EMS CATALOG NO: 22150
EMS PRODUCT: TRICRESYL PHOSPHATE
DATE: 12/30/01
PAGE NUMBER: One of 10
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
321 MORRIS ROAD
P.O. BOX 251
FORT WASHINGTON, PA 19034 24 HOUR EMERGENCY PHONE NUMBER
(215) 646-1566 CHEMTREC: (800) 424-9300
_________________________________________________________________
FOR PRODUCT AND SALES INFORMATION
_________________________________________________________________
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
_________________________________________________________________
PRODUCT IDENTIFICATION
_________________________________________________________________
Tricresyl Phosphate
PRODUCT NAME:
SYNONYM: Tritolyl Phosphate
CHEMICAL FORMULA: C21H21O4P
CHEMICAL FAMILY: Not available.
CAS# 1330-78-5
_________________________________________________________________
COMPOSITION AND INFORMATION ON INGREDIENTS
_________________________________________________________________
NAME: Tricresyl phosphate
1
CAS#: 1330-78-5
% BY WEIGHT: 100
TWA (mg/m3): 0.1
TOXICOLOGICAL DATA ON INGREDIENTS:
ORAL (LD50): Acute 3000 mg/kg (Rat). 3900 mg/kg (Mouse).
DERMAL (LD50): Acute: 1701 mg/kg (Rabbit). 1500 mg/kg (Cat).
VAPOR (LC50): Acute: 5000 ppm (Rat). (4 hour(s)).
_________________________________________________________________
HAZARDS IDENTIFICATION
_________________________________________________________________
POTENTIAL ACUTE HEALTH EFFECTS:
Very dangerous in case of ingestion. Slightly dangerous in
case of skin contact (permeator), of eye contact (irritant),
of inhalation. Very slightly to slightly dangerous in case
of skin contact (irritant). Severe over-exposure can result
in death. Can be fatal if inhaled or ingested. This
product may irritate eyes and skin upon contact.
POTENTIAL CHRONIC HEALTH EFFECTS:
Very dangerous in case of ingestion.
Slightly dangerous to dangerous in case of skin contact
(permeator), of eye contact (irritant), of inhalation. Very
slightly to slightly dangerous in case of skin contact
(irritant).
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
The substance is toxic to the nervous system.
TOXICITY OF THE PRODUCT TO THE REPRODUCTIVE SYSTEM:Not
available.
Repeated or prolonged exposure to the substance can produce
target organs damage. Repeated exposure to an highly toxic
material may produce general deterioration of health by an
accumulation in one or many organs.
2
_________________________________________________________________
FIRST AID MEASURES
_________________________________________________________________
EYE CONTACT:
Check for and remove any contact lenses. IMMEDIATELY flush
eyes with running water for at least 15 minutes, keeping
eyelids open. COLD water may be used. DO NOT use an eye
ointment. Seek medical attention.
SKIN CONTACT:
If the chemical got onto the clothed portion of the body,
remove the contaminated clothes as quickly as possible,
protecting your own hands and body. Place the victim under
a deluge shower. If the chemical touches the victim's
exposed skin, such as the hands: Gently and thoroughly wash
the contaminated skin with running water and non-abrasive
soap. Be particularly careful to clean folds, crevices,
creases and groin. Cover the irritated skin with an
emollient. If irritation persists, seek medical attention.
Wash contaminated clothing before reusing.
SERIOUS SKIN CONTACT:
Wash with a disinfectant soap and cover the contaminated
skin with an anti-bacterial cream. Seek immediate medical
attention.
INHALATION:
Allow the victim to rest in a well ventilated area. Seek
immediate medical attention.
SERIOUS INHALATION:
Evacuate the victim to a safe area as soon as possible.
Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If
the victim is not breathing, perform mouth-to-mouth
resuscitation. WARNING: It may be dangerous to the person
providing aid to give mouth-to-mouth resuscitation when the
inhaled material is toxic, infectious or corrosive. Seek
immediate medical attention.
INGESTION:
Remove dentures if any. Watch for an obstruction in the
victim's mouth. Remove if possible what is causing the
obstruction but do not force fingers or a hard object
3
between the victim's teeth. Have conscious person drink
several glasses of water or milk. INDUCE VOMITING by
sticking finger in throat. Seek immediate medical
attention.
