RTECS NUMBER : SZ6800000
CHEMICAL NAME : Phosphonic acid,
(4-(4-(bis(2-chloroethyl)amino)phenyl)-1-hydroxybutyl
idene)bis-
CAS REGISTRY NUMBER : 104233-81-0
LAST UPDATED : 199410
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C14-H23-Cl2-N-O7-P2
MOLECULAR WEIGHT : 450.22
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* 4-(4-(Bis(2-chloroethyl)amino)phenyl)-1-hydroxybutane-1,1-bisphosphonic
acid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 146 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag
New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93-
1979- Volume(issue)/page/year: 111,209,1986
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 5 mg/plate
REFERENCE :
JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag
New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93-
1979- Volume(issue)/page/year: 111,209,1986
*** END OF RECORD ***
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