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MSDS  : Ammonium, alkyldimethylbenzyl-, chloride
CAS  : 8001-54-5
SYNONYMS  : * Alkyl dimethylbenzyl ammonium chloride * Alkyldimethyl(phenylmethyl)quaternary ammonium chlorides * Ammonyx * Arquad dmmcb-75 * Barquat MB-50 * Bayclean * Benirol * Benzalkonium A * Benzalkonium chloride * Bionol * Bio-quat 50-24 * Bio-quat 50-25 * Bio-quat 50-30 * Bio-quat 50-40 * Bio-quat 50-42 * Bio-quat 50-60 * Bio-quat 50-65 * Bio-quat 80-24 * Bio-quat 80-28 * Bio-quat 80-40 * Bio-quat 80-42 * BTC * BTC 50 * BTC 65 * BTC 100 * BTC 824 * BTC 2565 * BTC 8248 * BTC 8249 * BTC E-8358 * BTC 50 USP * BTC 65 USP * Cequartyl * Culversan LC 80 * Dimanin A * Dodigen 226 * Drapolene * Drapolex * Enuclen * Gardiquat 1450 * Gardiquart SV480 * Genamin KDS * Germicin * Germitol * Intexan LB-50 * Kemamine BAC * Marinol * Mefarol * Neo Germ-I-tol * Onyx BTC (Onyx oil & chem Co) * Osvan * Paralkan * Pheneene germicidal solution and tincture * Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides * Quaternium-1 * Romergal CB * Triton K-60 * Vikrol RQ * Zephiral * Zephiran chloride
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : BO3150000
CHEMICAL NAME : Ammonium, alkyldimethylbenzyl-, chloride
CAS REGISTRY NUMBER : 8001-54-5
OTHER CAS REGISTRY NOS. : 8011-91-4
8039-63-2
12741-06-9
8036-90-6
8045-21-4
59890-14-1
75635-12-0
39434-18-9
LAST UPDATED : 199801
DATA ITEMS CITED : 25
WISWESSER LINE NOTATION : AK1&1&1R &G
COMPOUND DESCRIPTOR : Agricultural Chemical
Drug
Mutagen
Reproductive Effector
Human
Primary Irritant
SYNONYMS/TRADE NAMES :
* Alkyl dimethylbenzyl ammonium chloride
* Alkyldimethyl(phenylmethyl)quaternary ammonium chlorides
* Ammonyx
* Arquad dmmcb-75
* Barquat MB-50
* Bayclean
* Benirol
* Benzalkonium A
* Benzalkonium chloride
* Bionol
* Bio-quat 50-24
* Bio-quat 50-25
* Bio-quat 50-30
* Bio-quat 50-40
* Bio-quat 50-42
* Bio-quat 50-60
* Bio-quat 50-65
* Bio-quat 80-24
* Bio-quat 80-28
* Bio-quat 80-40
* Bio-quat 80-42
* BTC
* BTC 50
* BTC 65
* BTC 100
* BTC 824
* BTC 2565
* BTC 8248
* BTC 8249
* BTC E-8358
* BTC 50 USP
* BTC 65 USP
* Cequartyl
* Culversan LC 80
* Dimanin A
* Dodigen 226
* Drapolene
* Drapolex
* Enuclen
* Gardiquat 1450
* Gardiquart SV480
* Genamin KDS
* Germicin
* Germitol
* Intexan LB-50
* Kemamine BAC
* Marinol
* Mefarol
* Neo Germ-I-tol
* Onyx BTC (Onyx oil & chem Co)
* Osvan
* Paralkan
* Pheneene germicidal solution and tincture
* Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
* Quaternium-1
* Romergal CB
* Triton K-60
* Vikrol RQ
* Zephiral
* Zephiran chloride

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 150 ug/3D (Intermittent)
REACTION SEVERITY : Mild
REFERENCE :
85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill,
V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
Volume(issue)/page/year: -,127,1977

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Human
DOSE/DURATION : 50 ug
REACTION SEVERITY : Severe
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N.
Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918-
Volume(issue)/page/year: 27,1118,1944

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 2 mg/24H
REACTION SEVERITY : Severe
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
6,701,1964

