Search   
MSDS  
:
 Methane, chlorofluoro-
CAS  
:
 593-70-4
SYNONYMS  
:
 * CFC 31
* Chlorofluoromethane
* FC 31
* Freon 31
* G 31
* Genetron 31
* Khladon 31
* Methylene chloride fluoride
* Monochloromonofluoromethane
* R 31
* R 31 (Refrigerant)

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PA6408000
CHEMICAL NAME           : Methane, chlorofluoro-
CAS REGISTRY NUMBER     : 593-70-4
BEILSTEIN REFERENCE NO. : 1730796
REFERENCE               : 4-01-00-00032 (Beilstein Handbook Reference)
LAST UPDATED            : 199801
DATA ITEMS CITED        : 16
MOLECULAR FORMULA       : C-H2-Cl-F
MOLECULAR WEIGHT        : 68.48
WISWESSER LINE NOTATION : G1F
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * CFC 31
   * Chlorofluoromethane
   * FC 31
   * Freon 31
   * G 31
   * Genetron 31
   * Khladon 31
   * Methylene chloride fluoride
   * Monochloromonofluoromethane
   * R 31
   * R 31 (Refrigerant)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12635 mg/m3
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (2),34,1996
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 10000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   48,A109,1979
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10000 ppm/6H/2W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
   Endocrine - other changes
   Blood - changes in spleen
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0571266
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 78 gm/kg/1Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   72,15,1984
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 pph
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 118,277,1983
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Kidney
DOSE/DURATION           : 100 umol/L
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   72,15,1984
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 pph
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 25,91,1982

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 41,229,1986

   IARC Cancer Review:Human No Adequate Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 41,229,1986

   IARC Cancer Review:Group 3
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,56,1987

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-GERMANY;Carcinogen JAN 1993
   
