MATERIAL SAFETY DATA SHEET
1 CHEMICAL PRODUCT & COMPANY IDENTIFICATION
TRADE NAME BUTYRIC ACID, SODIUM SALT
CAS NUMBER 156-54-7
ROI NUMBER 1235B
SYNONYMS Sodium butyrate
Research Organics
MANUFACTURER/
4353 E 49th Street
SUPPLIER
Cleveland, Ohio
44125 USA
TELEPHONE NUMBERS - 24 HOUR EMERGENCY ASSISTANCE:
INFOTRAC 800-535-5053
TELEPHONE NUMBERS - GENERAL ASSISTANCE:
Product Information 800-321-0570
2 COMPOSITION / INFORMATION ON INGREDIENTS
Ingredient CAS Number Percentage* Exposure Limits/Health Hazards
Butyric acid, sodium salt 156-54-7 >=98 % IRRITANT. MAY BE HARMFUL.
POSSIBLE MUTAGEN.
% No Exposure limits established by OSHA or
ACGIH
*Values do not reflect absolute minimums and maximums; those values may vary from time to time.
3 HAZARDS IDENTIFICATION
Emergency Overview
CAUTION!
IRRITANT - IRRITATING TO THE SKIN, EYES, AND UPPER RESPIRATORY TRACT.
MAY BE HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN
Potential Health Effects Skin
IRRITANT.
This material will cause skin irritation, resulting in reddening, itching, and inflammation.
May be absorbed through the skin.
Potential Health Effect Eyes
IRRITANT.
Direct contact will cause irritation, redness, tearing and blurred vision.
Potential Health Effects Inhalation
IRRITANT.
Inhalation of this material will cause irritation to the mucous membranes and upper respiratory tract.
This material may cause injury or illness if inhaled.
Effective Date: 11/18/2004 ND = No Data NA = Not Applicable Replaces Sheet Dated 10/24/2000 Page 1 of 6
Catalog Number 1235B Trade Name BUTYRIC ACID, SODIUM SALT
Potential Health Effect Ingestion
If ingested, this material may cause irritation to the mouth, throat and gastrointestinal tract.
May be harmful if swallowed.
Special Toxic Effects
Limited laboratory experiments have shown mutagenic effects. Further testing is required before classifying this
material as a mutagen. See Section 11 of this MSDS for more information.
CAUTION! THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT BEEN FULLY INVESTIGATED.
Target Organs
ND
4 FIRST AID MEASURES
Skin
Immediately flush skin with plenty of water, for at least 15 minutes, while removing contaminated clothing and
shoes. Contaminated clothing must be laundered before reuse. Get medical attention if irritation develops or
persists.
Eyes
Flush immediately with large amounts of water for at least 20 minutes. Eyelids should be held away from the
eyeball to ensure thorough rinsing. Do not allow victim to rub the affected eye(s).
Get medical attention if irritation persists.
Inhalation
Safely remove victim to fresh air. If not breathing, institute artificial respiration/rescue breathing. If breathing is
difficult, ensure clear airway and give oxygen.
Get medical attention.
Ingestion
If swallowed, wash out mouth with water provided person is conscious.
Never give anything by mouth to an unconscious person.
Get medical attention.
5 FIRE FIGHTING MEASURES
Hazardous Combustion Products
MAY EMIT TOXIC AND/OR IRRITATING FUMES UNDER FIRE CONDITIONS.
Extinguishing Media
Use a water spray, dry chemical, alcohol foam, all purpose foam or carbon dioxide to extinguish fire.
Basic Fire Fighting Procedure
As in any fire, wear self-contained breathing apparatus pressure-demand, (MSHA/NIOSH approved or equivalent)
and full protective gear. Evacuate the area and fight fire from a safe distance.
Unusual Fire and Explosion Hazards
None known to manufacturer.
ND (Solid)
Flash Point Temperature
ND
Autoignition Temperature
ND
Flammability Limits in Air Lower
ND
Flammability Limits in Air Upper
6 ACCIDENTAL RELEASE MEASURES
Emergency Action
Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind. (See Personal Protection
Information Section.)
