MATERIAL SAFETY DATA SHEET
1 CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
TRADE NAME TES, MOLECULAR BIOLOGY GRADE
7365-44-8
CAS NUMBER
9660T
ROI NUMBER
N-[Tris(hydroxymethyl)methyl]-2-
SYNONYMS
aminoethanesulfonic acid, Molecular Biology
Grade
MANUFACTURER/ Research Organics
4353 E 49th Street
SUPPLIER
Cleveland, Ohio
44125 USA
TELEPHONE NUMBERS - 24 HOUR EMERGENCY ASSISTANCE:
INFOTRAC 800-535-5053
TELEPHONE NUMBERS - GENERAL ASSISTANCE:
Product Information 800-321-0570
2 COMPOSITION / INFORMATION ON INGREDIENTS
Ingredient CAS Number Percentage* Exposure Limits/Health Hazards
TES, MOLECULAR BIOLOGY GRADE 7365-44-8 >99 % Particulate Not Otherwise Classified - TWA
Respirable particulate (1995) = 3 mg/m3(e)
MAY BE IRRITATING, MAY BE HARMFUL.
*Values do not reflect absolute minimums and maximums; those values may vary from time to time.
3 HAZARDS IDENTIFICATION
Emergency Overview
CAUTION!
MAY BE IRRITATING TO THE SKIN, EYES, AND UPPER RESPIRATORY TRACT.
MAY BE HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN
Potential Health Effects Skin
This material May cause skin irritation. Reddening, itching and inflammation may result.
May be absorbed through the skin.
Potential Health Effect Eyes
Direct contact may cause irritation, redness, tearing and blurred vision.
Potential Health Effects Inhalation
May cause irritation to the respiratory tract.
This material may cause injury or illness if inhaled.
Potential Health Effect Ingestion
If ingested, this material may cause irritation to the mouth, throat and gastrointestinal tract.
Effective Date: 3/3/2006 ND = No Data NA = Not Applicable Replaces Sheet Dated 5/23/2003 Page 1 of 6
Catalog Number 9660T Trade Name TES, MOLECULAR BIOLOGY GRADE
May be harmful if ingested. Exposure may cause nausea, headache and vomiting.
Special Toxic Effects
CAUTION! THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT BEEN FULLY
INVESTIGATED.
Target Organs
ND
4 FIRST AID MEASURES
Skin
Immediately flush skin with plenty of water, for at least 15 minutes, while removing contaminated clothing and
shoes. Contaminated clothing must be laundered before reuse. Get medical attention if irritation develops or
persists.
Eyes
Flush immediately with large amounts of water for at least 15 minutes. Eyelids should be held away from the
eyeball to ensure thorough rinsing.
Get medical attention if irritation persists.
Inhalation
Safely remove victim to fresh air. If not breathing, institute artificial respiration/rescue breathing. If breathing is
difficult, ensure clear airway and give oxygen.
Get medical attention.
Ingestion
If swallowed, wash out mouth with water provided person is conscious.
Never give anything by mouth to an unconscious person.
Get medical attention.
5 FIRE FIGHTING MEASURES
Hazardous Combustion Products
MAY EMIT TOXIC FUMES UNDER FIRE CONDITIONS.
Extinguishing Media
Use a water spray, dry chemical, alcohol foam, all purpose foam or carbon dioxide to extinguish fire.
Basic Fire Fighting Procedure
As in any fire, wear self-contained breathing apparatus pressure-demand, (MSHA/NIOSH approved or
equivalent) and full protective gear. Evacuate the area and fight fire from a safe distance.
Unusual Fire and Explosion Hazards
None known to manufacturer.
ND (Solid)
Flash Point Temperature
ND
Autoignition Temperature
ND
Flammability Limits in Air Lower
ND
Flammability Limits in Air Upper
6 ACCIDENTAL RELEASE MEASURES
Emergency Action
Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind. (See Personal Protection
Information Section.)
