===================== Product Identification =====================
MSDS NAME:DACARBAZINE
NIIN:00F039439
MSDS Number: BWWYY
=== Responsible Party ===
Company:FUJISAWA INC (FORMERLY LYPHOMED INC)
Address:2020 RUBY
City:MELROSE PARK
State:IL
ZIP:60160-5000
Country:US
Info Phone Num:708-450-7569/7500
Emergency Phone Num:708-450-7569/7500
CAGE:GO395
=== Contractor Identification ===
Company:FUJISAWA INC (FORMERLY LYPHOMED INC)
Address:2020 RUBY
City:MELROSE PARK
State:IL
ZIP:60160-5000
Country:US
Phone:708-450-7569/7500
CAGE:GO395
Company:LYPHOMED INC DIV OF FUJISAWA USA INC
Address:2020 RUBY ST
Box:City:MELROSE PARK
State:IL
ZIP:60160-1112
Country:US
Phone:312-345-6170
CAGE:60567
============= Composition/Information on Ingredients =============
Name:DACARBAZINE (ANIMAL CARCINOGEN BY IARC, SUSPECTED
CARCINOGEN BY NTP) *95-1*
CAS:4342-03-4
RTECS #:NI3950000
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL LD50 (RAT): 2147 MG/KG
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:NO
Health Hazards Acute and Chronic:EYES: IRRITATION. SKIN: POISONOUS,
IRRITATION, ALLERGIC REACTION. INHALATION: POISONOUS, RESPIRATORY
TRACT IRRITATION, ALLERGIC REACTION. INGESTION: POISONOUS, ALLERGIC
REACTION. MAY CAUSE POSSIBLE HY PERSENSITIZATION, BONE MARROW
DEPRESSION & CANCER.
Explanation of Carcinogenicity:SEE INGREDIENTS.
Effects of Overexposure:IRRITATION, VOMITING, NAUSEA, GI DISTURBANCES.
======================= First Aid Measures =======================
First Aid:INHALATION: REMOVE TO FRESH AIR. INGESTION: FLUSH MOUTH OUT
W/WATER. SKIN/EYES: FLUSH W/WATER. OBTAIN MEDICAL ATTENTION IN ALL
CASES.
===================== Fire Fighting Measures =====================
Extinguishing Media:DRY CHEMICAL, CO2, FOAM AS APPROPRIATE FOR
SURROUNDING FIRE.
Fire Fighting Procedures:WEAR SELF CONTAINED BREATHING APPARATUS &
PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:DRY POWDER MATERIAL IS ASSUMED TO BE
COMBUSTIBLE.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR RECOMMENDED PERSONAL PROTECTIVE
EQUIPMENT. VACUUM/SWEEP UP. ABSORB LIQUID W/PAPER TOWELS. WIPE
WORKING SURFACES TO DRYNESS, THEN WASH W/SOAP & WATER. PLACE
DRUG-SOLID ABSORBENTS INTO A LEAK-PROOF CONTAINER & LABEL
PROPERLY.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN TIGHTLY CLOSED CONTAINERS IN
A COOL AREA. AVOID ALL FORMS OF UNPROTECTED CONTACT. EXPOSURE TO
LIGHT MAY CAUSE DECOMPOSITION.
Other Precautions:IN MIXING/ADMINISTERING THIS PRODUCT, OBSERVE
DIRECTIVES & PRECAUTIONS ISSUED BY THE NATIONAL STUDY COMMISSION ON
CYTOTOXIC EXPOSURE.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WEAR A NIOSH APPROVED RESPIRATOR.
Ventilation:LOCAL EXHAUST RECOMMENDED.
Protective Gloves:DISPOSABLE SURGICAL LATEX
Eye Protection:SAFETY GOGGLES
Other Protective Equipment:DISPOSABLE PROTECTIVE APPAREL
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE.
Supplemental Safety and Health
================== Physical/Chemical Properties ==================
pH:3-4
Solubility in Water:COMPLETE
Appearance and Odor:WHITE TO IVORY LYOPHILIZED POWDER W/NO ODOR.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:LIGHT.
Hazardous Decomposition Products:TOXIC FUMES WHEN HEATED TO
DECOMPOSITION.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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