SERIOUS INGESTION:
Examine the lips and mouth to ascertain whether the tissues
are damaged. A possible indication that the material was
ingested; the absence of such signs, however is not
conclusive. Remove dentures if any. Watch for an
obstruction in the victim's mouth. Remove possible what
if
is causing the obstruction but do not force fingers or a
hard object between the victim's teeth. If a soft pad can
be inserted between the victim's teeth, it will protect the
tongue from being bitten A badly bleeding tongue immensely
complicates the patient's problems. Have conscious person
drink several glasses of water or milk. INDUCE VOMITING by
sticking finger in throat. Lower the head so that the vomit
will not reenter the mouth and throat. If convulsions
occur, do not restrain the victim, but do remove objects
with which he (she) might injure himself (herself) or orient
with victim to prevent him (her) from striking fixed heavy
objects. If the convulsions cease, turn the victim on the
side or face down so that any fluid in the mouth will
drain. Seek immediate medical attention.
________________________________________________________________
FIRE AND EXPLOSION DATA
_________________________________________________________________
FLAMMABILITY OF THE PRODUCT: Combustible.
AUTO-IGNITION TEMPERATURE: 410oC (770oF)
FLASH POINTS: Open Cup: 225oC (437oF)
FLAMMABLE LIMITS: Lower: 0.4%
PRODUCTS OF COMBUSTION:These products are carbon oxides (CO, CO2)
FIRE HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: No specific
information is in our database regarding the flammability of
this product in presence of various materials.
EXPLOSION HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES:
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF
MECHANICAL
IMPACT: Not available.
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF STATIC
DISCHARGE: Not available.
No specific information is available in our database
regarding the product's risks of explosion in the
4
presence of various materials.
FIRE FIGHTING MEDIA AND INSTRUCTIONS:
SMALL FIRE: Use DRY chemicals, CO2, water spray or foam.
LARGE FIRE: Use water spray,, fog or foam. DO NOT use water jet.
SPECIAL REMARKS ON FIRE HAZARDS: No additional remark.
SPECIAL REMARKS ON EXPLOSION HAZARDS: No additional remark.
_________________________________________________________________
ACCIDENTAL RELEASE MEASURES
_________________________________________________________________
SMALL SPILL:
Absorb with an inert material and put the spilled material
in an appropriate waste disposal.
LARGE SPILL:
Combustible material. Poisonous liquid.
Keep away from heat. Keep away from sources of ignition.
Stop leak if without risk. DO NOT get water inside
container. DO NOT touch spilled material. Use water spray
to reduce vapors. Prevent entry into sewers, basements or
confined areas; dike if needed. Eliminate all sources of
ignition. Call for assistance on disposal.
_________________________________________________________________
HANDLING AND STORAGE
_________________________________________________________________
PRECAUTIONS:
Keep locked up. keep away from heat. Keep away from
sources of ignition. Empty containers pose a fire risk,
evaporate the residue under a fume hood. Ground all
equipment containing material. DO NOT ingest. Do not
breathe gas, fumes, vapor or spray. Water suitable
protective clothing. In case of insufficient ventilation,
wear suitable respiratory equipment. If
ingested, seek medical advice immediately and show the
container or the label. Avoid contact with skin and eyes.
STORAGE:
Keep container dry. Keep in a cool place. Ground all
equipment containing material. Keep container tightly
closed. Keep in a cool, well-ventilated place. Highly
toxic or infectious materials should be stored in a separate
locked storage cabinet or room.
5
________________________________________________________________
EXPOSURE CONTROLS/PERSONAL PROTECTION
_________________________________________________________________
ENGINEERING CONTROLS:
Provide exhaust ventilation or other engineering controls to
keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash
station and safety shower is proximal to the work-station.
PERSONAL PROTECTIONS:
Splash goggles. Lab coat. Vapor respirator. Be sure to
use a MSHA/NIOSH approved respirator or equivalent. Gloves
(disposable, vinyl). Wear appropriate respirator when
ventilation is inadequate.
PERSONAL PROTECTION IN CASE OF A LARGE SPILL:
Splash goggles. Lab coat. Vapor respirator. Boots. Gloves.
A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing
might not be sufficient; consult a specialist BEFORE
handling this product.
EXPOSURE LIMITS:
TWA: 0.1 (mg/m3) from ACGIH
Consult local authorities for acceptable exposure limits.
_________________________________________________________________
PHYSICAL AND CHEMICAL PROPERTIES
_________________________________________________________________
PHYSICAL STATE AND APPEARANCE: Liquid.
ODOR: Not available.
TASTE: Not available.
COLOR: Not available.
MOLECULAR WEIGHT: 368.36
pH (1% SOLN/WATER): Not available.
BOILING POINT: 420oC (788oF)
MELTING POINT: -33oC (-27.4oF)
CRITICAL TEMPERATURE: Not available.
SPECIFIC GRAVITY: 1.16 (Water=1)
VAPOR PRESSURE: Not available.
VAPOR DENSITY: 12.7 (Air=1)
VOLATILITY: Not available.