Effective Date: 11/18/2004 ND = No Data NA = Not Applicable Replaces Sheet Dated 10/24/2000 Page 2 of 6
Catalog Number 1235B Trade Name BUTYRIC ACID, SODIUM SALT
Environmental Precautions
Isolate hazard area and deny entry. Keep unnecessary people away. Take immediate steps to stop and contain
the spill. Caution should be exercised regarding personnel safety and exposure to the spilled material.
Spill or Leak Procedure
Vacuum or sweep up material and place in a disposal container. Clean up spills immediately under quailfied
supervision observing precautions in Protective Equipment section. Avoid clean up procedures that generate dust
or result in water pollution.
After removal, scrub the contaminated area with detergent and flush thoroughly with water. Absorb wash liquid
and place in the disposable container. Do not flush to sewer. Avoid runoff into storm sewers and ditches which
lead to waterways.
7 HANDLING AND STORAGE
Handling
Use only in a well ventilated area. Avoid inhalation and contact with skin,eyes and on clothing. Empty containers
may contain material residue. Do not reuse. Do not eat, drink or smoke in areas of use or storage.
Minimize dust generation during handling and contact.
Wash hands thoroughly before eating, drinking or smoking.
Storage
Store at room temperature.
Keep containers tightly closed and upright when not in use.
Storage Hazards
Store away from oxidizers.
8 EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Contols
Facilities using or storing this material must be equipped with an eyewash station and safety shower.
Local exhaust ventilation, process enclosures, and other forms of engineering controls are the preferred means for
controlling exposures.
Eye Protection PPE
Do not wear contact lenses when working with this substance.
Avoid eye contact with this material. Wear chemical safety goggles.
Skin Protection PPE
Avoid skin contact with this material. Use appropriate chemical protective gloves when handling.
Showering and changing into street clothing after work is recommended.
Respiratory Protection PPE
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne levels below
recommended exposure limits.
A NIOSH approved dust respirator should be used as a precautionary measure when airborne contaminants may
occur.
Contact the manufacturer of your respiratory protection equipment for further information and/or recommendations.
A respiratory protection program that meets OSHA 1910.134 requirements must be followed whenever workplace
conditions warrant a respirators use.
9 PHYSICAL AND CHEMICAL PROPERTIES
Appearance
WHITE TO OFF-WHITE POWDER
Boiling Point ND
Melting Point 250 - 253C
Freezing Point ND
Vapor Density ND
Vapor Pressure
Effective Date: 11/18/2004 ND = No Data NA = Not Applicable Replaces Sheet Dated 10/24/2000 Page 3 of 6
Catalog Number 1235B Trade Name BUTYRIC ACID, SODIUM SALT
Vapor Pressure ND
Specific Gravity ND
Molecular Formula C4H7NaO2
Molecular Weight 110.1
pH ND
10 STABILITY REACTIVITY
Stability/Incompatibility
Stable under normal conditions of use.
Incompatible with strong oxidizing agents.
Decomposition Products
Combustion may produce CO, CO2, and/or Sodium Oxides.
Hazardous Polymerization
Will not occur.
11 TOXICOLOGICAL INFORMATION
MUTATION DATA:
Morphological transformation - Human Cells (not otherwise specified) = 2 mmol/L.
DNA Damage - Human HeLa cell = 5 mmol/L.
DNA Inhibition - Human Fibroblast = 5 mmol/L. DNA Inhibition - Human HeLa cell = 5 mmol/L.
Only selected toxicological data is presented here. See actual entry in RTECS for complete information.
CAUTION! THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT BEEN FULLY
INVESTIGATED. FOLLOW GOOD LABORATORY PRACTICES WHEN HANDLING.
Routes of Exposure
Inhalation, ingestion, skin and eye contact.
LD50
REGISTRY OF THE TOXIC EFFECTS OF CHEMICAL SUBSTANCES(RTECS)
RTECS # ET6400000
NO ORAL LD50 IN RATS INFORMATION IS AVAILABLE.
