MSDS   | : | p-Phenylenediamine, 2,6-dichloro-
| CAS   | : | 609-20-1 | SYNONYMS   | : | * 1,4-Benzenediamine, 2,6-dichloro-
* C.I. 37020
* Daito Brown Salt RR
* 1,4-Diamino-2,6-dichlorobenzene
* 2,5-Diamino-1,3-dichlorobenzene
* 2,6-Dichloro-1,4-benzenediamine
* 2,6-Dichloro-p-phenylenediamine
* 2,6-Dichloro-1,4-phenylenediamine
* Fast Brown RR Salt
* NCI-C50260
|
| |
|
|
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SS9175000
CHEMICAL NAME : p-Phenylenediamine, 2,6-dichloro-
CAS REGISTRY NUMBER : 609-20-1
BEILSTEIN REFERENCE NO. : 2209257
REFERENCE : 4-13-00-00225 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 15
MOLECULAR FORMULA : C6-H6-Cl2-N2
MOLECULAR WEIGHT : 177.04
WISWESSER LINE NOTATION : ZR DZ BG FG
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* 1,4-Benzenediamine, 2,6-dichloro-
* C.I. 37020
* Daito Brown Salt RR
* 1,4-Diamino-2,6-dichlorobenzene
* 2,5-Diamino-1,3-dichlorobenzene
* 2,6-Dichloro-1,4-benzenediamine
* 2,6-Dichloro-p-phenylenediamine
* 2,6-Dichloro-1,4-phenylenediamine
* Fast Brown RR Salt
* NCI-C50260
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 700 mg/kg
TOXIC EFFECTS :
Liver - other changes
Blood - changes in spleen
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-219,1982
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 87 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-219,1982
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 260 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-219,1982
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 mg/pLate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl
7),1,1986
TYPE OF TEST : Cytogenetic analysis
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 100 mg/kg
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.
11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:
25,302,1995
TYPE OF TEST : Mutation in mammalian somatic cells
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 25 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.
11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:
12,85,1988
TYPE OF TEST : Morphological transformation
TEST SYSTEM : Rodent - hamster Embryo
DOSE/DURATION : 600 umol/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 8,515,1986
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 250 mg/L
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
236,933,1987
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 16 mg/L
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
236,933,1987
*** REVIEWS ***
IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 39,325,1986
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 39,325,1986
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
NTP Carcinogenesis Bioassay (feed);clear evidence:mouse
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-219,82
NTP Carcinogenesis Bioassay (feed);no evidence:rat
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-219,82
*** END OF RECORD ***
|
|
|
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Phenol, pentachloro-, acetate
| 1441-02-7 |
DL-Phenylalanine, N-(1H-indol-3-yloxoacetyl)-, ethylester
| 97529-42-5 |
DL-Phenylalanine, 2-methoxy-5-nitro-, ethyl ester,monohydrochloride
