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2-MERCAPTOETHANOL
Material Safety Data Sheet
Arkema Inc.
1 PRODUCT AND COMPANY IDENTIFICATION
EMERGENCY PHONE NUMBERS:
Thio and Fine Chemicals
Chemtrec: (800) 424-9300 (24hrs) or (703) 527-3887
Arkema Inc.
Medical: Rocky Mountain Poison Control Center
2000 Market Street
(866) 767-5089 (24Hrs)
Philadelphia, PA 19103
Information Telephone Numbers Phone Number Available Hrs
Customer Service 1-800-628-4453 8:30 to 5:30 EST
Product Name 2-MERCAPTOETHANOL
Product Synonym(s) Thioglycol
Chemical Family
Chemical Formula
Chemical Name 2-Mercaptoethanol
EPA Reg Num
Product Use
2 COMPOSITION / INFORMATION ON INGREDIENTS
Ingredient Name CAS RegistryNumber Typical % OSHA
Water 7732-18-5 0.5% N
2-Mercaptoethanol 60-24-2 99% Y
The substance(s) marked with a "Y" in the OSHA column, are identified as hazardous chemicals according to the
criteria of the OSHA Hazard Communication Standard (29 CFR 1910.1200)
This material is classified as hazardous under Federal OSHA regulation.
The components of this product are all on the TSCA Inventory list.
3 HAZARDS IDENTIFICATION
Emergency Overview
Colorless to light yellow liquid
DANGER!
MAY BE FATAL IF ABSORBED THROUGH SKIN.
HARMFUL IF SWALLOWED.
CAUSES EYE IRRITATION.
CAUSES SEVERE SKIN BURNS.
CAUSES RESPIRATORY TRACT IRRITATION.
MAY CAUSE ALLERGIC SKIN REACTION.
MAY CAUSE NAUSEA, HEADACHE OR DIZZINESS.
Potential Health Effects
Inhalation and skin contact are expected to be the primary routes of occupational exposure to this material. Based on
single exposure animal tests, it is considered to be moderately toxic if swallowed, highly toxic if absorbed through skin,
slightly toxic if inhaled, and severely irritating to eyes and skin. This material has a strong objectionable odor and may
cause nausea, headache, or dizziness. High vapor concentrations may be irritating to the eyes and respiratory tract,
and may result in central nervous system (CNS) effects such as headache, dizziness, nausea, drowsiness and, in
Product Code: 000919 Page 1
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2-MERCAPTOETHANOL
Material Safety Data Sheet
Arkema Inc.
severe exposures, loss of consciousness and death. Repeated or prolonged may cause an allergic skin reaction.
4 FIRST AID MEASURES
IF IN EYES, immediately flush with plenty of water for at least 15 minutes. Get medical attention immediately.
IF ON SKIN, immediately flush with plenty of water. Remove contaminated clothing and shoes. Get medical
attention. Wash clothing before reuse. Destroy contaminated shoes.
IF SWALLOWED, do NOT induce vomiting. Give water to drink. Get medical attention immediately. NEVER
GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS PERSON.
IF INHALED, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical attention.
5 FIRE FIGHTING MEASURES
Fire and Explosive Properties
Auto-Ignition Temperature NE
Flash Point 73 C (163 F) Flash Point Method PMCC
Flammable Limits- Upper 18% in volume
2.3% in volume
Lower
Extinguishing Media
Use water spray, carbon dioxide, foam or dry chemical.
Fire Fighting Instructions
Fire fighters and others who may be exposed to products of combustion should wear full fire fighting turn out
gear (full Bunker Gear) and self-contained breathing apparatus (pressure demand NIOSH approved or
equivalent). Fire fighting equipment should be thoroughly decontaminated after use.
Fire and Explosion Hazards
When burned, the following hazardous products of combustion can occur:
Sulfur oxides
Oxides of carbon
and Hydrogen sulfide
6 ACCIDENTAL RELEASE MEASURES
In Case of Spill or Leak
Contain spill. Stop leak at source if this can be done safely. Ventilate area. Nonessential personnel should
leave the area until cleanup is completed. Pump liquid into DOT-approved drums for disposal. Absorb
remaining liquid onto inert absorbent and place in DOT approved drums for disposal. Wash area with water.