   OEL-HUNGARY:TWA 100 mg/m3;STEL 200 mg/m3 JAN 1993
   
   OEL-SWITZERLAND;Carcinogen JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X3008
       No. of Facilities: 262 (estimated)
       No. of Industries: 5
       No. of Occupations: 5
       No. of Employees: 2705 (estimated)
       No. of Female Employees: 159 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Methane, tribromo- 75-25-2
Methanetricarbonitrile, sodium salt 75-25-2
Methane, trichlorofluoro- 75-69-4
Methane, trichloronitro- 76-06-2
Methane, trichloronitroso- 3711-49-7
Methane, chlorodifluoro- 75-45-6
Methane, trifluoro- 75-46-7
Methane, trifluoroiodo- 2314-97-8
Methane, triiodo- 75-47-8
Methane, trinitro- 517-25-9
Methane, tris(4-aminophenyl)- 548-61-8
Methane, tris(propoxymethyl)nitro- 63869-37-4
Methanimidamide,N'-(8-(((aminocarbonyl)oxy)methyl)-1,1a,2,4,7,8,8a,8b-octahydro-8a-hydroxy-1,5-dimethyl-4,7-dioxoazirino(2',3':3,4)pyrrolo(1,2-a)indol-6-yl)-N,N-dime thyl-,(1aS-(1a-alpha,8-alpha,8a-alpha,8b-alpha))- 105551-80-2
Methanimidamide, N,N'-bis(1,3-benzodioxol-5-yl)- 75859-60-8
Methanimidamide,N,N-bis(2-hydroxyethyl)-N'-(5-((2,6-dichlorophenyl)methyl)- 1,2,4-oxadiazol-3-yl)-, hydrochloride 70925-94-9
Methanimidamide, N,N'-bis(2-methoxyphenyl)- 68012-05-5
Methane, chlorodinitro- 921-13-1
Methanimidamide, N,N'-bis(5-methyl-3-isoxazolyl)- 75859-61-9
Methanimidamide, N,N'-bis(1-methyl-2-phenylethyl)- 61945-58-2
Methanimidamide,N,N'-bis(1-methyl-2-phenylethyl)-N-methyl- 61945-55-9
Methanimidamide, N,N'-bis(4-(1-oxopropoxy)phenyl)- 75867-01-5
Methanimidamide, N,N'-bis(2-phenylethyl)-, hydrate 2303-90-4
Methanimidamide, N,N'-bis(3-(trifluoromethyl)phenyl)- 16659-14-6
Methanimidamide,N'-(5-((2-chloro-6-fluorophenyl)methyl)-1,2,4-oxadiazol-3-yl)-N,N-dimethyl- 70926-10-2
Methanimidamide,N'-(5-chloro-4-formyl-1-phenyl-1H-pyrazol-3-yl)-N,N-dimethyl- 62208-78-0
Methanimidamide, N'-cyano-N,N-dimethyl- 39687-97-3
Methanimidamide,N'-(2-cyano-4-oxo-3(4H)-quinazolinyl)-N,N-dimethyl- 64843-08-9
Methane, chlorodinitroiodo- 40956-65-8
Methanimidamide,N'-(5-((2,6-dichlorophenyl)methyl)-1,2,4-oxadiazol-3-yl)-N,N-dimethyl-, hydrochloride 70926-03-3
Methanimidamide,N'-(1,6-dihydro-6-oxo-2-pyridinyl)-N,N-dipropyl- 111757-17-6
Methanimidamide,N'-(2-(3,4-dimethoxyphenyl)ethyl)-N,N-dimethyl-,phosphate (1:1) 61945-50-4
Methanimidamide,N,N-dimethyl-N'-(5,5-dimethyl-3-oxo-1-cyclohexen-1-yl)- 131929-02-7
Methanimidamide,N,N-dimethyl-N'-(1-methyl-2-phenylethyl)-, phosphate(1:1) 61945-48-0
Methanimidamide,N,N-dimethyl-N'-(3-oxo-5-phenyl-1-cyclohexen-1-yl)- 131929-03-8
Methanimidamide,N,N-dimethyl-N'-(2-(2-oxo-1-pyrrolidinyl)ethyl)-,dihydrochloride 92884-75-8
Methanimidamide, N,N-dimethyl-N'-(2-phenylethyl)-,phosphate (1:1) 92884-75-8
Methanimidic acid,N-((2-(cyanoimino)-1-pyrrolidinyl)acetyl)-2-(2,4-dinitrophenyl)hydrazide 159383-33-2
Methanimidic acid, N-((2-oxo-1-pyrrolidinyl)acetyl)-,2-(4-nitrophenyl)hydrazide 95356-56-2
Methane, chlorofluoro- 593-70-4
4a,8a-(Methaniminomethano)naphthalene,10-(cyclopropylmethyl)-1,4,5,8-tetrahydro-,hydrochloride 17713-06-3
4a,8a-(Methaniminomethano)naphthalene,1,2,3,4,5,8-hexahydro-, hydrochloride 17730-84-6
4a,8a-(Methaniminomethano)naphthalene,1,2,3,4,5,8-hexahydro-10-methyl-, hydrochloride 17713-05-2
4a,8a-(Methaniminomethano)naphthalene,1,4,5,8-tetrahydro-, hydrochloride 17730-83-5
4a,8a-(Methaniminomethano)naphthalene,1,4,5,8-tetrahydro-10-methyl-, hydrochloride 17730-63-1
4a,8a-(Methaniminomethano)naphthalen-2-ol,1,2-alpha,3,4,5,6,7,8-octahydro-10-methyl-, benzoate(ester), hydrochloride 17713-07-4
4a,8a-(Methaniminomethano)naphthalen-2-ol,1,2-beta,3,4,5,6,7,8-octahydro-10-methyl-, benzoate(ester), hydrochloride 17747-52-3
9,10-Methanoanthracene,9,10-dihydro-9-gamma-methylaminopropyl-,hydrochloride 60070-44-2
2H-3,7-Methanoazacycloundecino(5,4-b)indole-9-carboxylic acid, 9-((2-beta,3-beta,4-beta,5-alpha,12-beta,19-alpha)-4-(acetyloxy)-3'-(2-chloroethyl)-6,7-didehydro-1 6-methoxy-1-methyl-2',4'-dioxospiro(aspidospermidine-3,5'-oxazolidin)-15-yl)-5-ethyl-1,4,5,6, 7,8,9,10- octahydro-5-hydroxy-,methyl ester, (3R-(3R*,5S*,7R*,9S*))- 67699-40-5
2H-3,7-Methanoazacycloundecino(5,4-b)indole-9-carboxylic acid, 9-((2-beta,3-beta,4-beta,5-alpha,12-beta,19-alpha)-4-(acetyloxy)-3'-(2-chloroethyl)-6,7-didehydro-16- methoxy-1-methyl-2',4'-dioxospiro(aspidospermidine-3,5'-oxazolidin)-15-yl)-5-ethyl-1,4,5,6, 7,8,9,10- octahydro-5-hydroxy-,methyl ester, (3R-(3R*,5S*,7R*,9S*))-,1,5-naphthalenedisulfonate (1:1) (salt) 99759-07-6
Methane, chlorotrifluoro- 75-72-9

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com