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
33NFA8 "Animal Models in Dermatology: Relevance to Human Dermatopharmacology
and Dermatotoxicology," Maibach, H., ed., New York, Churchill Livingston,
1975 Volume(issue)/page/year: -,2,1975

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 ug
REFERENCE :
AROPAW Archives of Ophthalmology (Chicago). (AMA, 535 N. Dearborn St.,
Chicago, IL 60610) New series: V.1-44(3), 1929-50; V.64- 1960-
Volume(issue)/page/year: 34,99,1945

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1 mg/24H
REACTION SEVERITY : Severe
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
6,701,1964

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 10 mg
REACTION SEVERITY : Mild
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
55,501,1980

** ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 266 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
Gastrointestinal - changes in structure or function of esophagus
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke,
Hants., RG 21 2XS, UK) V.1- 1981- Volume(issue)/page/year: 7,191,1988

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 240 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - nausea or vomiting
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,219,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 14500 ug/kg
TOXIC EFFECTS :
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
Gastrointestinal - ulceration or bleeding from small intestine
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,219,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,219,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 13900 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,219,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 64 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,219,1970

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 274 gm/kg/2Y-C
TOXIC EFFECTS :
Behavioral - food intake (animal)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,263,1951

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 13125 mg/kg/15W-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,263,1951

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravaginal
SPECIES OBSERVED : Rodent - rat
DOSE : 50 mg/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins
Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year: 5,398,1985

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravaginal
SPECIES OBSERVED : Rodent - rat
DOSE : 100 mg/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins
Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year: 5,398,1985

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravaginal
SPECIES OBSERVED : Rodent - rat
DOSE : 200 mg/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins
Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year: 5,398,1985

** MUTATION DATA **

TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 50 ug/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 193,21,1988

TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Rodent - hamster Embryo
DOSE/DURATION : 1 mg/L
REFERENCE :
SHIGAZ Shigaku. Ondotology. (Nippon Shika Daigaku Shigakkai, 1-9-20
Fujimi, Chiyodaku, Tokyo 102, Japan) V.38- 1949-
Volume(issue)/page/year: 74,1365,1987

*** REVIEWS ***

TOXICOLOGY REVIEW
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year:
32,245,1974

TOXICOLOGY REVIEW
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 8(4),589,1989

*** U.S. STANDARDS AND REGULATIONS ***

EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - T1554
No. of Facilities: 1244 (estimated)
No. of Industries: 23
No. of Occupations: 13
No. of Employees: 52380 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - T1554
No. of Facilities: 18923 (estimated)
No. of Industries: 125
No. of Occupations: 80
No. of Employees: 486761 (estimated)
No. of Female Employees: 309834 (estimated)


