                          53637-13-1
BEILSTEIN REFERENCE NO. : 1915474
LAST UPDATED            : 199712
DATA ITEMS CITED        : 88
MOLECULAR FORMULA       : C10-H6-Cl8
MOLECULAR WEIGHT        : 409.76
WISWESSER LINE NOTATION : L C555 A IUTJ AG AG BG DG EG HG IG JG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Tumorigen
                          Mutagen
                          Reproductive Effector
                          Human
SYNONYMS/TRADE NAMES :
   * Aspon-chlordane
   * BELT
   * CD 68
   * Chloordaan
   * Chlordan
   * Chlordane
   * Chlorindan
   * Chlor KIL
   * Chlorodane
   * Chlortox
   * Clordan
   * Clordano
   * Cortilan-neu
   * Dichlorochlordene
   * Dowchlor
   * ENT 9,932
   * ENT 25,552-X
   * HCS 3260
   * Kilex lindane
   * Kypchlor
   * Latka 1068
   * M 140
   * 4,7-Methano-1H-indene,  
   1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-
   * NCI-C00099
   * Octachlor
   * Octachlorodihydrodicyclopentadiene
   * 1,2,4,5,6,7,8,8-Octahydro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindan
   * 1,2,4,5,6,7,8,8-Octachlor-2,3,3a,4,7,7a-hexahydro-4,7-methanoindane
   * 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene
   * 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene
   * 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-hexahydro-4,7-methylene indane
   * Octachloro-4,7-methanohydroindane
   * Octachloro-4,7-methanotetrahydroindane
   * 1,2,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane
   * 1,2,4,5,6,7,8,8-Octachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indaan
   * 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane
   * 1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane
   * 1,2,4,5,6,7,8,8-Octachlor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indan
   * Octa-klor
   * Oktaterr
   * OMS 1437
   * Ortho-klor
   * 1,2,4,5,6,7,8,8-Ottochloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indano
   * RCRA waste number U036
   * SD 5532
   * Shell SD-5532
   * Starchlor
   * Synklor
   * TAT chlor 4
   * Termi-ded
   * Topichlor 20
   * Topiclor
   * Topiclor 20
   * Toxichlor
   * Unexan-koeder
   * Velsicol 1068
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 3071 ug/kg
TOXIC EFFECTS :
   Behavioral - coma
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - nausea or vomiting
REFERENCE :
   JTCTDW Journal of Toxicology, Clinical Toxicology.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.19-    1982-  Volume(issue)/page/year:
   20,291,1983
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Liver - fatty liver degeneration
REFERENCE :
   CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public
   Health Service, Communicable Disease Center, Atlanta, GA, 1956
   Volume(issue)/page/year: -,1,1956
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 120 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Gastrointestinal - gastritis
REFERENCE :
   CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public
   Health Service, Communicable Disease Center, Atlanta, GA, 1956
   Volume(issue)/page/year: -,1,1956
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human
DOSE/DURATION           : 428 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,648,1969
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 118 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M.,
   Springfield, IL, C.C. Thomas, 1970  Volume(issue)/page/year: 2,73,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,614,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 690 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAVMA4 Journal of the American Veterinary Medical Association.  (American
   Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.48-
   1915-  Volume(issue)/page/year: 157,1835,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 343 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   32,443,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 145 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARSIM* Agricultural Research Service, USDA Information Memorandum.
   (Beltsville, MD 20705)  Volume(issue)/page/year: 20,19,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,288,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#04876
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 100 mg/m3/4H
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(4),30,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,226,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 780 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHOAX Archives of Industrial Hygiene and Occupational Medicine.  (Chicago,
   IL)  V.1-2(3), 1950.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 1,13,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 1720 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJTXAZ European Journal of Toxicology and Environmental Hygiene.  (Paris,
   France)  V.7-9, 1974-76. For publisher information, see TOERD9.
   Volume(issue)/page/year: 7,159,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 220 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,226,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DOEAAH Down to Earth.  (Dow Chemical USA, Agricultural Products Dept.,
   Midland, MI 48640) V.1-    1945-  Volume(issue)/page/year: 35,25,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 32,471,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,226,1966
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : >20 gm/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,139,1991
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 410 mg/kg/39W-C
TOXIC EFFECTS :
   Liver - other changes
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 64,614,1957
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28200 ug/m3/8H/28D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - changes in bladder weight
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 28,327,1989
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 660 mg/kg/15D-I
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Related to Chronic Data - death
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 7,197,1953
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6512 mg/kg/58W-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 7,197,1953
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5475 mg/kg/2Y-C
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), zonal
   Liver - changes in liver weight
   Related to Chronic Data - death
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 6,357,1952
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/m3/8H/90D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - changes in bladder weight
   Nutritional and Gross Metabolic - changes in calcium
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 28,327,1989
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 504 mg/kg/12W-C
TOXIC EFFECTS :
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   APTOD9 Abstracts of Papers, Society of Toxicology.  Annual Meetings.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
   Volume(issue)/page/year: 19,A99,1980
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2020 mg/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-8,1977
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3780 mg/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-8,1977
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3360 ug/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - endocrine system
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),357,1978
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 152 mg/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - immune and
   reticuloendothelial system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   62,402,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 7 mg/kg
SEX/DURATION            : female 15-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   BJPCBM British Journal of Pharmacology.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.34-    1968-  Volume(issue)/page/year:
   49,311,1973
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3040 ug/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   ENVRAL Environmental Research.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1967-  Volume(issue)/page/year: 35,204,1984
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 168 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - delayed effects
REFERENCE :
   APTOD9 Abstracts of Papers, Society of Toxicology.  Annual Meetings.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
   Volume(issue)/page/year: 19,A18,1980
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 168 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - immune and
   reticuloendothelial system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 19,23A,1979
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 3050 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 182,193,1987
 
TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Fish - not otherwise specified
DOSE/DURATION           : 54 pmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 118,61,1983
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 1 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 42,161,1977
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   52,221,1983
 
TYPE OF TEST            : Morphological transformation
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1260 mg/kg/6W
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 9,387,1988
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 343,157,1995
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 301,33,1993
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 10 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   19,369,1977

                              *** REVIEWS ***
 
   ACGIH TLV-Animal carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.5 mg/m3 (skin)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 20,45,1979

   IARC Cancer Review:Animal Limited Evidence
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,146,1987

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 53,115,1991

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 20,45,1979

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 53,115,1991

   IARC Cancer Review:Group 2B
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 53,115,1991

   TOXICOLOGY REVIEW
   CNDQA8 Cahiers de Nutrition et de Dietetique.  (Editions Meteore, 42, rue du
   Louvre, 75001 Paris, France)  V.1-    1966-  Volume(issue)/page/year:
   10(3),43,1975

   TOXICOLOGY REVIEW
   RREVAH Residue Reviews.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1962-  Volume(issue)/page/year:
   56,107,1975

   TOXICOLOGY REVIEW
   BNYMAM Bulletin of the New York Academy of Medicine.  (New York Academy of
   Medicine, 2 E. 103rd St., New York, NY 10029)  Ser 2: V.1-    1925-
   Volume(issue)/page/year: 54,413,1978

   TOXICOLOGY REVIEW
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 13,231,1978

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

   MSHA STANDARD-air:TWA 0.5 mg/m3 (skin)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,44,1971

   OSHA PEL (Gen Indu):8H TWA 0.5 mg/m3 (skin)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.5 mg/m3 (skin)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.5 mg/m3 (skin)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.5 mg/m3 (skin)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-AUSTRALIA:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin;Carcinogen JAN 1993
   
   OEL-AUSTRIA:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-BELGIUM:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin JAN 1993
   
   OEL-DENMARK:TWA 0.5 mg/m3;Skin;Carcinogen JAN 1993
   
   OEL-FINLAND;Carcinogen JAN 1993
   
   OEL-FRANCE:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-GERMANY:TWA 0.5 mg/m3;Skin;Carcinogen JAN 1993
   
   OEL-INDIA:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-RUSSIA:STEL 0.01 mg/m3;Skin JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-THAILAND:TWA 0.5 mg/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.5 mg/m3;Skin JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO CHLORDANE-air:10H CA TWA 0.5 mg/m3 (Sk)
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

                          *** STATUS IN U.S. ***
 
   ATSDR TOXICOLOGY PROFILE
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB/90/168709/AS

   EPA TSCA Section 8(d) unpublished health/safety studies
   
   On EPA IRIS database
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Chlordane, 5510
   
