MATERIAL SAFETY DATA SHEET
DIXIE CHEMICAL COMPANY, INC.
P.O. Box 130410
Houston, TX 77219-0410
(713) 863-1947
FAX: (713) 863-8316
SECTION 1 鈥? CHEMICAL IDENTIFICATION
Trade Name: Glutaric Anhydride (GAN) Date of Issue: April 8, 1997
Formula: C5H6O3 Revised Date: February 18, 2003
Chemical Family: Anhydrides
Telephone Number: Information (281) 474-3271
Emergency Number: Chemtrec (800) 424-9300
HMIS Hazard Rating 4 = Extreme
Health: 2 3 = High
Fire: 1 2 = Moderate
Reactivity: 1 1 = Slight
PPE rating to be supplied by user 0 = Least
depending on use conditions.
SECTION 2 鈥? COMPOSITION
Components Percentage TLV (ppm) CAS #
Glutaric anhydride >95 N.E. 108-55-4
Note: N.E. = Not Established N/A = Not Applicable
SECTION 3 鈥? HAZARDS IDENTIFICATION
Eye Contact: Severe eye irritant. Contact with even small amounts may lead to severe conjunctivitis
and corneal injury, which if untreated, may result in permanent injury.
Skin Contact: Brief contact is not expected to be irritating. Sustained contact (over one hour) will
result in irritation and possible corrosion of the skin. Prolonged or widespread contact
may result in the absorption of potentially harmful amounts of material. Recurrent
contact may result in dermatitis.
Inhalation: No effects are expected from vapor generated at ambient temperature.
Ingestion: Toxic. Symptoms of exposure include discomfort or burning sensation in the mouth,
throat, chest and abdomen, along with nausea, vomiting, diarrhea, faintness, weakness,
thirst, dizziness, drowsiness, and loss of consciousness. Aspiration into the lungs may
occur during ingestion or vomiting, resulting in lung injury.
Glutaric Anhydride (GAN), Page 2 of 6
SECTION 4 鈥? FIRST AID MEASURES
Eye Contact: Immediately flush with plenty of water for at least 15 minutes. Get medical attention.
Skin Contact: Immediately remove contaminated clothing and shoes. Wipe excess material from
skin and flush with water for at least 15 minutes. Use soap if available or follow by
washing with soap and water. Do not reuse contaminated clothing without
laundering. If irritation persists, seek medical advice.
Inhalation: Remove victim to fresh air. If breathing is difficult, give oxygen. If not breathing,
administer artificial respiration. Get medical attention.
Ingestion: If swallowed, do not induce vomiting. Water may be given to victim. Get medical
attention immediately.
SECTION 5 鈥? FIREFIGHTING MEASURES
Extinguishing Media: Use water, foam, dry chemical, or carbon dioxide (CO2).
Special Firefighting Firefighters should wear NIOSH approved self-contained breathing apparatus.
Procedures/Precautions: Responders should wear protective clothing to prevent skin contact. Move
containers from fire area. If unable to move, cool sealed containers with water.
Unusual Fire and This material is reactive with water, but the reaction will not significantly
Explosion Information: increase fire severity. Water spray can be an effective extinguishing agent if
used in large enough quantity to adequately remove the heat of reaction (20:1
volume ratio or more). Emits acrid smoke and irritating vapors when burning.
Dust/air mixtures may ignite or explode.
Environmental Note: Do not allow contaminated runoff from fire fighting to enter natural waters.
This product may be hazardous to fish.
SECTION 6 鈥? ACCIDENTAL RELEASE MEASURES
Protective Measures: Evacuate area of unprotected personnel. Eliminate sources of ignition. Dust/air
mixtures may ignite or explode. Stay upwind and out of low area鈥檚. Wear personal protective
equipment (See section 8) when responding to spills.