Environmental Precautions
Isolate hazard area and deny entry. Keep unnecessary people away. Take immediate steps to stop and
Effective Date: 3/3/2006 ND = No Data NA = Not Applicable Replaces Sheet Dated 5/23/2003 Page 2 of 6
Catalog Number 9660T Trade Name TES, MOLECULAR BIOLOGY GRADE
contain the spill. Caution should be exercised regarding personnel safety and exposure to the spilled material.
Spill or Leak Procedure
Vacuum or sweep up material and place in a disposal container. Clean up spills immediately under quailfied
supervision observing precautions in Protective Equipment section. Avoid clean up procedures that generate
dust or result in water pollution.
After removal, scrub the contaminated area with detergent and flush thoroughly with water. Absorb wash liquid
and place in the disposable container. Do not flush to sewer. Avoid runoff into storm sewers and ditches which
lead to waterways.
7 HANDLING AND STORAGE
Handling
Use only in a well ventilated area. Avoid contact with skin,eyes and on clothing. Empty containers may contain
material residue. Do not reuse. Do not eat, drink or smoke in areas of use or storage.
Minimize dust generation during handling and contact.
Wash hands thoroughly before eating, drinking or smoking.
Storage
Store at room temperature.
Keep containers tightly closed and upright when not in use.
Storage Hazards
Store away from oxidizers.
8 EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Contols
Local exhaust ventilation, process enclosures, and other forms of engineering controls are the preferred means
for controlling exposures.
Facilities using or storing this material must be equipped with an eyewash station and safety shower.
Eye Protection PPE
Avoid eye contact with this material. Wear chemical safety goggles.
Do not wear contact lenses when working with this substance.
Skin Protection PPE
Wash contaminated clothing separately.
Showering and changing into street clothing after work is recommended.
Avoid skin contact with this material. Use appropriate chemical protective gloves when handling.
Respiratory Protection PPE
A NIOSH/MSHA approved dust respirator should be used as a precautionary measure when airborne
contaminates may occur.
Use a positive pressure air supplied respirator if there is any potential for an uncontrolled release, exposure
levels are not known, or any other circumstance where air purifing respirators may not provide adequate
protection.
A respiratory protection program that meets OSHA 1910.134 and ANSI Z88.2 requirements must be followed
whenever workplace conditions warrant a respirators use.
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne levels below
recommended exposure limits.
9 PHYSICAL AND CHEMICAL PROPERTIES
Appearance
WHITE POWDER
ND
Boiling Point
223 - 225 C
Melting Point
ND
Freezing Point
Vapor Density ND
Effective Date: 3/3/2006 ND = No Data NA = Not Applicable Replaces Sheet Dated 5/23/2003 Page 3 of 6
Catalog Number 9660T Trade Name TES, MOLECULAR BIOLOGY GRADE
Vapor Pressure ND
ND
Specific Gravity
C6H15NO6S
Molecular Formula
229.2
Molecular Weight
1.0%; 3.5 鈥? 5.0
pH
10 STABILITY / REACTIVITY
Stability/Incompatibility
Stable under normal conditions of use.
Incompatible with strong oxidizing agents.
Decomposition Products
Combustion may produce CO, CO2, NOx and/or SOx.
Hazardous Polymerization
Will not occur.
11 TOXICOLOGICAL INFORMATION
CAUTION! THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT BEEN FULLY
INVESTIGATED. FOLLOW GOOD LABORATORY PRACTICES WHEN HANDLING.
Routes of Exposure
Inhalation, ingestion, skin and eye contact.
LD50
REGISTRY OF THE TOXIC EFFECTS OF CHEMICAL SUBSTANCES(RTECS)
RTECS # Not listed
NO ORAL LD50 IN RATS INFORMATION IS AVAILABLE.
Carcinogenicity
NOT LISTED BY IARC, NTP OR OSHA AS A CARCINOGEN
12 ECOLOGICAL INFORMATION
EcoToxicological Information
DATA NOT YET AVAILABLE.