   NCI Carcinogenesis Bioassay (feed);clear evidence:mouse
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-8,77

   NCI Carcinogenesis Bioassay (feed);no evidence:rat
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-8,77

 
                            *** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
7,14-Methano-2H,6H-dipyrido(1,2-a1',2'-e)(1,5)diazocine, dodecahydro-6-butyl-,(R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) 75714-73-7
7,14-Methano-2H,6H-dipyrido(1,2-a1',2'-e)(1,5)diazocine, dodecahydro-, monohydriodide,(7R-(7-alpha,7a-alpha,14-alpha,14a-beta))- 51799-26-9
7,14-Methano-2H,6H-dipyrido(1,2-a1',2'-e)(1,5)diazocine, dodecahydro-6-pentyl-,(R-(R*,R*)-2,3-dihydroxybutanedioate (1:1) 75686-51-0
7,14-Methano-2H,6H-dipyrido(1,2-a1',2'-e)(1,5)diazocin-6-one, dodecahydro-, (7S-(7-alpha,7a-beta,14-alpha,14a-beta))- 82109-83-9
7,14-Methano-2H,6H-dipyrido(1,2-a1',2'-e)(1,5)diazocin-6-one, dodecahydro-, monohydrochloride,(7R-(7-alpha,7a-alpha,14-alpha,14a-beta))- 40136-09-2
Methane, fluorotrichloro- with nitromethane(99.7:0.3)SUBSTANCE DEFINITION :Contains 0.3% nitromethane in addition to freon-11REFERENCE :TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University.(Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,Japan) V.1- 1954- 40136-09-2
7,14-Methano-4H,6H-dipyrido(1,2-a1',2'-e)(1,5)diazocin-4-one, dodecahydro-, monohydrochloride,(7S-(7-alpha,7a-beta,14-alpha,14a-alpha))- 40136-09-2
5,11-Methanofuro(3,4-d)(3)benzoxonin-1,12(3H,5H)-dione, 6,6a,7,8,9,10,10a,11-octahydro-6,6a-dihydroxy-11,13-dimethyl-3-methylene-,(5R-(5R*,6S*,6aR*,10aR*,11S*,13R*))- 156980-57-3
5,11-Methanofuro(3,4-d)(3)benzoxonin-1,12(3H,5H)-dione, 6,6a,7,8,9,10,10a,11-octahydro-6,6a-dihydroxy-3,11,13-trimethyl-,(3R-(3R*,5R*,6S*,6ar*,10ar*,11S*,13R*))- 166403-10-7
1,24-Methano-1H,9H,15H-furo(3',4'10,11)(1,7)dioxacyclotetradecino(4,3-e)p yrano(2,3-i)(4)benzoxecin-6,13,15,18(3ah)-tetrone,4,5,7a,8,16,17,20,20a,24,25,26,26a-dodecahydro-8,26-dihydroxy-22,25-dimethyl-5-methoxy- 99820-21-0
1,5-Methano-11H-furo(3,2-g)pyrano(3,2-b)xanthene-3a(4H)-crotonaldehyde, 1,2,5,7-tetrahydro-8-hydroxy-alpha,2,2,11,11-pentamethyl-13-(3-methyl-2-butenyl)-4,7-dioxo-, trans- 1183-12-6
1,5-Methano-1H,3H,11H-furo(3,4-g)pyrano(3,2-b)xanthene-1-crotonic acid, 3a,4,5,7-tetrahydro-8-hydroxy-alpha,3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3- pentenyl)-7,15- dioxo-, (Z)- 2752-65-0
8,12-Methano-2H-furo(3,2-g)pyrano(2,3-a)xanthene-10a(11H)-crotonic acid, 8,9,12,14-tetrahydro-5-hydroxy-alpha,2,9,9-tetramethyl-6-(3-methyl-2-butenyl)-2-(4-m ethyl-3- pentenyl)-11,14-dioxo- 6129-34-6
2,5-Methanoindan-4-amine, hexahydro-N-benzyl-,hydrochloride 59177-71-8
2,5-Methanoindan-4-amine,hexahydro-4-(p-chlorobenzyl)-, hydrochloride 67293-83-8
2,5-Methanoindan-4-amine, hexahydro-, hydrochloride 59177-69-4
Methane, fluorotrinitro- 1840-42-2
