* 3-Amino-7-(dimethylamino)phenothiazin-5-ium chloride
* Azure A
* Azur A
* C.I. 52005
* asym-Dimethyl-3,7-diaminophenazathionium chloride
* Dimethylthionine
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SP5660000
CHEMICAL NAME : Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-,
chloride
CAS REGISTRY NUMBER : 531-53-3
OTHER CAS REGISTRY NOS. : 959-03-5
8000-86-0
LAST UPDATED : 199709
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C14-H14-N3-S.Cl
MOLECULAR WEIGHT : 291.82
WISWESSER LINE NOTATION : T C666 BN ISJ FZ MN1&1 &G &12/25
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* 3-Amino-7-(dimethylamino)phenothiazin-5-ium chloride
* Azure A
* Azur A
* C.I. 52005
* asym-Dimethyl-3,7-diaminophenazathionium chloride
* Dimethylthionine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 37720 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SMBUA9 Stanford Medical Bulletin. (Palo Alto, CA) V.1-20, 1942-62.
Discontinued. Volume(issue)/page/year: 9,96,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 59040 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SMBUA9 Stanford Medical Bulletin. (Palo Alto, CA) V.1-20, 1942-62.
Discontinued. Volume(issue)/page/year: 9,96,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 19340 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SMBUA9 Stanford Medical Bulletin. (Palo Alto, CA) V.1-20, 1942-62.
Discontinued. Volume(issue)/page/year: 9,96,1951
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 20 umol/L/5H (Continuous)
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M3031
No. of Facilities: 451 (estimated)
No. of Industries: 4
No. of Occupations: 3
No. of Employees: 2020 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M3031
No. of Facilities: 661 (estimated)
No. of Industries: 2
No. of Occupations: 5
No. of Employees: 5132 (estimated)
No. of Female Employees: 2765 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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