===================== Product Identification =====================
MSDS NAME:ZINC OXIDE
NIIN:00N091069
Status Code:A
MSDS Number: CJFZR
=== Responsible Party ===
Company:NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY
Address:100 BUREAU DR
City:GAITHERSBURG
State:MD
ZIP:20899
Country:US
Emergency Phone Num:(800)424-9300
Chemtrec Ind/Phone:(800)424-9300
CAGE:0HV88
=== Contractor Identification ===
Company:NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY
Address:100 BUREAU DR
Box:City:GAITHERSBURG
State:MD
ZIP:20899
Country:US
Phone:301-975-2019;301-975-6439
CAGE:0HV88
============= Composition/Information on Ingredients =============
Name:ZINC OXIDE
CAS:1314-13-2
RTECS #:ZH4810000
= Wt:100.
OSHA PEL:15 MG/M3
ACGIH TLV:10 MG/M3 (DUST)
===================== Hazards Identification =====================
LD50 LC50 Mixture:LD50 (ORAL,RAT) >8437 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: INHAL OF ZINC OXIDE DUST/POWDER
MAY CAUSE IRRIT OF RESP TRACT & CHEM PNEUM. EXPOS TO FRESHLY FORMED
FUMES OF ZINC OXIDE MAY RSLT IN ZINC FUME FEVER. ZINC FUME FEVER IS
INFLUENZA-LIKE ILLNESS TH AT MAY OCCUR TO INHAL OF FRESHLY
FORMEDMETAL OXIDE PARTICLES SIZED <1.5 MICRONS & USUALLY BETWEEN
0.02-0.05 MICRONS. SYMPS MAY BE DELAYED 4-12 HRS & BEGIN W/SUDDEN
ONSET OF THIRST & SWEET, METALLIC/FO UL TASTE IN MOUTH. OTHER SYMPS
MAY INCL UPPER RESP TRACT IRRIT ACCOMPANIED BY COUGH & DRYNESS OF
MUC MEMB, LASSITUDE & GENERALIZED FEELING OF MALAISE. FEVER,
CHILLS, MUSCULAR PAIN, (EFTS OF OVEREXP)
Effects of Overexposure:HLTH HAZ: MILD TO SEV HDCH, NAUS, OCCASIONAL
VOMIT, EXAGGERATED MENTAL ACTIVITY, PROFUSE SWEAT, EXCESS
URINATION, DIARR & PROSTRATION MAY ALSO OCCUR. TOLERANCE TO FUMES
MAY DEVELOP RAPIDLY, BUT IS QUI CKLY LOST. PRELIMINARY EXPOS TO
ACETIC ACID VAPS MAY INCR SUSCEPTIBILITY TO ZINC FUME FEVER. LETHAL
DOSE RPTD IN MICE WAS 2500 MG/M3. RPTD/PRLNGD EXPOS TO ZINC OXIDE
MAY PRDCE LATENT LIVER DYSFUNCTION & GI DISTURB W/PRESS IN STOM
REGION, NAUS, & WEAK. ZINC OXIDE IS CONSTITUENT OF MANY TOPICAL
DERMATOLOGICAL PREPARATIONS AND HAS DEMONSTRATED LOW POTNTL FOR
SKIN IRRIT, ALTHOUGH IT CAN ALTER (SUPDAT)
Medical Cond Aggravated by Exposure:PERSONS WITH A HISTORY OF CHRONIC
RESPIRATORY DISEASE.
======================= First Aid Measures =======================
First Aid:SKIN CONT: REMOVE CONTAMD SHOES & CLTHG. RINSE AFFECTED AREA
W/LG AMTS OF WATER FOLLOWED BY WASHING AREA W/SOAP & WATER. CONT
MED ASSISTANCE IF NEC. EYE CONT: IMMED FLUSH, INCL UNDER EYELIDS,
W/COPIOU S AMTS OF WATER FOR AT LST 15 MINS. CONT MED ASSISTANCE IF
NEC. INHAL: REMOVE TO FRESH AIR. IF BRTHG IS DFCLT, GIVE OXYG; IF
VICTIM IS NOT BRHTG, GIVE ARTF RESP. CONT MED ASSISTANCE IF NEC.
INGEST: WA SH OUT MOUTH W/WATER. CONT MED ASSISTANCE IF NECESSARY.
TARGET ORGAN(S) OF ATTACK: POISONING MAY EFFECT THE RESPIRATORY
TRACT.
===================== Fire Fighting Measures =====================
Extinguishing Media:THIS MATERIAL IS NONCOMBUSTIBLE. USE EXTINGUISHING
MEDIA THAT IS APPROPRIATE TO THE SURROUNDING FIRE.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA & FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:NO UNUSUAL FIRE/EXPLO HAZS ARE ASSOC
W/THIS MATL. HOWEVER, ZINC OXIDE WILL PRESENT IGNIT AND/OR EXPLO
HAZ W/FOLLOWING MATLS: CHLORINATED RUBBER: VIOLENT/EXPLOSIVE RXN
WHEN HEATED >216C. LINSEED OIL: E XOTHERMIC RXN W/POSSIBLE IGNIT.
MAGNESIUM: EXPLOSION RXN ON HEATING.
================== Accidental Release Measures ==================
Spill Release Procedures:NOTIFY SFTY PERSONNEL OF MAJOR SPILLS AND/OR
LEAKS. EVACUATE ALL NONESSENTIAL PERSONNEL. AVOID RAISING DUST.
RECOVER SMALL SPILLS W/CLEAN SHOVEL, AND PLACE INTO A CLEAN, DRY
CONTAINER FOR LATER DISPOS AL. REMAINING RESIDUE SHOULD BE CLEANED
UP USING HIGH EFFICIENCY PARTICULATE FILTER.
