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MSDS Material Safety Data Sheet
CAS

556-50-3
532-32-1

File Name: vitaldiagnosticsinc_com---MSDS-55350_Rev._C_Envoy_500_GGT_Reagent_Kit.asp
                           MATERIAL SAFETY DATA SHEET
Prepared to U.S. OSHA, CMA, ANSI, and Canadian WHMIS Standards

PART I What is the material and what do I need to know in an emergency?
1. PRODUCT IDENTIFICATION
Envoy庐 500 GGT Reagent Kit
TRADE NAME (AS LABELED):
PRODUCT NUMBER (AS LABELED): 55350
CHEMICAL NAME/CLASS: Not Applicable
SYNONYMS: Not applicable
PRODUCT USE: In-Vitro Diagnostic Reagents
SUPPLIER/MANUFACTURER'S NAME: Vital Diagnostics, Inc.
ADDRESS: 27 Wellington Road
Lincoln, RI 02865 USA
EMERGENCY PHONE: 1-760-602-8700
BUSINESS PHONE: 1-401-642-8400; 1-800-345-2822
DATE OF PREPARATION: August 25, 2007
2. COMPOSITION and INFORMATION ON INGREDIENTS
This Material Safety Data sheet describes the GGT REAGENT KIT. This product consists of the following two reagents: GGT Reagent 1 and GGT Reagent
2.
CHEMICAL NAME CAS # % v/v EXPOSURE LIMITS IN AIR
OTHER
ACGIH-TLV OSHA-PEL NIOSH
TWA STEL TWA STEL IDLH
3 3 3 3 3 3
mg/m mg/m mg/m mg/m mg/m mg/m
COMPONENT 1: GGT REAGENT 1 (F8858 VA)
Glycylglycine 556-50-3 1-5 NE NE NE NE NE NE
Water and other constituents. Each of the other Balance The remaining components do not contribute any significant additional hazards. All
constituents is present in less than 1 percent pertinent information has been provided in this document, per the requirements of the
concentration (0.1% concentration for potential Federal Occupational Safety and Health Administration Standard (29 CFR
carcinogens, reproductive toxins, respiratory tract 1910.1200), U.S. State equivalent Standards, and Canadian Workplace Hazardous
sensitizers, and mutagens). Materials Identification System Standards (CPR 4).

COMPONENT 2: GGT REAGENT 2 (F8859 VA)
NE
Sodium Benzoate 532-32-1 <1 NE NE NE NE NE
Water and other constituents. Each of the other Balance The remaining components do not contribute any significant additional hazards. All
constituents is present in less than 1 percent pertinent information has been provided in this document, per the requirements of the
concentration (0.1% concentration for potential Federal Occupational Safety and Health Administration Standard (29 CFR
carcinogens, reproductive toxins, respiratory tract 1910.1200), U.S. State equivalent Standards, and Canadian Workplace Hazardous
sensitizers, and mutagens). Materials Identification System Standards (CPR 4).
NE = Not Established NIC = Notice of Intended Change See Section 16 for Definitions of Terms Used
NOTE: ALL WHMIS required information is included in appropriate sections based on the ANSI Z400.1-1998 format. This product has been classified in
accordance with the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.




MSDS-55350, Rev. C, DCO: 07-202 Page 1 of 9
3. HAZARD IDENTIFICATION
EMERGENCY OVERVIEW: The components of this product are clear, colorless, odorless liquids, except the GGT
REAGENT 2, which is yellow. Health Hazards: The chief hazard in event of contamination or overexposure to this
product is the potential for irritation of contaminated skin or eyes. Flammability Hazards: If involved in a fire, the
components of this product may decompose to produce toxic gases (e.g., carbon oxides, phosphorus oxides, sodium
oxide, and nitrogen oxides). Reactivity Hazards: Negligible. Environmental Hazards: Negligible. Emergency
Recommendations: Emergency responders must wear personal protective equipment suitable for the situation to which
they are responding.

SYMPTOMS OF OVER EXPOSURE BY ROUTE OF EXPOSURE: No
adverse health effects should occur from routine, occupational use of this HAZARDOUS MATERIAL IDENTIFICATION SYSTEM
product鈥檚 components in the manner specified by the manufacturer's
instructions. The potential health effects of this product鈥檚 components are
(BLUE) 1
as follows: HEALTH HAZARD
INHALATION: Inhalation of vapors, mists, or sprays of this product鈥檚
components may mildly irritate the nose, throat, and lungs. Symptoms may
include coughing and sneezing.
CONTACT WITH SKIN or EYES: Contact with the skin may cause mild FLAMMABILITY HAZARD (RED) 0
irritation, which is alleviated upon rinsing.
SKIN ABSORPTION: The components of this product are not known to be
absorbed through intact skin.
INGESTION: Ingestion is not anticipated to be a significant route of PHYSICAL HAZARD (YELLOW) 0
exposure for this product鈥檚 components. If these components are
swallowed they may cause gastric distress. Large doses may cause
nausea, vomiting, and diarrhea. Sodium Benzoate (a constituent in a
PROTECTIVE EQUIPMENT
component of this product) can cause a food allergy; subsequent
exposures to very small amounts may cause allergic reaction.
INJECTION: Accidental injection of this product鈥檚 components, via EYES HANDS BODY
RESPIRATORY
laceration or puncture by a contaminated object, may cause local redness,
tissue swelling, and discomfort in addition to the wound.
SEE SECTION 8 SEE SECTION 8
HEALTH EFFECTS OR RISKS FROM EXPOSURE: An Explanation in Lay
Terms.
ACUTE: Severe inhalation and ingestion exposure may be irritating. For Routine Use and Handling Applications
CHRONIC: These components are not known to cause any significant
chronic health effects. Sodium Benzoate (a constituent in a component of this product) can cause a food allergy; subsequent
exposures to very small amounts may cause allergic reaction.
TARGET ORGANS: ACUTE: Skin, respiratory system. CHRONIC: None known.