Only selected data is presented here. See actual entry in RTECS for complete information.
Carcinogenicity
NOT LISTED BY IARC, NTP OR OSHA AS A CARCINOGEN
12 ECOLOGICAL INFORMATION
EcoToxicological Information
DATA NOT YET AVAILABLE.
Chemical Fate Information
DATA NOT YET AVAILABLE.
13 DISPOSAL CONSIDERATIONS
Waste Disposal
Under RCRA, it is the responsibility of the user of the product to determine, at the time of disposal, whether the
product meets RCRA criteria for hazardous waste.
If the material is determined to be a hazardous waste, the transportation, storage, treatment and disposal of this
waste material must be conducted in compliance with 40 CFR 262, 263, 264, 268 and 270. Disposal can occur
only in properly permitted facilities.
Contact your local disposal service provider(s) for appropriate method(s) of disposal.
14 TRANSPORTATION INFORMATION
Department of Transportation (DOT) Requirements
Effective Date: 11/18/2004 ND = No Data NA = Not Applicable Replaces Sheet Dated 10/24/2000 Page 4 of 6
Catalog Number 1235B Trade Name BUTYRIC ACID, SODIUM SALT
NOT REGULATED
Proper Shipping Name
NA
Hazard Class NA
UN/NA Code
NA
Packaging Group
None
Reportable Quantity
NA
Labels Required
Marine Pollutant (49 CFR 172.101 Appendix B) No
15 REGULATORY INFORMATION
Federal Regulations
This product is listed on the Inventory of Existing Chemical Substances under the Toxic
Substances Control Act(TSCA). TSCA Section 8(b) - inventory.
NOES 1983: HZD 82158; TNF 22 (est); NIS 1; NOS 2; TNE 184 (est): TFE 101 (est)
State Regulations
Based on available information this material does not contain any components or
chemicals currently known to the State of California to cause cancer, birth defects or
reproductive harm at levels which would be subject to Proposition 65.
Reformulation, use or processing of this product may affect its composition and would
require re-evaluation
International Regulations
CANADA: Domestic Substances List / Non-Confidential.
Listed on chemical list(s) in the following countries: AUSTRALIA; JAPAN; KOREA;
PHILLIPINES
International Phrases
R- 36/37/38 Irritating to eyes, respiratory system and skin.
S- 22 Do not breathe dust.
24/25 Avoid contact with skin and eyes.
EINECS - 205-857-6
SARA TITLE III RATINGS
Immediate Delayed Fire Pressure Reactivity SARA 313
Hazard Hazard Hazard Hazard Hazard Chemical
NFPA Ratings
Health Flammability Reactivity Special Hazards
- - - -
HMIS RATINGS
Health Flammabilty Reactivity Personal Protection
Equipment
2 0 0 E
Effective Date: 11/18/2004 ND = No Data NA = Not Applicable Replaces Sheet Dated 10/24/2000 Page 5 of 6
Catalog Number 1235B Trade Name BUTYRIC ACID, SODIUM SALT
16 OTHER INFORMATION
Disclaimer
The data contained in this Material Safety Data Sheet relates only to the specific material
designated herein. It does not relate to use in combination with any other material or in any
process. Research Organics, Inc. provides the information contained herein in good faith but
make no representation as to its comprehensiveness or accuracy. Individuals receiving this
information must exercise their independent judgment in determining it appropriateness for a
particular purpose. Research Organics, Inc. makes no representations, or warranties, either
expressed or implied, of merchantability, fitness for a particular purpose with respect to the
information refers. Accordingly, Research Organics, Inc. will not be responsible for damages
resulting from the use of reliance upon this information. In no instance is any Research
Organics, Inc. product offered for drug, food, food additive or clinical use in humans.
10/24/2000
Completed On: 11/18/2004 Replaces Sheet Dated:
Completed By: Environmental and Safety Department
Effective Date: 11/18/2004 ND = No Data NA = Not Applicable Replaces Sheet Dated 10/24/2000 Page 6 of 6
Catalog Number 1235B Trade Name BUTYRIC ACID, SODIUM SALT
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