MATERIAL SAFETY DATA SHEET
MSDS DATE:07/31/07
SECTION 1: PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME: THIOSEMICARBAZIDE
SYNONYMS: HYDRAZINECARBOTHIOAMIDE, N-AMINOTHIOUREA
PRODUCT CODES: 22000
MANUFACTURER: ELECTRON MICROSCOPY SCIENCES
DIVISION: 1560 INDUSTRY ROAD/P.O. BOX 550
ADDRESS: HATFIELD, PA 19440
EMERGENCY PHONE: 215-412-8400
CHEMTREC PHONE: 800-424 -4300
FAX PHONE: 215-412-8450
CHEMICAL NAME: THIOSEMICARBAZIDE
CHEMICAL FAMILY: N/A
SECTION 2: COMPOSITION/INFORMATION ON INGREDIENTS
INGREDIENT:
THIOSEMICARBAZIDE
CAS NO. % WT % VOL SARA 313 REPORTABLE
79-19-6 N/A 99
mg/m3
ppm
OSHA PEL-TWA: N/A N/A
OSHA PEL STEL : N/A N/A
OSHA PEL CEILING: N/A N/A
ACGIH TLV-TWA: N/A N/A
ACGIH TLV STEL: N/A N/A
ACGIH TLV CEILING: N/A N/A
SECTION 3: HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW:
ROUTES OF ENTRY: SKIN, EYES, INHALATION, INGESTION
POTENTIAL HEALTH EFFECTS
EYES: MAY CAUSE EYE IRRITATION
SKIN: MAY CAUSE SKIN IRRITATION. MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN IRRITATION
INGESTION: MAY BE FATAL IF SWALLOWED. MAY CAUSE GASTROINTESTINAL IRRITATION WITH NAUSEA, VOMITING AND
DIARRHEA.
INHALATION: MAY CUASE RESPIRATORY TRACT IRRITATION. MAY BE HARMFUL IF INHALED
ACUTE HEALTH HAZARDS: N/A
CHRONIC HEALTH HAZARDS: N/A
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE: N/A
CARCINOGENICITY
OSHA: N/A ACGIH: 0 NTP: 0 IARC: 0
PAGE 1 OF 6
MATERIAL SAFETY DATA SHEET
MSDS DATE:07/31/07
OTHER: CA PROP 65: 0
SECTION 4: FIRST AID MEASURES
EYES: FLUSH WITH WATER FOR 15 MINUTES OCCASIONALY LIFTING THE UPPER AND LOWER EYELIDS. IF IRRITATION
OCCURS. SEEK MEDICAL ATTENTION
SKIN: WASH WITH PLENTY OF SOAP AND WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING
AND SHOES. IF IRRITATION OCCURS. SEEK MEDICAL ATTENTION. WASH CLOTHING BEFORE REUSE
INGESTION: NEVER GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS PERSON. SPEED IS ESSENTIAL. A DOCTOR MUST BE
NOTIFIED AT ONCE. DO NOT INDUCE VOMITING. IF CONSCIOUS AND ALERT, RINSE MOUTH AND DRINK 2-4 CUPFULS OF MILK
OR WATER
INHALATION: GET MEDICAL AID IMMEDIATELY. REMOVE FROM EXPOSURE AND MOVE TO FRESH AIR IMMEDIATELY. IF
BREATHING IS DIFFICULT, GIVE OXYGEN. DO NOT USE MOUTH TO MOUTH RESUSCITATION. IF BREATHING HAS CEASED APPLY
ARTIFICIAL RESPIRATION USING OXYGEN AND A SUITABLE MECHANICAL DEVICE SUCH AS A BAG AND A MASK.