MSDS-55350, Rev. C, DCO: 07-202 Page 2 of 9
PART II What should I do if a hazardous situation occurs?
4. FIRST-AID MEASURES
Victims of chemical exposure must be taken for medical attention. Rescuers should be taken for medical attention if
necessary. Take a copy of label and MSDS to physician or health professional with victim.
SKIN EXPOSURE: Basic hygiene should prevent any problems. If contact with product causes redness, inflammation, or
irritation, flush the exposed area with running water. Remove any contaminated clothing, taking care not to contaminate
eyes.
EYE EXPOSURE: If liquid or vapors of this product鈥檚 components enter the eyes, open victim's eyes while under gently
running water. Use sufficient force to open eyelids. Have victim "roll" eyes. Minimum flushing is for 15 minutes.
INHALATION: If vapors, mists, or sprays of this product鈥檚 components are inhaled, causing irritation, remove victim to fresh
air. If necessary, use artificial respiration to support vital functions. Remove or cover gross contamination to avoid exposure
to rescuers.
INGESTION: If this product鈥檚 components are swallowed, CALL PHYSICIAN OR POISON CONTROL CENTER FOR
MOST CURRENT INFORMATION. If professional advice is not available, do not induce vomiting. Never induce vomiting or
give diluents (milk or water) to someone who is unconscious, having convulsions, or unable to swallow. If vomiting occurs,
lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent
aspiration.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Pre-existing dermatitis, other skin conditions, may be aggravated
by overexposure to components of this product.
RECOMMENDATIONS TO PHYSICIANS: Treat symptoms and eliminate overexposure.
5. FIRE-FIGHTING MEASURES
FLASH POINT: Not flammable.
AUTOIGNITION TEMPERATURE: Not applicable. NFPA RATING
FLAMMABLE LIMITS (in air by volume, %):
FLAMMABILITY
(LEL): Not applicable.
(UEL): Not applicable.
FIRE EXTINGUISHING MATERIALS: In the event of a fire, use suppression 0
methods for surrounding materials.
Water Spray: YES Carbon Dioxide: YES 0 0
HEALTH REACTIVITY
Dry Chemical: YES Halon: YES
Other: Any "ABC" Class. Foam: YES
UNUSUAL FIRE AND EXPLOSION HAZARDS: In a fire situation, this
product presents negligible hazards to fire fighters. When involved in a fire,
this products components will decompose and produce irritating vapors and OTHER
toxic gases (including carbon oxides, phosphorus oxides, sodium oxides, and
nitrogen oxides)
Explosion Sensitivity to Mechanical Impact: Not sensitive
Explosion Sensitivity to Static Discharge: Not sensitive.
SPECIAL FIRE-FIGHTING PROCEDURES: Move containers from fire area if it can be done without risk to personnel.
Incipient fire responders should wear eye protection. Structural firefighters must wear Self-Contained Breathing Apparatus
and full protective equipment. If possible, prevent runoff water from entering storm drains, bodies of water, or other
environmentally sensitive areas.

6. ACCIDENTAL RELEASE MEASURES
SPILL AND LEAK RESPONSE: For small releases take basic hygiene precautions. Lightweight gloves, a lab coat, and eye
protection should be worn. Absorb spilled liquid with suitable absorbent materials. Trained personnel using pre-planned
procedures should respond to large releases that are not immediately controlled. Proper protective equipment should be
used. In case of a spill, clear the affected area, protect people, and respond with trained personnel
In the event of a non-incidental release, minimum Personal Protective Equipment should be Level D: lab-gloves, chemical
resistant apron, boots, and splash goggles. Respiratory protection should not be necessary. Absorb spilled liquid with
polypads or other suitable absorbent materials. Decontaminate the area thoroughly. Place all spill residue in a suitable
container and seal. Dispose of in accordance with applicable U.S. federal, State, or local procedures or appropriate
standards of Canada (see Section 13, Disposal Considerations.)