Keep concentrate and wash water from entering sewers or waterways. Consult a regulatory specialist to
determine appropriate state or local reporting requirements, for assistance in waste characterization and/or
hazardous waste disposal and other requirements listed in pertinent environmental permits.
7 HANDLING AND STORAGE
Handling
Do not taste or swallow.
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Material Safety Data Sheet
Arkema Inc.
7 HANDLING AND STORAGE
Do not breathe vapor.
Do not get in eyes, on skin or on clothing.
Wash thoroughly after handling.
Keep container closed.
Use only with adequate ventilation.
Keep away from heat, sparks and flames.
Storage
Store in a cool, dry place. Avoid excessive heat. Store out of direct sunlight in a cool, well-ventilated place.
8 EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls
Investigate engineering techniques to reduce exposures below airborne exposure limits. Provide ventilation
if necessary to control exposure levels below airborne exposure limits (see below). If practical, use local
mechanical exhaust ventilation at sources of air contamination such as open process equipment. Consult
ACGIH ventilation manual or NFPA Standard 91 for design of exhaust systems.
Eye / Face Protection
Where there is potential for eye contact, wear a face shield, chemical goggles, and have eye flushing
equipment immediately available.
Skin Protection
Gloves should be worn when handling this material. Wear chemical goggles, a face shield, and chemical
resistant clothing such as a rubber apron when splashing may occur. Rinse immediately if skin is
contaminated. Remove contaminated clothing promptly and wash before reuse. Clean protective equipment
before reuse. Provide a safety shower at any location where skin contact can occur. Wash skin thoroughly
after handling.
Respiratory Protection
Avoid breathing vapor or mist. When airborne exposure limits are exceeded (see below), use NIOSH
approved respiratory protection equipment appropriate to the material and/or its components. Full facepiece
equipment is recommended and, if used, replaces need for face shield and chemical goggles. Consult
respirator manufacturer to determine appropriate type equipment for given application. Observe respirator
use limitations specified by NIOSH or the manufacturer. For emergency and other conditions where
exposure limit may be significantly exceeded, use an approved full face positive-pressure, self-contained
breathing apparatus or positive-pressure airline with auxiliary self-contained air supply. Respiratory
protection programs must comply with 29 CFR 搂 1910.134.
Airborne Exposure Guidelines for Ingredients
Exposure Limit Value
2-Mercaptoethanol
WEEL TWA - 0.2 ppm 0.6 mg/m3
-Only those components with exposure limits are printed in this section.
-Skin contact limits designated with a "Y" above have skin contact effect. Air sampling alone is insufficient to accurately quantitate
exposure. Measures to prevent significant cutaneous absorption may be required.
-ACGIH Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic reactions.
-WEEL-AIHA Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic skin reactions.
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Revision: 9 Issued: 30 DEC 2005 of 6
2-MERCAPTOETHANOL
Material Safety Data Sheet
Arkema Inc.
9 PHYSICAL AND CHEMICAL PROPERTIES
Colorless to light yellow liquid
Appearance/Odor
pH NE
Specific Gravity NE
Vapor Pressure 1.33 hPa (mbar) (20 C)
Vapor Density 1116.8 kg/m3 (20 C)
Melting Point NA
Freezing Point NE
Boiling Point 157-158 C
Solubility In Water Soluble
Molecular Weight 78.13 g
Other Physical Data Odor threshold: 0.38 - 2.04 mg/m3
10 STABILITY AND REACTIVITY
Stability
This material is chemically stable under normal and anticipated storage and handling conditions.
Incompatibility
Avoid contact with strong oxidizing agents and strong bases.
Hazardous Decomposition Products
Hydrogen sulphide
Oxides of sulphur
Carbon oxides
11 TOXICOLOGICAL INFORMATION
Toxicological Information
Data on this material and/or its components are summarized below.
