Search   
MSDS  
:
 2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-
CAS  
:
 1665-48-1
SYNONYMS  
:
 * AHR-438
* CL 39,148
* 5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone
* Metaxalone
* Metazalone
* Metazolone
* Skelaxin
* Zorane
* 5-((3,5-Xylyloxy)methyl)-2-oxazolidinone

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ3850000
CHEMICAL NAME           : 2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-
CAS REGISTRY NUMBER     : 1665-48-1
BEILSTEIN REFERENCE NO. : 0884592
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H15-N-O3
MOLECULAR WEIGHT        : 221.28
WISWESSER LINE NOTATION : T5MVOTJ D1OR C1 E1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AHR-438
   * CL 39,148
   * 5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone
   * Metaxalone
   * Metazalone
   * Metazolone
   * Skelaxin
   * Zorane
   * 5-((3,5-Xylyloxy)methyl)-2-oxazolidinone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 775 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,261,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 515 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,242,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1690 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - rigidity (including catalepsy)
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 233,326,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 490 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,261,1972
 
                            *** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
2-Oxazolidinone,5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)- 139-91-3
2-Oxazolidinone,5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-, monohydrochloride 3759-92-0
2-Oxazolidinone,5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-, L-, monohydrochloride 3031-51-4
2-Oxazolidinone,5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-, methiodide 3031-51-4
2-Oxazolidinone,5-(morpholinomethyl)-3-(((5-nitro-2-furoyl)methylene)amino)- 92297-09-1
2-Oxazolidinone,5-(morpholinomethyl)-3-(((5-nitro-2-furoyl)methylene)amino)-, hydrochloride 97158-93-5
Oxayohimban-16-carboxylic acid,16,17-didehydro-10,11-dimethoxy-19-methyl-, methylester, (3-beta,19-alpha,20-alpha)- 131-02-2
2-Oxazolidinone,5-(morpholinomethyl)-3-(((5-nitro-2-furoyl)methylene)amino)-, methiodide 97619-17-5
2-Oxazolidinone,5-(morpholinomethyl)-3-((3-(5-nitro-2-furyl)allylidene)amino)- 3318-79-4
2-Oxazolidinone,5-(morpholinomethyl)-3-((5-nitro-1-methyl-2-imidazolyl)methyleneamino)-, hydrochloride 30185-92-3
2-Oxazolidinone, 5-(morpholinomethyl)-3-phenyl-,monohydrochloride 27125-00-4
2-Oxazolidinone, 3-((5-nitrofurfurylidene)amino)- 67-45-8
2-Oxazolidinone,3-((5-nitro-2-furfurylidene)amino)-5-((4-octyl-1-piperazinyl)methyl)-, dihydrochloride 96059-01-7
2-Oxazolidinone,3-((5-nitro-2-furfurylidene)amino)-5-((4-propyl-1-piperazinyl)methyl)- 94374-28-4
2-Oxazolidinone,3-(((5-nitro-2-furoyl)methylene)amino)- 90323-37-8
2-Oxazolidinone,3-((3-(5-nitro-2-furyl)allylidene)amino)- 3318-78-3
2-Oxazolidinone,3-(p-nitrophenyl)-5-(2-propynyloxymethyl)- 23598-64-3
Oxayohimban-16-carboxylic acid,16,17-didehydro-1,19-dimethyl-, hydrazide,(19-alpha)- 72442-35-4
2-Oxazolidinone, 5-((2-phenoxyphenyl)methyl)- 62826-06-6
2-Oxazolidinone, 5-phenyl- 7693-77-8
2-Oxazolidinone, 5-(phenylmethyl)- 42746-49-6
2-Oxazolidinone, 3-phenyl-5-(piperidinomethyl)-,monohydrochloride 27125-08-2
2-Oxazolidinone, 3-phenyl-5-(2-propynyloxymethyl)- 23598-54-1
2-Oxazolidinone, 5-(1-piperidinylmethyl)-3-propyl-,monohydrobromide 52467-73-9
2-Oxazolidinone, 5-((2-(2-propenyloxy)phenyl)methyl)- 62826-13-5
2-Oxazolidinone, 3-propyl-5-(2-propynyloxymethyl)- 23598-89-2
2-Oxazolidinone, 5-phenyl-3-(1-pyrrolidinylcarbonyl)- 55243-73-7
2-Oxazolidinone, 5-(2-propynyloxymethyl)-3-(m-tolyl)- 23598-51-8
Oxayohimban-16-carboxylic acid,16,17-didehydro-1,19-dimethyl-, hydrazide,(19-alpha,20- alpha)- 72407-42-2
2-Oxazolidinone, 5-(2-propynyloxymethyl)-3-(o-tolyl)- 23598-52-9
2-Oxazolidinone, 5-(2-propynyloxymethyl)-3-(p-tolyl)- 23598-50-7
2-Oxazolidinone,5-(2-propynyloxymethyl)-3-(alpha,alpha,alpha-trifluoro-m-tolyl)- 23598-53-0
2-Oxazolidinone,5-(2-propynyloxymethyl)-3-(alpha,alpha,alpha-trifluoro-o-tolyl)- 23598-61-0
2-Oxazolidinone,5-(2-propynyloxymethyl)-3-(alpha,alpha,alpha-trifluoro-p-tolyl)- 23598-48-3
2-Oxazolidinone,5-((2-(trifluoromethyl)phenyl)methyl)- 62826-05-5
2-Oxazolidinone,5-((3-(trifluoromethyl)phenyl)methyl)- 62826-04-4
2-Oxazolidinone, 3-(3,4,5-trimethoxybenzoyl)- 50915-99-6
2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)- 1665-48-1
2-Oxazolidone, 3-((2-furanylmethylene)amino)- 6270-33-3
Oxayohimban-16-carboxylic acid,16,17-didehydro-10-methoxy-19-methyl-, hydrazide,(19-alpha)- 72407-38-6
2-Oxazolidone,3-(furfurylideneamino)-4-(piperidinomethyl)- 126268-12-0
2-Oxazolidone, 3-(3-furyl-2-propenylideneamino)- 126268-04-0
2-Oxazolidone,3-((1-methylpyrrol-2-yl)methyleneamino)- 126268-08-4
2-Oxazolidone,3-((1-methylpyrrol-2-yl)methyleneamino)-4-(piperidinomethyl)- 126268-14-2
2-Oxazolidone, 3-((m-nitrophenyl)methyleneamino)- 35407-07-9
2-Oxazolidone, 3-((o-nitrophenyl)methyleneamino)- 19687-73-1
2-Oxazolidone, 3-((p-nitrophenyl)methyleneamino)- 90946-87-5
2-Oxazolidone, 3-(phenylmethyleneamino)- 4341-14-4
2-Oxazolidone, 3-(pyrrol-2-ylmethyleneamino)- 126268-10-8
2-Oxazolidone,3-(pyrrol-2-ylmethyleneamino)-4-(piperidinomethyl)- 126268-13-1

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