MSDS-55350, Rev. C, DCO: 07-202 Page 3 of 9
PART III How can I prevent hazardous situations from occurring?
7. HANDLING and STORAGE
WORK PRACTICES AND HYGIENE PRACTICES: As with all chemicals, avoid getting this product鈥檚 components ON YOU
or IN YOU. Wash thoroughly after handling this product鈥檚 components. Avoid splashing or spraying this product鈥檚
components. Do not eat or drink, while handling this product鈥檚 components. Follow SPECIFIC USE INSTRUCTIONS
supplied with this product.
STORAGE AND HANDLING PRACTICES: All employees who handle this material should be trained to handle it safely. Do
NOT pour these solutions down the drain. Open containers slowly on a stable surface. Keep container tightly closed when
not in use. Empty containers may contain residual amounts of this product; therefore, empty containers should be handled
with care. Store away from incompatible materials (see Section 10, Stability and Reactivity).. Store this product in original
containers at controlled temperature 2-8掳C (36-46掳F). Inspect all incoming containers before storage to ensure containers
are properly labeled and not damaged.
PROTECTIVE PRACTICES DURING MAINTENANCE OF CONTAMINATED EQUIPMENT: Follow practices indicated in
Section 6 (Accidental Release Measures). Make certain that application equipment is locked and tagged-out safely as
appropriate. Before maintenance begins, decontaminate equipment thoroughly. Collect all rinsates and dispose of according
to applicable U.S. Federal, State, or local procedures or appropriate standards of Canada. All disposable items
contaminated with this product should be disposed of properly.

8. EXPOSURE CONTROLS - PERSONAL PROTECTION
VENTILATION AND ENGINEERING CONTROLS: Use with adequate ventilation to ensure exposure levels are maintained
below the limits provided in Section 2 (Composition and Information on Ingredients) if applicable. Ensure eyewash/safety
shower stations are available near areas where this product is used.
RESPIRATORY PROTECTION: Respiratory protection is not generally needed during routine use of this product. Maintain
airborne contaminant concentrations below exposure limits listed in Section 2 (Composition and Information on Ingredients) if
applicable. Use only respiratory protection authorized in the U.S. Federal OSHA Respiratory Protection Standard (29 CFR
1910.134), equivalent U.S. State standards, or Canadian CSA Standard Z94.4-93. Use supplied air respiration protection if
oxygen levels are below 19.5% or are unknown.
EYE PROTECTION: Splash goggles or safety glasses. If necessary, refer to U.S. OSHA 29 CFR 1910.133 or equivalent
Canadian Standard.
HAND PROTECTION: Wear latex or rubber gloves for routine industrial use. Use gloves for spill response, as stated in
Section 6 (Accidental Release Measures) of this MSDS.
BODY PROTECTION: Use body protection appropriate for task (e.g., coveralls, Tyvek庐 suit).

9. PHYSICAL and CHEMICAL PROPERTIES
FOR GGT REAGENT 1
RELATIVE VAPOR DENSITY (air = 1): Not established. EVAPORATION RATE (nBuAc = 1): Similar to water.
SPECIFIC GRAVITY (water = 1): 0.999-1.002. FREEZING/MELTING POINT: Similar to water.
VAPOR PRESSURE, mm Hg @ 20掳C: Not established. pH: 6-9
ODOR THRESHOLD: Not available.
APPEARANCE AND COLOR: Clear, colorless liquid.
LOG WATER/OIL DISTRIBUTION COEFFICIENT: Not available.
HOW TO DETECT THIS SUBSTANCE: There are no unusual warning properties associated with these components..
FOR GGT REAGENT 2
RELATIVE VAPOR DENSITY (air = 1): Not established. EVAPORATION RATE (nBuAc = 1): Similar to water.
SPECIFIC GRAVITY (water = 1): Not established. FREEZING/MELTING POINT: Similar to water.
VAPOR PRESSURE, mm Hg @ 20掳C: Not established. pH: 4-6
ODOR THRESHOLD: Not available. APPEARANCE AND COLOR: Clear, yellow liquid.
LOG WATER/OIL DISTRIBUTION COEFFICIENT: Not available.
HOW TO DETECT THIS SUBSTANCE: There are no unusual warning properties associated with these components

10. STABILITY and REACTIVITY
STABILITY: Stable.
DECOMPOSITION PRODUCTS: Thermal decomposition of this product鈥檚 components may produce carbon oxides and
nitrogen oxides.
MATERIALS WITH WHICH SUBSTANCE IS INCOMPATIBLE: Strong oxidizers, strong acids, some metals, substances
that are incompatible with water.
HAZARDOUS POLYMERIZATION: Will not occur.
CONDITIONS TO AVOID: Any conditions that are incompatible with water, mixing this product with incompatible chemicals.