Single exposure (acute) studies indicate:
Oral - Moderately Toxic to Rats (LD50 241-345 mg/kg)
Dermal - Highly Toxic to Rabbits (LD50 150-200 mg/kg)
Inhalation - Slightly Toxic to Rats (4-hr LC50 625 ppm)
Eye Irritation - Severely Irritating to Rabbits
Skin Irritation - Severely Irritating to Rabbits
Skin allergy was observed in guinea pigs following repeated exposure. No birth defects were observed in the
offspring of rats exposed orally during pregnancy, although slight adverse effects on the fetus were observed.
No genetic changes were observed in tests using bacteria or human cells. Both positive and negative results
were observed in tests using animal cells and animals.
12 ECOLOGICAL INFORMATION
Ecotoxicological Information
Data on this material and/or its components are summarized below.
2-Mercaptoethanol
This material is slightly toxic to golden orfe (96-hr LC50 46-100 mg/kg) and algae (72-hr IC50 12 mg/l). It is
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Material Safety Data Sheet
Arkema Inc.
12 ECOLOGICAL INFORMATION
highly toxic to Daphnia magna (48-hr EC50 0.89 mg/l) and practically non-toxic to guppies (24-hr LC50 187
mg/l), bacteria (17-hr EC50 125 mg/l) and plants (3-hr EC50 for inhibition of germinations is 187-202 mg/l).
Chemical Fate Information
Data on this material and/or its components are summarized below.
2-Mercaptoethanol
This material is not readily biodegradable (<20% after 28-days) and is not bioaccumulable (log Pow -0.3). It is
slightly adsorptive in soils and sediments (log Koc 1.2) and is degraded by OH radicals in air (half-life 8.7-
hours).
13 DISPOSAL CONSIDERATIONS
Waste Disposal
Incineration is the recommended method for disposal observing all local, state and federal regulations. Note:
Chemical additions to, processing of, or otherwise altering this material may make this waste management
information incomplete, inaccurate, or otherwise inappropriate. Furthermore, state and local waste disposal
requirements may be more restrictive or otherwise different from federal laws and regulations. Take
appropriate measures to prevent release to the environment.
14 TRANSPORT INFORMATION
DOT Name Thioglycol
DOT Technical Name
DOT Hazard Class 6.1
UN Number 2966
DOT Packing Group PG ll
RQ
Marine Pollutant yes
Primary Hazard Label: TOXIC
DOT Special Information
15 REGULATORY INFORMATION
Hazard Categories Under Criteria of SARA Title III Rules (40 CFR Part 370)
Immediate (Acute) Health Y Fire N
Reactive
Delayed (Chronic) Health N N
Sudden Release of Pressure N
The components of this product are all on the TSCA Inventory list.
Ingredient Related Regulatory Information:
CERCLA RQ SARA TPQ
SARA Reportable Quantities
Water NE
2-Mercaptoethanol NE NE
Massachusetts Right to Know
This product does contain the following chemicals(s), as indicated below, currently on the Massachusetts Right to Know Substance
List.
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2-MERCAPTOETHANOL
Material Safety Data Sheet
Arkema Inc.
Massachusetts Right to Know
This product does contain the following chemicals(s), as indicated below, currently on the Massachusetts Right to Know Substance
List.
2-Mercaptoethanol
Pennsylvania Right to Know
This product does contain the following chemical(s), as indicated below, currently on the Pennsylvania Hazardous Substance List.
2-Mercaptoethanol
16 OTHER INFORMATION
Revision Information
Revision Number 9
30 DEC 2005
Revision Date
Supercedes Revision Dated 19-OCT-2004
Revision Summary
Revised Section 14
Key
NE= Not Established NA= Not Applicable (R) = Registered Trademark
Arkema Inc. believes that the information and recommendations contained herein (including data and
statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR
PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR
IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided
herein relates only to the specific product designated and may not be valid where such product is used in
combination with any other materials or in any process. Further, since the conditions and methods of use are
beyond the control of Arkema Inc., Arkema Inc. expressly disclaims any and all liability as to any results
obtained or arising from any use of the product or reliance on such information.
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