NOTES TO PHYSICIANS OR FIRST AID PROVIDERS: N/A
SECTION 5: FIRE-FIGHTING MEASURES
FLAMMABLE LIMITS IN AIR, UPPER: N/A
(% BY VOLUME) LOWER: N/A
FLASH POINT: N/A
F: N/A
C: N/A
METHOD USED: N/A
AUTOIGNITION TEMPERATURE: N/A
F: N/A
C: N/A
NFPA HAZARD CLASSIFICATION
HEALTH: 3 FLAMMABILITY: 0 REACTIVITY: N/A
OTHER: N/A
HMIS HAZARD CLASSIFICATION
HEALTH: N/A FLAMMABILITY: N/A REACTIVITY: N/A
PROTECTION: N/A
EXTINGUISHING MEDIA: USE WATER SPRAY, DRY CHEMICAL, CARBON DIOXIDE, OR CHEMICAL FOAM
SPECIAL FIRE FIGHTING PROCEDURES: N/A
UNUSUAL FIRE AND EXPLOSION HAZARDS: N/A
HAZARDOUS DECOMPOSITION PRODUCTS: N/A
SECTION 6: ACCIDENTAL RELEASE MEASURES
ACCIDENTAL RELEASE MEASURES: VACUUM OR SWEEP UP MATERIAL AND PLACE INTO A SUITABLE DISPOSAL CONTAINER.
CLEAN UP SPILLS IMMEDIATLEY, OBSERVING PRECAUTIONS IN THE PROTECTIVE EQUPIMENT SECTION. AVOID GENERATING
DUSTY CONDITIONS. PROVIDE VENTILATION.
PAGE 2 OF 6
MATERIAL SAFETY DATA SHEET
MSDS DATE:07/31/07
SECTION 7: HANDLING AND STORAGE
HANDLING AND STORAGE:WASH THOROUGHLY AFTER HANDLING. MINIMIZE DUST GENERATION AND ACCUMULATION. AVOID
CONTACT WITH EYES, SKIN, AND CLOTHING. DO NOT BREATHE DUST, MIST PR VAPOR. KEEP CONTAINER TIGHTLY CLOSED.
AVOID INGESTION AND INHALATION. USE ONLY IN A CHEMICAL FUME HOOD.
STORE IN A COOL, DRY, WELL VENTILATED AREA AWAY FROM INCOMPATIBLE SUBSTANCES- POISON ROOM LOCKED. KEEP
CONTAINERS TIGHTLY CLOSED.
OTHER PRECAUTIONS:
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
ENGINEERING CONTROLS: FACILITIES STORING OR UTILIZING THIS MATERIAL SHOULD BE EQUIPPED WITH AN EYEWASH
FACILITY AND SAFETY SHOWER. USE ADEQUATE VENTILATION TO KEEP AIRBORNE CONCENTRATIONS LOW
VENTILATION: N/A
RESPIRATORY PROTECTION: FOLLOW THE OSHA RESPIRATOR REGULATIONS FOUND IN 29 CFR 1910.134 OR EUROPEAN
STANDARD EN 149. USE A NIOSH/MSHA OR ERUOPEAN STANDARD EN 149 APPROVED RESPIRATOR IF EXPOSURE LIMITS ARE
EXCEEDED OR IF IRRITATION OR OTHER SYMPTOMS ARE EXPIRIENCED.
EYE PROTECTION: WEAR APPROPRIATE PROTECTIVE EYEGLASSES OR CHEMICAL SAFETY GOGGLES AS DESCRIBED BY
OSHA鈥橲 EYE AND FACE PROTECTION REGULATIONS IN 29 CFR 1910.133 OR EUROPEAN STANDARD EN166
SKIN PROTECTION: WEAR APPROPRIATE PROTECTIVE GLOVES TO PREVENT SKIN EXPOSURE.
OTHER PROTECTIVE CLOTHING OR EQUIPMENT: WEAR APPROPRIATE PROTECTIVE CLOTHING TO PREVENT SKIN EXPOSURE.
WORK HYGIENIC PRACTICES: WASH THOROUGHLY AFTER HANDLING. WASH CLOTHING BEFORE REUSE.