MSDS-55350, Rev. C, DCO: 07-202 Page 4 of 9
PART IV Is there any other useful information about this material?
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA: The following information is available for the constituents in components of this product present in greater
that 1 percent concentration.
GLYCYLGLYCINE:
Currently, there are no toxicological data available for this compound.
SUSPECTED CANCER AGENT: The constituents in this product鈥檚 components are not found on the following lists: NTP,
IARC, FEDERAL OSHA Z-List, and CAL-OSHA and therefore are neither considered to be nor suspected to be cancer
causing agents by these agencies.
IRRITANCY OF PRODUCT: Contact with the skin or eyes may cause mild irritation, which is alleviated upon rinsing.
SENSITIZATION TO THE PRODUCT: The components of this product are not known to cause skin or respiratory
sensitization.
REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects of this product and its
components on the human reproductive system.
Mutagenicity: This product is not reported to produce mutagenic effects in humans
Embryotoxicity: This product is not reported to cause human embryotoxic effects.
Teratogenicity: This product is not reported to cause teratogenic effects in humans.
Reproductive Toxicity: This product is not reported to cause adverse reproductive effects in humans
A mutagen is a chemical that causes permanent changes to genetic material (DNA) such that the changes will propagate
through generation lines. An embryotoxin is a chemical that causes damage to a developing embryo (i.e. within the first eight
weeks of pregnancy in humans), but the damage does not propagate across generational lines. A teratogen is a chemical
that causes damage to a developing fetus, but the damage does not propagate across generational lines. A reproductive
toxin is any substance that interferes in any way with the reproductive process.
BIOLOGICAL EXPOSURE INDICES: Currently, there are no Biological Exposure Indices (BEIs) determined for the
constituents in this product鈥檚 components.

12. ECOLOGICAL INFORMATION
ALL WORK PRACTICES MUST BE AIMED AT ELIMINATING ENVIRONMENTAL CONTAMINATION.
ENVIRONMENTAL STABILITY: The components of this product will degrade in the environment into smaller organic and
inorganic constituents.
EFFECT OF MATERIAL ON PLANTS or ANIMALS: Release of large quantities of this product鈥檚 components into the
environment may have adverse effects on plants or animals.
EFFECT OF CHEMICAL ON AQUATIC LIFE: Release of large quantities of this product鈥檚 components into the environment
may have adverse effects on plants or animals.

13. DISPOSAL CONSIDERATIONS
PREPARING WASTES FOR DISPOSAL: Waste disposal must be in accordance with appropriate U.S. Federal, State, and
local regulations or with regulations of Canada. This product, if unaltered by use, may be disposed of by treatment at a
permitted facility or as advised by your local hazardous waste regulatory authority. Do NOT pour these solutions down the
drain.
U.S. EPA WASTE NUMBER: Not applicable to wastes consisting only of this product.

14. TRANSPORTATION INFORMATION
THIS PRODUCT IS NOT HAZARDOUS AS DEFINED BY 49 CFR 172.101 BY THE U.S. DEPARTMENT OF
TRANSPORTATION..
PROPER SHIPPING NAME: Not Regulated
HAZARD CLASS NUMBER and DESCRIPTION: Not Applicable
UN IDENTIFICATION NUMBER: Not Applicable
PACKING GROUP: Not Applicable.
DOT LABEL(S) REQUIRED: Not Applicable
EMERGENCY RESPONSE GUIDEBOOK NUMBER (2000): Not Applicable
MARINE POLLUTANT: Not applicable (49 CFR 172.101, Appendix B).
TRANSPORT CANADA TRANSPORTATION OF DANGEROUS GOODS REGULATIONS: This product is considered as
Dangerous Goods, per regulations of Transport Canada.
SPECIAL PROVISIONS: 65
EXPLOSIVE LIMIT & LIMITED QUANTITY INDEX: 0
ERAP INDEX: None
PASSENGER CARRYING SHIP INDEX: None
PASSENGER CARRYING ROAD OR RAIL VEHICLE INDEX: 10
MARINE POLLUTANT: Not applicable