Spill Management: Stop source of leak if safe to do so. Dike and contain spill. Use water spray (fog)
to reduce dust. If dust cloud forms, blanket area with water fog and foam. Clean up with non-sparking
tools. Place in non-leaking container and dispose of material properly. Spray area with water to
remove trace residue. Contain run-off from residue flush and dispose of properly. Prevent entry into
waterways, sewer, or confined areas. Remove contaminated trace residues from soil and dispose of in
same manner as material.
Disposal: Proper disposal should be evaluated based on regulatory status of this material (refer to
section 13).
SECTION 7 鈥? HANDLING AND STORAGE
Dust/air mixtures may ignite or explode. Containers should be grounded and/or bonded when material
is transferred. Store in a cool, dry place. Keep away from heat, sparks, and flames.
Glutaric Anhydride (GAN), Page 3 of 6
SECTION 8 鈥? EXPOSURE CONTROLS AND PERSONAL PROTECTION
Respiratory Protection: NIOSH approved respiratory protection for dust.
Ventilation: Utilize local exhaust to control high dust concentrations in confined areas.
Protective Gloves: Utilize appropriate impervious chemical gloves.
Eye Protection: Chemical goggles and possibly a face shield. Have eyewash facilities readily
available.
Other Protective Wear additional protective clothing to prevent skin contact. This may include
Equipment: chemical resistant boots and chemical resistant suits.
Work Practices: Use good personal hygiene practices. Wash hands before eating, drinking,
smoking or using toilet facilities. Promptly remove soiled clothing and wash
thoroughly before reuse. Shower after work using plenty of soap and water.
SECTION 9 鈥? PHYSICAL AND CHEMICAL PROPERTIES
287oC @ 3 mm Hg
Boiling Point:
51.9oC
Freezing Point:
Volatility/Vol (%): N.E.
<0.1 @ 20oC
Vapor Pressure (mm Hg):
Vapor Density (Air = 1): 3.939
Solubility in H2O: Hydrolyzes to glutaric acid.
Appearance/Odor: Pale yellow, crystalline solid with an acidic odor.
1.236 @ 37oC
Specific Gravity (H2O = 1):
Evap. Rate (Butyl Acetate = 1): N.E.
352oF (178oC) PMCC, ASTM D93, 9612-84
Flash Point:
Lower Explosive Limit: N.E.
Upper Explosive Limit: N.E.
608oF (320oC)
Autoignition Temperature:
SECTION 10 鈥? STABILITY AND REACTIVITY
Chemical Stability: Stable.
Temperatures above 225oC will result in serious evolution of heat and
Conditions to Avoid:
off-gassing. Keep away from heat and open flames.
Incompatible Materials: Water, alcohols, alkalies, oxidizers, and mineral acids.
Decomposition Products: Carbon dioxide and carbon monoxide.
Hazardous Polymerization: Will not occur.
SECTION 11 鈥? TOXICOLOGICAL INFORMATION
ACGIH Glutaric anhydride TLV: N.E. STEL: N.E.
Glutaric Anhydride (GAN), Page 4 of 6
Glutaric acid TLV: N.E. STEL: N.E.
OSHA Glutaric anhydride PEL: N.E. STEL: N.E.
Glutaric acid PEL: N.E. STEL: N.E.
Irritation: glutaric anhydride:
Skin: 0.5 g/4H moderately severe (rabbit) VHTODE 34, 6, 493, 92
Eyes: 10 mg SEV (rabbit) VHTODE 34, 6, 493, 92
Inhalation: glutaric anhydride:
No deaths/saturated atmosphere for 6 hours (rat) VHTODE 34, 6, 493, 92
Ingestion: glutaric anhydride:
LDLo: 4460 mg/kg (rat) AIHAAP 23, 95, 62
LDLo: 0.30 g/kg (female rats) VHTODE 34, 6, 493, 92
LD50: 0.40 g/kg (female rats) VHTODE 34, 6, 493, 92
LD50: 1.41 g/kg (male rats) VHTODE 34, 6, 493, 92
glutaric acid:
LD50: 6000 mg/kg (mouse) BIJOAK 34, 1196, 40
Dermal: glutaric anhydride:
LDLo: 1780 mg/kg (rabbit) AIHAAP 23, 95, 62
LD50: 5.66 g/kg (female rabbits) VHTODE 34, 6, 493, 92
LD50: 6.25 g/kg (male rabbits) VHTODE 34, 6, 493, 92
Glutaric anhydride was not found to be mutagenic in an Ames bacterial assay. Based on animal
experiments, glutaric anhydride is not expected to be a skin sensitizer.