| 116366-15-5 |
L-Phenylalanine,N-(1-(2-methyl-1-oxo-3-((1-oxopropyl)thio)propyl)-L-prolyl)-, (S)-
| 74259-02-2 |
L-Phenylalanine,N-((4-(((2-methylpropoxy)carbonyl)amino)phenyl)sulfonyl)-, ethyl ester
| 81865-24-9 |
D-Phenylalanine, N-(3-(4-nitrophenyl)-3-oxopropyl)-
| 85975-29-7 |
D-Phenylalanine, N-(3-(4-nitrophenyl)-3-oxopropyl)-,monohydrochloride
| 85975-17-3 |
DL-Phenylalanine, N-((5-nitro-2-thienyl)carbonyl)-,(3-(5-nitro-2-furanyl)-2-propenylidene) hydrazide
| 39978-55-7 |
L-Phenylalanine,2-(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazide
| 84409-81-4 |
DL-Phenylalanine, N-(1-oxo-3-phenyl-2-propenyl)-,methyl ester, (E)-
| 127750-60-1 |
DL-Phenylalanine, N-(3-oxo-3-phenylpropyl)-
| 85995-02-4 |
Phenol, pentachloro-, mixt. with chlorinated paraffinoils and 1-chloronaphthalene
| 70645-04-4 |
DL-Phenylalanine, N-(3-oxo-3-phenylpropyl)-,hydrochloride
| 85975-14-0 |
DL-Phenylalanine,N-(3-oxo-3-(4-propoxyphenyl)propyl)-
| 85975-28-6 |
DL-Phenylalanine,N-(3-oxo-3-(4-propoxyphenyl)propyl)-, hydrochloride
| 85975-15-1 |
Phenylalanine, alpha-phenyl-
| 56594-95-7 |
L-Phenylalanine, N-((phenylmethoxy)carbonyl)-,ethenyl ester
| 64187-42-4 |
Phenylalanine, 2-(phosphonomethyl)-, hydrate
| 110762-24-8 |
L-Phenylalanine, 4-(1-piperidinyl)-, beta-
| 71825-29-1 |
L-Phenylalanine,L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucy- L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leu cyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lys yl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt), hydrate
| 99294-94-7 |
Phenyl disulfide
| 882-33-7 |
m-Phenylenediamine
| 108-45-2 |
Phenol, pentachloro-, p-chlorobenzoate
| 2948-12-1 |
o-Phenylenediamine
| 95-54-5 |
p-Phenylenediamine
| 106-50-3 |
o-Phenylenediamine, 4-(p-aminophenoxy)-
| 6264-66-0 |
o-Phenylenediamine, 4-arsenoso-, hydrochloride,hydrate (1:1:3)
| 6264-66-0 |
p-Phenylenediamine, N,N-bis(2-chloroethyl)-
| 2067-58-5 |
p-Phenylenediamine, N,N-bis(2-chloroethyl)-,hydrochloride
| 36134-83-5 |
p-Phenylenediamine, N,N'-bis(1,4-dimethylpentyl)-
| 3081-14-9 |
p-Phenylenediamine, N,N'-bis(1-ethyl-3-methylpentyl)-
| 139-60-6 |
p-Phenylenediamine, N,N-bis(2-hydroxyethyl)-, sulfate(1:1)
| 63886-75-9 |
m-Phenylenediamine, 4-butoxy-, dihydrochloride
| 76486-09-4 |
Phenol, m-(pentachlorophenoxy)-
| 76486-09-4 |
m-Phenylenediamine, 4-chloro-
| 5131-60-2 |
o-Phenylenediamine, 4-chloro-
| 95-83-0 |
p-Phenylenediamine, 2-chloro-
| 615-66-7 |
o-Phenylenediamine,4-chloro-N-(2-(diethylamino)ethyl)-
| 56756-64-0 |
p-Phenylenediamine, 2-chloro-, dihydrochloride
| 615-46-3 |
p-Phenylenediamine, 2-chloro-, sulfate
| 6219-71-2 |
p-Phenylenediamine, N,N'-di-sec-butyl-
| 101-96-2 |
p-Phenylenediamine, N,N'-dibutyl-N,N'-dinitroso-
| 19433-82-0 |
p-Phenylenediamine, 2,5-dichloro-
| 20103-09-7 |
p-Phenylenediamine, 2,6-dichloro-
| 609-20-1 |
Phenol, 2-(pentachlorophenoxy)-
| 78576-68-8 |
p-Phenylenediamine, N,N'-dicyclohexyl-
| 4175-38-6 |
p-Phenylenediamine, N,N-diethyl-
| 93-05-0 |
p-Phenylenediamine, N,N'-diethyl-
| 3010-30-8 |
o-Phenylenediamine, N-(2-(diethylamino)ethyl)-,dihydrochloride
| 101976-54-9 |
p-Phenylenediamine, N,N-diethyl-N',N'-dimethyl-
| 5775-53-1 |
|
|