MSDS-55350, Rev. C, DCO: 07-202 Page 5 of 9
14. TRANSPORTATION INFORMATION (Continued)
TRANSPORT CANADA TRANSPORTATION OF DANGEROUS GOODS REGULATIONS: The individual components are
further defined per regulations of Transport Canada. The use of the above U.S. DOT information from the U.S. 49 CFR
regulations is allowed for shipments that originate in the U.S. For shipments via ground vehicle or rail that originate in
Canada, the following information is applicable.
15. REGULATORY INFORMATION
ADDITIONAL UNITED STATES REGULATIONS:
U.S. SARA REPORTING REQUIREMENTS: The constituents in this product鈥檚 components of are not subject to Sections
302, 304, and 313 reporting requirements under the Superfund Amendment and Reauthorization Act as follows:
U.S. SARA THRESHOLD PLANNING QUANTITY: There are no specific Threshold Planning Quantities for this product. The
default Federal MSDS submission and inventory requirement filing threshold of 10,000 lb (4,540 kg) may apply, per 40 CFR
370.20.
U.S. CERCLA REPORTABLE QUANTITY (RQ): Not applicable.
U.S. TSCA INVENTORY STATUS: This product is regulated by the Food and Drug Administration; it is exempt from the
requirements of TSCA.
OTHER U.S. FEDERAL REGULATIONS: Not applicable.
U.S. STATE REGULATORY INFORMATION: Components of this product listed in Section 2 (Composition and Information
on Ingredients) are covered under State regulations, as denoted below:
Alaska - Designated Toxic and Hazardous North Dakota - List of Hazardous Chemicals, Pennsylvania - Hazardous Substance List:
No.
Substances: No. Reportable Quantities: No.
Rhode Island - Hazardous Substance List:
California - Permissible Exposure Limits for Minnesota - List of Hazardous Substances:
No.
No.
Chemical Contaminants: No.
Texas - Hazardous Substance List: No.
Missouri - Employer Information/Toxic
Florida - Substance List: No.
West Virginia - Hazardous Substance List:
Substance List: No.
Illinois - Toxic Substance List: No.
No.
New Jersey - Right to Know Hazardous
Kansas - Section 302/313 List: No.
Wisconsin - Toxic and Hazardous
Substance List: No
Massachusetts - Substance List: No.
Substances: No.
Michigan - Critical Materials Register: No.
CALIFORNIA SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT (PROPOSITION 65): No component of this
product is on the California Proposition 65 lists.
U.S. ANSI STANDARD LABELING (Z129.1): CAUTION! MAY CAUSE SKIN AND EYE IRRITATION. Do not taste or
swallow. Avoid skin and eye contact. Avoid prolonged or repeated skin contact. Avoid breathing mists or sprays. Keep
container closed. Use only with adequate ventilation. Wash thoroughly after handling. Wear gloves and goggles. FIRST
AID. In case of contact, immediately flush skin or eyes with plenty of water. If inhaled, remove to fresh air. If ingested, do
not induce vomiting. Get medical attention if necessary. IN CASE OF FIRE: Use water fog, dry chemical, CO2, or 鈥渁lcohol鈥?
foam. IN CASE OF SPILL: Absorb spill with polypads and place in a suitable container. Consult Material Safety Data Sheet
for additional information.
ADDITIONAL CANADIAN REGULATIONS:
CANADIAN DSL/NDSL STATUS: The components of this product are listed on the DSL Inventory.
CANADIAN WHMIS IDL DISCLOSURE STATUS: The Boric Acid component of this product has a disclosure requirement
level of greater than 1%.
OTHER CANADIAN REGULATIONS: Not applicable.
CANADIAN ENVIRONMENTAL PROTECTION AGENCY (CEPA) PRIORITY SUBSTANCES LISTS: The components of
this product are not on the Priority Substances Lists.
WHMIS SYMBOLS: Not Applicable




MSDS-55350, Rev. C, DCO: 07-202 Page 6 of 9
16. OTHER INFORMATION
DEFINITIONS OF TERMS
A large number of abbreviations and acronyms appear on a MSDS. Some of these, which are commonly used, include the following:
CAS #: This is the Chemical Abstract Service Number that uniquely HAZARDOUS MATERIALS IDENTIFICATION SYSTEM
identifies each constituent. HAZARD RATINGS: This rating system was developed by the National
Paint and Coating Association and has been adopted by industry to identify
EXPOSURE LIMITS IN AIR:
the degree of chemical hazards.
CEILING LEVEL: The concentration that shall not be exceeded during any
HEALTH HAZARD:
part of the working exposure.
