Alkyl aryl sulfonate
SUBSTANCE DEFINITION :
A synthetic anionic detergent, containing a minimum of 40% sodium alkyl aryl
sulfonate, 2% moisture, 1% unsulfonated oil and the balance sodium sulfate
REFERENCE :
JPHAA3 Journal of the American Pharmaceutical Association. (Washington, DC)
V.1-28, 1912-39; New series: V.1-17, 1961-77.
CAS  
:
109042-63-9
SYNONYMS  
:
* Witconate
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AZ8400000
CHEMICAL NAME : Alkyl aryl sulfonate
SUBSTANCE DEFINITION :
A synthetic anionic detergent, containing a minimum of 40% sodium alkyl aryl
sulfonate, 2% moisture, 1% unsulfonated oil and the balance sodium sulfate
REFERENCE :
JPHAA3 Journal of the American Pharmaceutical Association. (Washington, DC)
V.1-28, 1912-39; New series: V.1-17, 1961-77.
LAST UPDATED : 199506
DATA ITEMS CITED : 5
SYNONYMS/TRADE NAMES :
* Witconate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2320 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 42,489,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2010 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 42,489,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1730 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 42,489,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE/DURATION : 1131 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 42,489,1953
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1800 mg/kg/30D-I
TOXIC EFFECTS :
Liver - fatty liver degeneration
Kidney, Ureter, Bladder - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - multiple enzyme effects
REFERENCE :
JTOTDO Journal of Toxicology, Cutaneous and Ocular Toxicology. (Marcel
Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1982-
Volume(issue)/page/year: 11,3,1992
*** END OF RECORD ***
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