Carcinogenicity listed by: NTP: No IARC: No OSHA: No
SECTION 12 鈥? ECOLOGICAL INFORMATION
No data available.
SECTION 13 鈥? DISPOSAL INFORMATION
Place in a city, state, or federally permitted disposal facility. Handle in accordance with all applicable
regulations.
SECTION 14 鈥? TRANSPORTATION INFORMATION
DOT Shipping Name: Corrosive Solids, Acidic, Organic, n.o.s. (glutaric anhydride),
8, UN 3261, PG III.
SECTION 15 鈥? REGULATORY INFORMATION
U.S. Regulations:
TSCA: All components are listed on the TSCA inventory.
SARA TITLE III
Acute: Yes
Chronic: No
Fire: No
Glutaric Anhydride (GAN), Page 5 of 6
Reactivity: Yes
Pressure: No
TSCA 12(b) Export Notification: Not Listed
California Proposition 65: Not Listed
European Regulations:
EINECS Number: Glutaric Anhydride: 203-593-6
Glutaric Acid: 203-817-2
EC Risk and Safety Phrases:
R21 鈥? Harmful in contact with skin.
R36 鈥? Irritating to eyes.
R37 鈥? Irritating to respiratory system.
R38 鈥? Irritating to skin.
S2 鈥? Keep container out of reach of children.
S13 鈥? Keep away from food, drink and animal feeding stuffs.
S24 鈥? Avoid contact with skin.
S25 鈥? Avoid contact with eyes.
S26 鈥? In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice.
S36 鈥? Wear suitable protective clothing.
S46 鈥? If swallowed, seek medical advice immediately and show this container or label.
Canadian Regulations:
All components are listed on the DSL.
Japanese Regulations:
All components are listed on the ENCS.
ENCS Number: Glutaric Anhydride: 2-3401
Glutaric Acid: 2-2560
Australian Regulations:
All components are listed on the AICS.
Korean Regulations:
All components are not listed on the ECL.
ECL Number: Glutaric Anhydride: Not Listed
Glutaric Acid: KE-27970
SECTION 16 鈥? OTHER INFORMATION
PPE Codes (NPCA-HMIS)
A 鈥? Glasses G 鈥? Glasses, Gloves, Vapor Respirator
B 鈥? Glasses, Gloves H 鈥? Goggles, Gloves, Apron, Vapor Respirator
C 鈥? Glasses, Gloves, Apron I 鈥? Glasses, Gloves, Dust/Vapor Respirator
D 鈥? Faceshield, Gloves, Apron J 鈥? Goggles, Gloves, Apron, Dust/Vapor Respirator
Glutaric Anhydride (GAN), Page 6 of 6
E 鈥? Glasses, Gloves, Dustmask K 鈥? Supplied Air, Gloves, Full Protective Suit, Boots
F 鈥? Glasses, Gloves, Apron, Dust Respirator
Disclaimer
The information contained in the Material Safety Data Sheet is based on technical data that Dixie Chemical
Company believes to be reliable and is provided to our customers at no cost. It is intended for use by persons
having technical skill and at their own discretion and risk. Dixie Chemical Company will assume no liability
in connection with any uses of this information and no warranties, expressed or implied, are made with
regards to this information since conditions of use are outside Dixie Chemical Company鈥檚 control.
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