EXPOSURE GUIDELINES:
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE: WHITE TO YELLOW
ODOR: ODORLESS
PHYSICAL STATE: POWDER
pH AS SUPPLIED: N/A
pH (Other): N/A
BOILING POINT: N/A
F: N/A
C: N/A
MELTING POINT:
F: N/A
C: 175-180 DEG
FREEZING POINT: N/A
F: N/A
C: N/A
VAPOR PRESSURE (mmHg): N/A
@
F: N/A
C: N/A
VAPOR DENSITY (AIR = 1): N/A
@
F: N/A
C: N/A
@
F: N/A
C: N/A
EVAPORATION RATE: N/A
PAGE 3 OF 6
MATERIAL SAFETY DATA SHEET
MSDS DATE:07/31/07
BASIS (=1): N/A
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES (con鈥檛)
SOLUBILITY IN WATER: SOLUBLE
PERCENT SOLIDS BY WEIGHT: N/A
PERCENT VOLATILE: N/A
BY WT/ BY VOL @
F: N/A
C: N/A
VOLATILE ORGANIC COMPOUNDS (VOC): N/A
WITH WATER: N/A LBS/GAL
WITHOUT WATER: N/A LBS/GAL
MOLECULAR WEIGHT: 91.13
VISCOSITY: N/A
@
F: N/A
C: N/A
SECTION 10: STABILITY AND REACTIVITY
STABILITY: N/A
CONDITIONS TO AVOID (STABILITY): TEMPERATURES ABOVE 150 DEG C
INCOMPATIBILITY (MATERIAL TO AVOID): STRONG OXIDIZING AGENTS, STRONG ACIDS, STRONG BASES.
HAZARDOUS DECOMPOSITION OR BY-PRODUCTS: NITROGEN OXIDES, CARBON MONOXIDE, OXIDES OF SULFUR, CARBON
DIOXIDE.
HAZARDOUS POLYMERIZATION: N/A
CONDITIONS TO AVOID (POLYMERIZATION): N/A
SECTION 11: TOXICOLOGICAL INFORMATION
TOXICOLOGICAL INFORMATION:
LD50/LC50:
RTECHS: CAS # 79-19-6: ORAL, RABBIT: LD50= 13 MG/KG
ORAL, RAT: LD50= 9160 UG/KG; SKIN RABBIT: LD50= 2200 MG/KG
SECTION 12: ECOLOGICAL INFORMATION
ECOLOGICAL INFORMATION: N/A
SECTION 13: DISPOSAL CONSIDERATIONS
WASTE DISPOSAL METHOD: COMPLY WITH FEDERAL, STATE, LOCAL REGULATIONS.
RCRA HAZARD CLASS: N/A
PAGE 4 OF 6
MATERIAL SAFETY DATA SHEET
MSDS DATE:07/31/07
SECTION 13: DISPOSAL CONSIDERATIONS (con鈥檛)
CHEMICAL WASTE GENERATORS MUST DETERMINE WHETHER A DISCARDED CHEMICAL IS CLASSIFIED AS A HAZARDOUS
WASTE. US EPA GUIDELINES FOR THE CLASSIFIED AS A HAZARDOUS WASTE. 40 CFR PARTS 261.3 ADDITIONALLY, WASTE
GENERATORS MUST CONSULT STATE AND LOCAL HAZARDOUS WASTE REGULATIONS TO ENSURE COMPLETE AND ACCURATE
CLASSIFICATION.
RCRA P- SERIES: WASTE NUMBER P116.
SECTION 14: TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION
PROPER SHIPPING NAME: TOXIC SOLIDS, ORGANIC, N.O.S.
HAZARD CLASS: 6.1
ID NUMBER: UN2811
PACKING GROUP: II
LABEL STATEMENT:N /A
WATER TRANSPORTATION
PROPER SHIPPING NAME:
HAZARD CLASS: SAME
ID NUMBER:
PACKING GROUP:
LABEL STATEMENTS:
AIR TRANSPORTATION
PROPER SHIPPING NAME:
HAZARD CLASS: SAME
ID NUMBER:
PACKING GROUP:
LABEL STATEMENTS:
OTHER AGENCIES: N/A
SECTION 15: REGULATORY INFORMATION
U.S. FEDERAL REGULATIONS
TSCA (TOXIC SUBSTANCE CONTROL ACT):
HEALTH AND SAFETY REPORTING LIST: NONE OF THE CHEMICALS ARE ON THE HEALTH AND SAFETY REPORTING
LIST.