====================== Handling and Storage ======================
Handling and Storage Precautions:PERSONS HNDLG MATL WEAR NIOSH APPRVD
AIR-PURIFYING RESP W/HIGH-EFFICIENCY PARTICULATE FILTER. SPECIFIC
RESP SELECTED MUST BE BASED ON CONTAM LEVELS FOUND IN WORKPLACE,
MUST BE BASED ON SPECIFIC OPERAT ION, MUST NOT EXCEED WORKING
LIMITS OF RESP & MUST BE JOINTLY APPRVD BY NIOSH & MSHA.(OTHER
PREC)
Other Precautions:HNDLG & STOR PREC: ADDNL PROT CLTHG SUCH AS GLOVES,
LAB COATS & SPLASH-PROOF/DUST RESIST SFTY GOGGS SHOULD BE WORN.
NOTE:CONT LENSES POSE SPEC PROBELM; SOFT LENSES MAY ABSORB
IRRITANTS & ALL LENSES CO NC THEM. DO NOT WEAR CONT LENSES IN LAB.
STORE MATL IN COOL, DRY , WELL VENT AREA & PROTECT CNTNRS F ROM
PHYSICAL.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WEAR NIOSH APPRVD AIR-PURIFYING RESP WITH
HIGH-EFFICIENCY PARTICULATE FILTER. SPECIFIC RESP SELECTED MUST BE
BASED ON CONTAM LEVELS FOUND IN WORKPLACE, MUST BE BASED ON
SPECIFIC OPERATION, MUST NOT EX CEED WORKING LIMITS OF RESP & MUST
BE APPRVD BY NIOSH.
Protective Gloves:IMPERVERIOUS GLOVES .
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EMERGENCY EYE WASH & DELUGE SHOWER MEETING
ANSI DESIGN CRITERIA . LAB COATS.
Work Hygienic Practices:NOTE: CONTACT LENSES POSE SPECIAL PROBLEM; SOFT
LENSES MAY ABSORB IRRITANTS & ALL LENSES CONCENTRATE THEM. DO NOT
WEAR CONTACT LENSES IN THE LAB.
Supplemental Safety and Health
SIGNS & SYMPS OF EXPOS: PIGMENTATION. RPTD/PRLNGD EXPOS TO ZINC OXIDE,
COUPLED W/POOR PERSONAL HYGIENE, MAY RSLT IN OXIDE POX DUE TO
CLOGGING OF SEBACEOUS GLANDS. OXIDE POX, ESPECIALLY LOCALIZED TO MO
IST AREAS, IS CHARACT BY SM RED, HARD PROJECTING PAPULES W/CENTRAL
WHITE PLUG, WHICH DEVELOPS (OTHER INFO)
================== Physical/Chemical Properties ==================
Melt/Freeze Pt:=1975.C, ######F
Vapor Density:5.6
Spec Gravity:0.67
pH:6.95-7.37
Solubility in Water:ECOLOGICAL INFORMATION
Appearance and Odor:ODORLESS, WHITE, YELLOWISH-WHITE, OR GRAYISH FINE
OR COARSE (ECOLOGICAL INFO)
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
SEE FIRE AND EXPLOSION HAZARD DATA.
Stability Condition to Avoid:NO ADVERSE CONDITIONS KNOWN FOR THIS
MATERIAL.
Hazardous Decomposition Products:WHEN HEATED AT ELEVATED TEMPERATURES,
ZINC OXIDE SUBLIMES TO PRODUCE TOXIC FUMES.
=================== Toxicological Information ===================
Toxicological Information:OSHA TLV-TWA: 5 MG/M3 (RESP FRACTION), 10
MG/M3 (TOTAL DUST), 5 MG/M3 (FUME), ACGIH TLV-TWA: 5 MG/M3 (FUME)
NIOSH RECOMMENDED TLV-TWA: 5 MG/M3, 15 MG/M3 (CEILING/DUST), 5
MG/M3 (FUME)(MFR). RABBIT, S KIN: 500 MG/24 HOURS (MILD
IRRITATION). RABBIT, EYE: 500 MG/24 HOURS (MILD IRRITATION). RAT,
INTRAPERITONEAL: LD50: 240 MG/KG. MOUSE, INHAL: LC50: 2500 MG/M3.
MOUSE,ORAL: LD50: 7950 MG/KG. HUMAN, INHA L: TCLO: 600 MG/KG.
HUMAN, ORAL: LDLO: 500 MG/KG.
===================== Ecological Information =====================
Ecological:PHYSICAL/CHEMICAL CHARACTERISTICS: SOL IN H*2O: PRACTICALLY
INSOLUBLE IN WATER (1.6 MG/L AT 29C). SOL IN OTHER COMPOUNDS: SOL
IN DILUTE ACETIC/MINERAL ACIDS, AMMONIA, AMMONIUM CHLORIDE,
AMMONIUM SALT SOLNS, FIXED ALKALI HYDROXIDES, AND STRONG BASES.
INSOLUBLE IN ALCOHOL, ETHER & DULUTE SULFURIC ACID. APPEAR/ODOR:
AMORPHOUS POWDER OR HEXAGONAL CRYSTALS, WITH A BITTER TASTE WHICH
GRADUALLY ABSORBS C ARBON DIOXIDE FROM THE AIR.
==================== Disposal Considerations ====================
Waste Disposal Methods:FOLLOW ALL FEDERAL, STATE AND LOCAL REGULATIONS.
=================== MSDS Transport Information ===================
Transport Information:DOT CLASSIFICATION: NOT HAZARDOUS BY DOT
REGULATIONS.
======================= Other Information =======================
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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