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Ammonium, alkyldimethylbenzyl-, chloride 8001-54-5
Ammonium, alkyl(C14-16)dimethylbenzyl-, chlorides 63449-41-2
Ammonium, alkyl(C8-C18)dimethyl 3,4-dichlorobenzyl-,chloride 8023-53-8
Ammonium, N-alkyl(C9-15)tolyl methyltrimethyl-,chloride 1399-80-0
Ammonium,(2-(5-allyl-1-benzyl-5-isopropyl-2,4,6(1H,3H,5H)trioxo-3-pyrimidinyl)ethyl) diethylmethyl-, iodide 77967-02-3
Ammonium,(3-(allylcarbamoyl)-3,3-diphenyl-1-methylpropyl)trimethyl-, bromide 77967-02-3
Ammonium, allyl(2-carboxyethyl)dimethyl-, bromide,ester with allyl(2-hydroxyethyl)dimethyl ammoniumbromide 77967-02-3
Alcohols, C9-11 66455-17-2
Ammonium,allyl(3-(2-chloro-phenothiazin-10-yl)propyl)dimethyl-, chloride 66455-17-2
Ammonium,allyldiethyl(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)-, bromide 35690-06-3
Ammonium, allyldiethyl(2-hydroxyethyl)-, bromide,1-hydroxy-alpha-phenylcyclohexaneacetate 35690-06-3
Ammonium,allyldiethyl(((2,4,6-trimethylphenyl)carbamoyl)methyl)- 84213-91-2
Ammonium, allyldiethyl((2,6-xylylcarbamoyl)methyl)-,chloride 5369-06-2
Ammonium,allyldimethyl(2-(3-acetyl-2-methyl-1-indolizinyl)-2-methylethyl)-, bromide 66902-67-8
Ammonium,allyldimethyl(2-hydroxy-3-(1-naphthyloxy)propyl)-,bromide 87436-38-2
Ammonium,allyldimethyl(2-(4-oxo-3(4H)-quinazolinyl)ethyl)-,bromide 87436-38-2
Ammonium, allyldimethylphenyl-, iodide 73680-59-8
Ammonium,(2-(2-allyl-6-methoxyphenoxy)ethyl)diallylmethyl-,iodide 73680-59-8
Alcohols, C10-16 67762-41-8
Ammonium,(2-(4-allyl-2-methoxyphenoxy)ethyl)trimethyl-, iodide 67762-41-8
Ammonium,(2-(4-(2-allyloxybenzamido)benzoyloxy)ethyl)diethylmethyl-, bromide 51444-55-4
Ammonium, (allyloxymethyl)triethyl-, iodide 51444-55-4
Ammonium, (allyloxymethyl)trimethyl-, iodide 51444-55-4
Ammonium, allyltriethyl-, iodide 4186-64-5
Ammonium, allyltrimethyl-, chloride 1516-27-4
Ammonium, allyltrimethyl-, iodide 13448-30-1
Ammonium, (2-(amidinothio)ethyl)trimethyl-, bromide,monohydrobromide 18129-31-2
Ammonium, (3-(amidinothio)propyl)triethyl-, bromide,hydrobromide 18129-31-2
Ammonium, (3-(amidinothio)propyl)trimethyl-, bromide,hydrobromide 18129-31-2
Alcohols, C12-15, ethoxylated propoxylated 68551-13-3
Ammonium, (2-(o-aminobenzamido)ethyl)diethylmethyl-,bromide 1910-56-1
Ammonium, (2-(p-aminobenzamido)ethyl)diethylmethyl-,bromide 97340-06-2
Ammonium, 3-(p-aminobenzoyloxy)phenyltrimethyl-,bromide 64048-57-3
Ammonium, (4-amino-2-hydroxybutyl)trimethyl-,chloride, hydrochloride 64048-57-3
Ammonium, (2-((aminoiminomethyl)thio)ethyl)triethyl-,bromide, monohydrobromide 34521-14-7
Ammonium,(3-(p-amino-N-(p-methoxybenzyl)benzamido)propyl)diethylmethyl-, bromide 103072-07-7
Ammonium,(3-(p-amino-N-(alpha-methylbenzyl)benzamido)propyl)diethylmethyl-, bromide 103072-08-8
Ammonium,(2-(p-amino-N-phenylbenzamido)ethyl)diethylmethyl-,bromide 100773-63-5
Ammonium, (m-aminophenyl)trimethyl-, iodide 64048-58-4
Ammonium, (p-aminophenyl)trimethyl-, iodide 18953-50-9
Alcohol sulphate 61711-25-9
Ammonium, androsta-3,5-dien-17-beta-yltrimethyl-,iodide 26041-59-8
Ammonium,(5-alpha-androstan-3-alpha,17-alpha-ylene)bis(diethylmethyl-, diiodide 66-50-2
Ammonium,(5-alpha-androstan-3-alpha,17-alpha-ylene)bis(dimethylethyl-, diiodide 72-60-6
Ammonium,(5-alpha-androstan-3-beta,17-beta-ylene)bis(dimethyl(2-hydroxyethyl)-, dibromide, diacetate 50588-19-7
Ammonium,(5-alpha-androstan-3-alpha,17-alpha-ylene)bis(triethyl-, diiodide 66-36-4
Ammonium,(5-alpha-androstan-3-alpha,17-alpha-ylene)bis(trimethyl-, diiodide 66-64-8
Ammonium,(5-anilino-9H-benzo(a)phenoxazin-9-ylidene)diethyl-,nitrate 20816-95-9
Ammonium,((N-anthraquinon-2-yl)aminomethylene)dimethyl-,chloride 62399-48-8
Ammonium antimony sodium tungsten oxide 89899-81-0

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