0 (Minimal Hazard: No significant health risk, irritation of skin or eyes not
IDLH-Immediately Dangerous to Life and Health: This level represents a
anticipated. Skin Irritation: Essentially non-irritating. PII or Draize = 鈥?0鈥?.
concentration from which one can escape within 30-minutes without
Eye Irritation: Essentially non-irritating, or minimal effects which clear in <
suffering escape-preventing or permanent injury.
24 hours [e.g. mechanical irritation]. Draize = 鈥?0鈥?. Oral Toxicity LD50 Rat: <
LOQ: Limit of Quantitation.
5000 mg/kg. Dermal Toxicity LD50Rat or Rabbit: < 2000 mg/kg. Inhalation
MAK: Federal Republic of Germany Maximum Concentration Values in the
Toxicity 4-hrs LC50 Rat: < 20 mg/L.); 1 (Slight Hazard: Minor reversible
workplace.
Injury may occur; slightly or mildly irritating. Skin Irritation: Slightly or mildly
NE: Not Established. When no exposure guidelines are established, an
irritating. Eye Irritation: Slightly or mildly irritating. Oral Toxicity LD50 Rat: >
entry of NE is made for reference.
500-5000 mg/kg. Dermal Toxicity LD50Rat or Rabbit: > 1000-2000 mg/kg.
NIC: Notice of Intended Change.
Inhalation Toxicity LC50 4-hrs Rat: > 2-20 mg/L); 2 (Moderate Hazard:
NIOSH CEILING: The exposure that shall not be exceeded during any part
Temporary or transitory injury may occur. Skin Irritation: Moderately
of the workday. If instantaneous monitoring is not feasible, the ceiling shall
irritating; primary irritant; sensitizer. PII or Draize > 0, < 5. Eye Irritation:
be assumed as a 15-minute TWA exposure (unless otherwise specified)
Moderately to severely irritating and/or corrosive; reversible corneal opacity;
that shall not be exceeded at any time during a workday.
corneal involvement or irritation clearing in 8-21 days. Draize > 0, < 25.
NIOSH RELs: NIOSH鈥檚 Recommended Exposure Limits.
Oral Toxicity LD50 Rat: > 50-500 mg/kg. Dermal Toxicity LD50Rat or Rabbit:
PEL-Permissible Exposure Limit: OSHA鈥檚 Permissible Exposure Limits.
> 200-1000 mg/kg. Inhalation Toxicity LC50 4-hrs Rat: > 0.5-2 mg/L.); 3
This exposure value means exactly the same as a TLV, except that it is
(Serious Hazard: Major injury likely unless prompt action is taken and
enforceable by OSHA. The OSHA Permissible Exposure Limits are based
medical treatment is given; high level of toxicity; corrosive. Skin Irritation:
in the 1989 PELs and the June, 1993 Air Contaminants Rule (Federal
Severely irritating and/or corrosive; may destroy dermal tissue, cause skin
Register: 58: 35338-35351 and 58: 40191). Both the current PELs and the
burns, dermal necrosis. PII or Draize > 5-8 with destruction of tissue. Eye
vacated PELs are indicated. The phrase, 鈥淰acated 1989 PEL,鈥? is placed
Irritation: Corrosive, irreversible destruction of ocular tissue; corneal
next to the PEL that was vacated by Court Order.
involvement or irritation persisting for more than 21 days. Draize > 80 with
SKIN: Used when a there is a danger of cutaneous absorption.
effects irreversible in 21 days. Oral Toxicity LD50 Rat: > 1-50 mg/kg.
STEL-Short Term Exposure Limit: Short Term Exposure Limit, usually a Dermal Toxicity LD50Rat or Rabbit: > 20-200 mg/kg. Inhalation Toxicity
15-minute time-weighted average (TWA) exposure that should not be
LC50 4-hrs Rat: > 0.05-0.5 mg/L.); 4 (Severe Hazard: Life-threatening;
exceeded at any time during a workday, even if the 8-hr TWA is within the
major or permanent damage may result from single or repeated exposure.
TLV-TWA, PEL-TWA or REL-TWA.
Skin Irritation: Not appropriate. Do not rate as a 鈥?4鈥?, based on skin irritation
TLV-Threshold Limit Value: An airborne concentration of a substance alone. Eye Irritation: Not appropriate. Do not rate as a 鈥?4鈥?, based on eye
that represents conditions under which it is generally believed that nearly all irritation alone. Oral Toxicity LD50 Rat: < 1 mg/kg. Dermal Toxicity LD50Rat
workers may be repeatedly exposed without adverse effect. The duration or Rabbit: < 20 mg/kg. Inhalation Toxicity LC50 4-hrs Rat: < 0.05 mg/L).
must be considered, including the 8-hour.
TWA-Time Weighted Average: Time Weighted Average exposure
concentration for a conventional 8-hr (TLV, PEL) or up to a 10-hr (REL)
workday and a 40-hr workweek.




