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MSDS  : Phenethylamine, alpha-methyl-3,4,5-trimethoxy-, hydrochloride
CAS  : 5688-80-2
SYNONYMS  : * Amphetamine, 3,4,5-trimethoxy-, hydrochloride * Benzeneethanamine, 3,4,5-trimethoxy-alpha-methyl-, hydrochloride * alpha-Methyl-3,4,5-trimethoxyphenethylamine hydrochloride * Phenethylamine, 3,4,5-trimethoxy-alpha-methyl-, hydrochloride * 3,4,5-Trimethoxyamphetamine hydrochloride * 3,4,5-Trimethoxy-alpha-methyl-beta-phenylethylamine hydrochloride * 1-(3,4,5-Trimethoxyphenyl)-2-aminopropane
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : SI2285000
CHEMICAL NAME : Phenethylamine, alpha-methyl-3,4,5-trimethoxy-,
hydrochloride
CAS REGISTRY NUMBER : 5688-80-2
LAST UPDATED : 198910
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C12-H19-N-O3.Cl-H
MOLECULAR WEIGHT : 261.78
WISWESSER LINE NOTATION : Z1Y1&R CO1 DO1 EO1 &GH
COMPOUND DESCRIPTOR : Drug
Human
SYNONYMS/TRADE NAMES :
* Amphetamine, 3,4,5-trimethoxy-, hydrochloride
* Benzeneethanamine, 3,4,5-trimethoxy-alpha-methyl-, hydrochloride
* alpha-Methyl-3,4,5-trimethoxyphenethylamine hydrochloride
* Phenethylamine, 3,4,5-trimethoxy-alpha-methyl-, hydrochloride
* 3,4,5-Trimethoxyamphetamine hydrochloride
* 3,4,5-Trimethoxy-alpha-methyl-beta-phenylethylamine hydrochloride
* 1-(3,4,5-Trimethoxyphenyl)-2-aminopropane

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - man
DOSE/DURATION : 880 ug/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
Behavioral - changes in motor activity (specific assay)
Gastrointestinal - nausea or vomiting
REFERENCE :
JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For
publisher information, see BJPYAJ. Volume(issue)/page/year: 101,317,1955

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 149 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
25,299,1973

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
25,299,1973

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 23 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
Gastrointestinal - nausea or vomiting
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
25,299,1973

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 31 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
Gastrointestinal - nausea or vomiting
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
25,299,1973

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 172 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
25,299,1973

*** END OF RECORD ***
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