Chemical Fate Information
DATA NOT YET AVAILABLE.
13 DISPOSAL CONSIDERATIONS
Waste Disposal
Under RCRA, it is the responsibility of the user of the product to determine, at the time of disposal, whether the
product meets RCRA criteria for hazardous waste.
If the material is determined to be a hazardous waste, the transportation, storage, treatment and disposal of this
waste material must be conducted in compliance with 40 CFR 262, 263, 264, 268 and 270. Disposal can occur
only in properly permitted facilities.
14 TRANSPORTATION INFORMATION
Department of Transportation (DOT) Requirements
NOT REGULATED
Proper Shipping Name
NA
Hazard Class NA
UN/NA Code
NA
Packaging Group
None
Reportable Quantity
NA
Labels Required
Marine Pollutant (49 CFR 172.101 Appendix B) No
15 REGULATORY INFORMATION
Effective Date: 3/3/2006 ND = No Data NA = Not Applicable Replaces Sheet Dated 5/23/2003 Page 4 of 6
Catalog Number 9660T Trade Name TES, MOLECULAR BIOLOGY GRADE
Federal Regulations
This product is listed on the Inventory of Existing Chemical Substances under the Toxic
Substances Control Act(TSCA)
State Regulations
Based on available information this material does not contain any components or
chemicals currently known to the State of California to cause cancer, birth defects or
reproductive harm at levels which would be subject to Proposition 65.
Reformulation, use or processing of this product may affect its composition and would
require re-evaluation
International Regulations
CANADA: Domestic Substances List / Non-Confidential.
International Phrases
ND Not Determined
R-
36/37/39 Wear suitable protective clothing, gloves & eye/face protection.
S-
38 In case of insufficient ventilation, wear suitable respiratory equipment.
230-906-3
EINECS -
SARA TITLE III RATINGS
Immediate Delayed Fire Pressure Reactivity
Hazard Hazard Hazard Hazard Hazard
Section 313 Supplier Notification:
If this box is checked, this product contains EPCRA 313 chemical(s) subject to the reporting
requirements of Section 313 of the Emergency Planning and Community Right-To-Know Act of 1986
(40 CFR 372). If you are unsure whether you are subject to reporting requirements or need more
information, call EPA's ECPRA Call Center at (800) 424-9346 or (703) 412-9810.
NFPA(R) Ratings
Health Flammability Reactivity Special Hazards
- - - -
HMIS(R) RATINGS
Health Flammabilty Physical Personal Protection
Hazard Equipment
1 0 0 E
NFPA is a registrated trademark of National Fire Protection Association. HMIS is a registrated trademark of National Paint and Coating Association.
16 OTHER INFORMATION
Disclaimer
Effective Date: 3/3/2006 ND = No Data NA = Not Applicable Replaces Sheet Dated 5/23/2003 Page 5 of 6
Catalog Number 9660T Trade Name TES, MOLECULAR BIOLOGY GRADE
The data contained in this Material Safety Data Sheet relates only to the specific material
designated herein. It does not relate to use in combination with any other material or in any
process. Research Organics, Inc. provides the information contained herein in good faith but
make no representation as to its comprehensiveness or accuracy. Individuals receiving this
information must exercise their independent judgment in determining it appropriateness for a
particular purpose. Research Organics, Inc. makes no representations, or warranties, either
expressed or implied, of merchantability, fitness for a particular purpose with respect to the
information refers. Accordingly, Research Organics, Inc. will not be responsible for damages
resulting from the use of reliance upon this information. In no instance is any Research
Organics, Inc. product offered for drug, food, food additive or clinical use in humans.
5/23/2003
Completed On: 3/3/2006 Replaces Sheet Dated:
Completed By: Environmental and Safety Department
Effective Date: 3/3/2006 ND = No Data NA = Not Applicable Replaces Sheet Dated 5/23/2003 Page 6 of 6
Catalog Number 9660T Trade Name TES, MOLECULAR BIOLOGY GRADE
|