MSDS-55350, Rev. C, DCO: 07-202 Page 7 of 9
DEFINITIONS OF TERMS (Continued)
HAZARDOUS MATERIALS IDENTIFICATION SYSTEM HAZARDOUS MATERIALS IDENTIFICATION SYSTEM
HAZARD RATINGS (continued): HAZARD RATINGS (continued):
FLAMMABILITY HAZARD: PHYSICAL HAZARD (continued):
0 (Minimal Hazard-Materials that will not burn in air when exposure to a 2 (Water Reactivity: Materials that may react violently with water. Organic
Peroxides: Materials that, in themselves, are normally unstable and will
temperature of 815.5掳C [1500掳F] for a period of 5 minutes.); 1 (Slight
readily undergo violent chemical change, but will not detonate. These
Hazard-Materials that must be pre-heated before ignition can occur.
materials may also react violently with water. Explosives: Division 1.4 鈥?
Material require considerable pre-heating, under all ambient temperature
Explosive substances where the explosive effect are largely confined to the
conditions before ignition and combustion can occur, Including: Materials
package and no projection of fragments of appreciable size or range are
that will burn in air when exposed to a temperature of 815.5掳C (1500掳F) for
expected. An external fire must not cause virtually instantaneous explosion
a period of 5 minutes or less; Liquids, solids and semisolids having a flash
of almost the entire contents of the package. Compressed Gases:
point at or above 93.3掳C [200掳F] (e.g. OSHA Class IIIB, or; Most ordinary
Pressurized and meet OSHA definition but < 514.7 psi absolute at 21.1掳C
combustible materials [e.g. wood, paper, etc.]; 2 (Moderate Hazard-
(70掳F) [500 psig]. Pyrophorics: No Rating. Oxidizers: Packing Group II
Materials that must be moderately heated or exposed to relatively high
Solids: any material that, either in concentration tested, exhibits a mean
ambient temperatures before ignition can occur. Materials in this degree
burning time of less than or equal to the mean burning time of a 2:3
would not, under normal conditions, form hazardous atmospheres in air, but
potassium bromate/cellulose mixture and the criteria for Packing Group I
under high ambient temperatures or moderate heating may release vapor in
are not met. Liquids: any material that exhibits a mean pressure rise time
sufficient quantities to produce hazardous atmospheres in air, Including:
less than or equal to the pressure rise of a 1:1 aqueous sodium chlorate
Liquids having a flash-point at or above 37.8掳C [100掳F] Solid materials in
solution (40%)/cellulose mixture and the criteria for Packing Group I are not
the form of course dusts that may burn rapidly but that generally do not form
met. Unstable Reactives: Substances that may polymerize, decompose,
explosive atmospheres; Solid materials in a fibrous or shredded form that
condense, or self-react at ambient temperature and/or pressure, but have a
may burn rapidly and create flash fire hazards (e.g. cotton, sisal, hemp;
low potential for significant heat generation or explosion. Substances that
Solids and semisolids that readily give off flammable vapors.); 3 (Serious
readily form peroxides upon exposure to air or oxygen at room
Hazard- Liquids and solids that can be ignited under almost all ambient
temperature); 3 (Water Reactivity: Materials that may form explosive
temperature conditions. Materials in this degree produce hazardous
reactions with water. Organic Peroxides: Materials that are capable of
atmospheres with air under almost all ambient temperatures, or, unaffected
detonation or explosive reaction, but require a strong initiating source, or
by ambient temperature, are readily ignited under almost all conditions,
must be heated under confinement before initiation; or materials that react
including: Liquids having a flash point below 22.8掳C [73掳F] and having a
explosively with water. Explosives: Division 1.2 鈥? Explosive substances
boiling point at or above 38掳C [100掳F] and below 37.8掳C [100掳F] [e.g.
that have a fire hazard and either a minor blast hazard or a minor projection
OSHA Class IB and IC]; Materials that on account of their physical form or
hazard or both, but do not have a mass explosion hazard. Compressed
environmental conditions can form explosive mixtures with air and are
Gases: Pressure > 514.7 psi absolute at 21.1掳C (70掳F) [500 psig].
readily dispersed in air [e.g., dusts of combustible solids, mists or droplets
Pyrophorics: No Rating. Oxidizers: Packing Group I Solids: any material
of flammable liquids]; Materials that burn extremely rapidly, usually by
that, in either concentration tested, exhibits a mean burning time less than
reason of self-contained oxygen [e.g. dry nitrocellulose and many organic
the mean burning time of a 3.:2 potassium bromate/cellulose mixture.
peroxides]); 4 (Severe Hazard-Materials that will rapidly or completely
Liquids: Any material that spontaneously ignites when mixed with cellulose
vaporize at atmospheric pressure and normal ambient temperature or that
in a 1:1 ratio, or which exhibits a mean pressure rise time less than the
are readily dispersed in air, and which will burn readily, including:
pressure rise time of a 1:1 perchloric acid (50%)/cellulose mixture.
Flammable gases; Flammable cryogenic materials; Any liquid or gaseous
Unstable Reactives: Substances that may polymerize, decompose,
material that is liquid while under pressure and has a flash point below
condense or self-react at ambient temperature and/or pressure and have a
22.8掳C [73掳F] and a boiling point below 37.8掳C [100掳F] [e.g. OSHA Class
moderate potential to cause significant heat generation or explosion.);. 4
IA; Material that ignite spontaneously when exposed to air at a temperature
(Water Reactivity: Materials that react explosively with water without
of 54.4掳C [130掳F] or below [e.g. pyrophoric]).
requiring heat or confinement. Organic Peroxides: Materials that are readily
PHYSICAL HAZARD:
capable of detonation or explosive decomposition at normal temperature
0 (Water Reactivity: Materials that do not react with water. Organic
and pressures. Explosives: Division 1.1 & 1.2-explosive substances that
Peroxides: Materials that are normally stable even under fire conditions
have a mass explosion hazard or have a projection hazard. A mass
and will not react with water. Explosives: Substances that are Non-
explosion is one that affects almost the entire load instantaneously.
Explosive. Unstable Compressed Gases: No Rating. Pyrophorics: No
Compressed Gases: No Rating. Pyrophorics: Add to the definition of
Rating. Oxidizers: No 鈥?0鈥? rating allowed. Unstable Reactives: Substances
Flammability 鈥?4鈥?. Oxidizers: No 鈥?4鈥? rating. Unstable Reactives:
that will not polymerize, decompose, condense or self-react.); 1 (Water
Substances that may polymerize, decompose, condense or self-react at
Reactivity: Materials that change or decompose upon exposure to moisture.
ambient temperature and/or pressure and have a high potential to cause
Organic Peroxides: Materials that are normally stable, but can become
significant heat generation or explosion.). PPE Rating B: Hand and eye
unstable at high temperatures and pressures. These materials may react
protection is required for routine chemical use. PPE Rating C: Hand, eye,
with water, but will not release energy. Explosives: Division 1.5 & 1.6
and body protection may be required for routine chemical use.
substances that are very insensitive explosives or that do not have a mass
NATIONAL FIRE PROTECTION ASSOCIATION HAZARD
explosion hazard. Compressed Gases: Pressure below OSHA definition.
RATINGS:
Pyrophorics: No Rating. Oxidizers: Packaging Group III; Solids: any
HEALTH HAZARD: 0 (material that on exposure under fire conditions would
material that in either concentration tested, exhibits a mean burning time
offer no hazard beyond that of ordinary combustible materials); 1 (materials
less than or equal to the mean burning time of a 3:7 potassium
that on exposure under fire conditions could cause irritation or minor
bromate/cellulose mixture and the criteria for Packing Group I and II are not
residual injury); 2 (materials that on intense or continued exposure under
met. Liquids: any material that exhibits a mean pressure rise time less
fire conditions could cause temporary incapacitation or possible residual
than or equal to the pressure rise time of a 1:1 nitric acid (65%)/cellulose
injury); 3 (materials that can on short exposure could cause serious
mixture and the criteria for Packing Group I and II are not met. Unstable
Reactives: Substances that may decompose, condense or self-react, but temporary or residual injury); 4 (materials that under very short exposure
only under conditions of high temperature and/or pressure and have little or could cause death or major residual injury).
no potential to cause significant heat generation or explosive hazard. FLAMMABILITY HAZARD AND REACTIVITY HAZARD: Refer to
Substances that readily undergo hazardous polymerization in the absence definitions for 鈥淗azardous Materials Identification System鈥?.
of inhibitors.);




