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MSDS  : Oxamic acid, (2-amino-2-carboxyethyl)-, L-
CAS  : 5302-45-4
SYNONYMS  : * L-Alanine, 3-((carboxycarbonyl)amino)- * BOAA * 3-((Carboxycarbonyl)amino)-L-alanine * Dencichin * Dencichine * L-Dencichin * Neurotoxin (Lathyrus sativus) * L-3-Oxalylamino-2-aminopropionic acid * Ox-Dapro
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : RO4555000
CHEMICAL NAME : Oxamic acid, (2-amino-2-carboxyethyl)-, L-
CAS REGISTRY NUMBER : 5302-45-4
BEILSTEIN REFERENCE NO. : 2259036
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C5-H8-N2-O5
MOLECULAR WEIGHT : 176.15
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* L-Alanine, 3-((carboxycarbonyl)amino)-
* BOAA
* 3-((Carboxycarbonyl)amino)-L-alanine
* Dencichin
* Dencichine
* L-Dencichin
* Neurotoxin (Lathyrus sativus)
* L-3-Oxalylamino-2-aminopropionic acid
* Ox-Dapro

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 301 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
48,1,1979

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 2006 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
47,135,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 1043 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China
International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
1980- Volume(issue)/page/year: 17,274,1986

*** END OF RECORD ***
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