CHEMICAL TEST RULES: NONE OF THE CHEMICALS IN THIS PRODUCT ARE UNDER A CHEMICAL TEST RULE
SECTION 12b: NONE OF THE CHEMICALS ARE LISTED UNDER TSCA SECTION 12b
TSCA SIGNIFICANT NEW USE RULE: NONE OF THE CHEMICALS IN THIS MATERIAL HAVE A SNUR UNDER TSCA.
CERCLA (COMPREHENSIVE RESPONSE COMPENSATION, AND LIABILITY ACT):
CERCLA HAZARDOUS SUBSTANCES AND CORRESPONDING RQs: 100LB FINAL RQ; 45.4 KG FINAL RQ
SARA TITLE III (SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT): SARA SECTION 302 EXTREMELY HAZARDOUS
SUBSTANCES: 100 LB LOWER THRESHOLD TPQ; 10000 LB UPPER THRESHOLD TPQ
311/312 HAZARD CATEGORIES: N/A
313 REPORTABLE INGREDIENTS: THIS MATERIAL CONTAINS THIOSEMICARBAZIDE, WHICH IS SUBJECT TO THE REPORTING
REQUIREMENTS OF SECTION 313 OF SARA TITLE III AND 40 CFR PART 372
STATE REGULATIONS: THIOSEMICARBAZIDE CAN BE FOUND ON THE FOLLOWING STATE RIGHT TO KNOW LISTS: NEW JERSEY,
PENNSYLVANIA, MASSACHUSETTS.
CALIFORNIA PROP 65: CALIFORNIA NO SIGNIFICANT RISK LEVEL: NONE OF THE CHEMICALS IN THIS PRODUCT ARE LISTED.
INTERNATIONAL REGULATIONS:EUROPEAN LABELING IN ACCORDANCE WITH EC DIRECTIVES
CANADA: IS LISTED ON CANADA鈥橲 DSL LIST
CANADIAN HWMIS CLASSIFICATIONS: D1A
PAGE 5 OF 6
MATERIAL SAFETY DATA SHEET
MSDS DATE:07/31/07
THIS PRODUCT HAS BEEN CLASSIFFIED IN ACCORDANCE WITH THE HAZARD CRITERIA OF THE CONTROLLED PRODUCTS
REGULATIONS AND THE MSDS CONTAINS ALL OF THE LISTED INFORMATION REQUIRED BY THOSE REGULATIONS
SECTION 16: OTHER INFORMATION
OTHER INFORMATION: N/A
PREPARATION INFORMATION: N/A
DISCLAIMER: IN COMPLIANCE WITH THE OSHA HAZARD COMMUNICATION STANDARD, 2.9 C.F.R
1910. 1200, WE ARE PROVIDING YOU WITH A MSDS FOR THE HAZARDOUS MATERIAL YOU ARE
PURCHASING.
IT IS YOUR RESPONSIBILITY TO EDUCATE YOUR EMPLOYEES ON THE SAFE USE OF THE HAZARDOUS
MATERIAL.
ELECTRON MICROSCOPY SCIENCES MAKES NO PRESENTATION AS TO THE ACCURACY OF THE
INFORMATION IN THE MSDS. THE INFORMATION IS BELIEVED TO BE CORRECT; HOWEVER, YOU
(THE CUSTOMER), SHOULD PERFORM YOUR OWN INVESTIGATION AND INDEPENDENT
VERIFICATION. IF YOU RESELL THE PRODUCT, YOU ARE RESPONSIBLE TO FORWARD THE
INFORMATION IN THE MSDS TO YOUR CUSTOMER.
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