6
ODOR THRESHOLD: Not available.
WATER/OIL DIST. COEFF.: Not available.
IONICITY (IN WATER): Not available.
DISPERSION PROPERTIES: Not available.
SOLUBILITY: Very slightly soluble in cold water.
_________________________________________________________________
STABILITY AND REACTIVITY DATA
_________________________________________________________________
STABILITY: The product is stable.
INSTABILITY TEMPERATURE: Not available.
CONDITIONS OF INSTABILITY: No additional remark.
INCOMPATIBILITY WITH VARIOUS SUBSTANCES: No specific information
is available in our database regarding the reactivity of
this material in presence of various other materials.
CORROSIVITY: Non-corrosive in presence of glass.
SPECIAL REMARKS ON REACTIVITY:No additional remark.
SPECIAL REMARKS ON CORROSIVITY:No additional remark.
POLYMERIZATION: No.
_________________________________________________________________
TOXICOLOGICAL INFORMATION
_________________________________________________________________
ROUTES OF ENTRY: Ingestion. Skin contact. Inhalation.
TOXICITY TO ANIMALS:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON
THE BASIS OF A 4-HOUR EXPOSURE.
ACUTE ORAL TOXICITY (LD50): 3000 mg/kg (Rat).
ACUTE DERMAL TOXICITY (LD50): 1500 mg/kg (Cat).
ACUTE TOXICITY OF THE VAPOR (LC50): 5000 ppm (Rat).
CHRONIC EFFECTS ON HUMANS:
The substance is toxic to the nervous system.
TOXICITY OF THE PRODUCT TO THE REPRODUCTIVE SYSTEM: Not
available.
OTHER TOXIC EFFECTS ON HUMANS:
Very dangerous in case of ingestion. Slightly dangerous in
case of dangerous in case of skin contact (permeator), of
eye contact (irritant), of inhalation. Very slightly to
slightly dangerous in case of skin contact (irritant).
SPECIAL REMARKS ON TOXICITY TO ANIMALS: No additional remark.
SPECIAL REMARKS ON CHRONIC EFFECTS ON HUMANS: No additional
remark.
SPECIAL REMARKS ON OTHER TOXIC EFFECTS ON HUMANS: No additional
remark.
7
_________________________________________________________________
ECOLOGICAL INFORMATION
_________________________________________________________________
ECOTOXICITY: Not available.
BOD5 AND COD: Not available.
PRODUCTS OF BIODEGRADATION: These products of degradation are
more toxic.
TOXICITY OF THE PRODUCTS OF BIODEGRADATION: The products of
degredation are more toxic.
SPECIAL REMARKS ON THE PRODUCTS OF BIODEGRADATION: No additional
remark.
_________________________________________________________________
DISPOSAL CONSIDERATIONS
_________________________________________________________________
WASTE DISPOSAL: Recycle to process, if possible. Consult your
local or regional authorities.
_________________________________________________________________
TRANSPORT INFORMATION
_________________________________________________________________
DOT CLASSIFICATION: DOT CLASS 6.1: Poisonous material.
IDENTIFICATION: UN2574 II
SPECIAL PROVISIONS FOR TRANSPORT: No additional remark.
_________________________________________________________________
OTHER REGULATORY INFORMATION
_________________________________________________________________
FEDERAL AND STATE REGULATIONS: The following product(s) is (are)
listed on TSCA: TRITOLYL PHOSPHATE
OTHER REGULATIONS:
OSHA: Hazardous by definition of Hazard Communication
Standard (29 CFR 1910.1200).
CANADIAN ENVIRONMENTAL PROTECTION ACT (CEPA): This product
is on the Domestic Substances List (DSL), and is
acceptable for use under the provisions of CEPA.
OTHER CLASSIFICATIONS:
WHMIS(CANADA): WHMIS CLASS D-1A: Material causing immediate
and serious toxic effects (VERY TOXIC).
8
DSCL (EEC): R28-Very toxic if swallowed.
R20/21-Harmful by inhalation and in contact with
skin.
9
HMIS (U.S.A.):
HEALTH HAZARD: 2
FIRE HAZARD: 1
REACTIVITY: 0
PERSONAL PROTECTION: j
NATIONAL FIRE PROTECTION ASSOCIATION (U.S.A.)
HEALTH: 1
FLAMMABILITY: 1
REACTIVITY: 0
SPECIFIC HAZARD:
PROTECTIVE EQUIPMENT:
Gloves.
Lab Coat.
Vapor respirator. Be sure to use a MSHA/NIOSH approved
respirator equivalent. Wear appropriate is inadequate.
Splash goggles.
10
|