MSDS-55350, Rev. C, DCO: 07-202 Page 8 of 9
DEFINITIONS OF TERMS (Continued)
FLAMMABILITY LIMITS IN AIR: Much of the information related to fire ECOLOGICAL INFORMATION:
and explosion is derived from the National Fire Protection Association EC is the effect concentration in water. BCF = Bioconcentration Factor,
which is used to determine if a substance will concentrate in lifeforms which
(NFPA). Flash Point - Minimum temperature at which a liquid gives off
sufficient vapors to form an ignitable mixture with air. Autoignition consume contaminated plant or animal matter. TLm = median threshold
Temperature: The minimum temperature required to initiate combustion in limit; Coefficient of Oil/Water Distribution is represented by log Kow or log
air with no other source of ignition. LEL - the lowest percent of vapor in air, Koc and is used to assess a substance鈥檚 behavior in the environment.
by volume, that will explode or ignite in the presence of an ignition source. REGULATORY INFORMATION:
UEL - the highest percent of vapor in air, by volume, that will explode or U.S. and CANADA:
ignite in the presence of an ignition source. This section explains the impact of various laws and regulations on the
material. ACGIH: American Conference of Governmental Industrial
TOXICOLOGICAL INFORMATION:
Hygienists, a professional association which establishes exposure limits.
Human and Animal Toxicology: Possible health hazards as derived from
EPA is the U.S. Environmental Protection Agency. NIOSH is the National
human data, animal studies, or from the results of studies with similar
Institute of Occupational Safety and Health, which is the research arm of
compounds are presented. Definitions of some terms used in this section
the U.S. Occupational Safety and Health Administration (OSHA). WHMIS
are: LD50 - Lethal Dose (solids & liquids) which kills 50% of the exposed
is the Canadian Workplace Hazardous Materials Information System. DOT
animals; LC50 - Lethal Concentration (gases) which kills 50% of the
and TC are the U.S. Department of Transportation and the Transport
exposed animals; ppm concentration expressed in parts of material per
3
Canada, respectively. Superfund Amendments and Reauthorization Act
million parts of air or water; mg/m concentration expressed in weight of
(SARA); the Canadian Domestic/Non-Domestic Substances List
substance per volume of air; mg/kg quantity of material, by weight,
(DSL/NDSL); the U.S. Toxic Substance Control Act (TSCA); Marine
administered to a test subject, based on their body weight in kg. Other
Pollutant status according to the DOT; the Comprehensive Environmental
measures of toxicity include TDLo, the lowest dose to cause a symptom
Response, Compensation, and Liability Act (CERCLA or Superfund); and
and TCLo the lowest concentration to cause a symptom; TDo, LDLo, and
various state regulations. This section also includes information on the
LDo, or TC, TCo, LCLo, and LCo, the lowest dose (or concentration) to
precautionary warnings which appear on the material鈥檚 package label.
cause lethal or toxic effects. Cancer Information: The sources are: IARC
OSHA - U.S. Occupational Safety and Health Administration.
- the International Agency for Research on Cancer; NTP - the National
EUROPEAN: EC is the European Community (formerly known as the
Toxicology Program, RTECS - the Registry of Toxic Effects of Chemical
EEC, European Economic Community). EINECS: This the European
Substances, OSHA and CAL/OSHA. IARC and NTP rate chemicals on a
Inventory of Now-Existing Chemical Substances. The ARD is the European
scale of decreasing potential to cause human cancer with rankings from 1
Agreement Concerning the International Carriage of Dangerous Goods by
to 4. Subrankings (2A, 2B, etc.) are also used. Other Information: BEI -
Road and the RID are the International Regulations Concerning the
ACGIH Biological Exposure Indices, represent the levels of determinants
Carriage of Dangerous Goods by Rail. AUSTRALIAN: AICS is the
which are most likely to be observed in specimens collected from a healthy
worker who has been exposed to chemicals to the same extent as a worker Australian Inventory of Chemical Substances. NOHSC: National
with inhalation exposure to the TLV. Occupational Health & Safety Code.




MSDS-55350, Rev. C, DCO: 07-202 Page 9 of 9

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