2,5-Methanoindan-4-amine,hexahydro-4-(2-hydroxyethyl)amino-, hydrochloride 59177-73-0
2,5-Methanoindan-4-amine, hexahydro-N-methyl-,hydrochloride 59177-70-7
2,5-Methanoindan-4-amine, hexahydro-4-phenethyl-,hydrochloride 67293-84-9
4,7-Metanoindan-2,5-bis(methylamine),hexahydro-N,N'-dicyclohexyl-, dihydrochloride 63905-06-6
4,7-Methanoindan, 1,25,6-diepoxyhexahydro-, mixedisomersSUBSTANCE DEFINITION :Mixture of 70% exo isomers, 30% endo isomersREFERENCE :AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 WolfLedges Pkwy., Akron, OH 44311) V.19- 1958- 63905-06-6
4,7-Methanoindan,1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahydro- 1024-57-3
4,7-Methanoindan,1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro- 2589-15-3
4,7-Methanoindan, hexahydro-, exo- 2825-82-3
4,7-Methanoindan, hexahydro-1,8-diamino- 6818-18-4
4,7-Methanoindan,3a,4,5,6,7,7a-hexahydro-1,2:5,6-diepoxy- 81-21-0
Methanehydrazonamide,N'-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N,N-dimethyl- 56364-22-8
4,7-Methanoindan,3a,4,5,6,7,7a-hexahydro-1,2:5,6-diepoxy-, endo- 56364-22-8
4,7-Methanoindan, hexahydro-2-hydroxymethyl- 64644-36-6
2,5-Methanoindan-4-methylamine, hexahydro-N-benzyl-,maleate 59177-78-5
2,5-Methanoindan-4-methylamine,hexahydro-N,N-dimethyl-4-hydroxy-, hydrochloride,hydrate (3:3:1) 67293-85-0
2,5-Methanoindan-4-methylamine,hexahydro-4-hydroxy-N-methyl-, maleate 59177-79-6
2,5-Methanoindan-4-methylamine, hexahydro-N-methyl-,maleate 59177-76-3
4,7-Methanoindan,1,2,4,5,6,7,8,8-octachloro-2,3-epoxy-3a,4,7,7a-tetrahydro-, exo,endo- 27304-13-8
4,7-Methanoindan,1-alpha,2-alpha,4-beta,5,6,7-beta,8,8-octachloro-3a-alpha,4,7,7a-alpha- tetrahydro- 5103-71-9
4,7-Methanoindan,1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro- 57-74-9
4,7-Methanoindan,2,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-,stereoisomer 5566-34-7
Methane, iodo- 74-88-4
4,7-Methanoindan,1,2,3,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-, (Z)mixed with E-1,2,3,5,6,7,8,8-octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane (3:1) 74-88-4
2,5-Methanoindan-4-ol,hexahydro-4-(4-methyl-1-piperazinyl)methyl-,dihydrochloride 59177-82-1
4,7-Methanoindan-1-ol,3a,4,7,7a-tetrahydro-2,3-epoxy-4,5,6,7,8,8-hexachloro- 24009-06-1
4,7-Methanoindan-5(4H)-one, tetrahydro- 13380-94-4
4,7-Methanoindan,3a,4,7,7a-tetrahydro-1,2-epoxy-4,5,6,7,8,8-hexachloro- 6058-23-7
4,7-Methanoindan,3a-alpha,4,7,7a-alpha-tetrahydro-2-alpha,4-beta,5,6,7-beta,8,8-heptachloro- 14168-01-5
4,7-Methanoindan,3a-beta,4,7,7a-beta-tetrahydro-1-beta,2-alpha,4-alpha,5,6,7-alpha,8,8- octachloro- 5103-74-2
4,7-Methano-1H-inden-5-amine,octahydro-N-(cyclopropylmethyl)-, hydrochloride,(3a-alpha,4- beta,5-alpha,7-beta,7a-alpha)- 73336-07-9
4,7-Methanoindene 209-96-1
4,7-Methanoindene,1-bromo-4,5,6,7,8,8-hexachloro-3a,4,7,7a-tetrahydro- 3186-23-0
Methane, iodo-, pyrolyzate 3186-23-0

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com