MATERIAL SAFETY DATA SHEET
MSDS DATE:10/18/2007
SECTION 1: PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME: TRYPSIN 1 : 100, POWDER
SYNONYMS: N/A
PRODUCT CODES : 22200
MANUFACTURER: ELECTRON MICROSCOPY SCIENCES
DIVISION: 1560 INDUSTRY ROAD/P.O. BOX 550
ADDRESS: HATFIELD, PA 19440
EMERGENCY PHONE: 215-412-8400
CHEMTREC PHONE: 800-424 -9300
FAX PHONE: 215-412-8450
CHEMICAL NAME: TRYPSIN
CHEMICAL FAMILY: N/A
SECTION 2: COMPOSITION/INFORMATION ON INGREDIENTS
INGREDIENT:
TRYPSIN, USP
CAS NO. % WT % VOL SARA 313 REPORTABLE
9002-07-7 100%
mg/m3
ppm
OSHA PEL-TWA: N/A N/A
OSHA PEL STEL : N/A N/A
OSHA PEL CEILING: N/A N/A
ACGIH TLV-TWA: N/A N/A
ACGIH TLV STEL: N/A N/A
ACGIH TLV CEILING: N/A N/A
SECTION 3: HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW: N/A
ROUTES OF ENTRY: INHALATION. INGESTION.
POTENTIAL HEALTH EFFECTS
EYES: MAY CAUSE EYE IRRRITATION AND POSSIBLE BURNS OF THE EYE. MAY CAUSE RAPID DESTRUCTION
OF THE CORNEA.
SKIN: MAY COUSE SKIN IRRITATION AND A BURNING SENSATON.
INGESTION: MAY CAUSE GASTROINTESTINAL TRACT IRRITATION W ITH NAUSEA, VOMITING, AND DIARRHEA.
IT MAY AFFECT BEHAVIOR (GENERAL ANESTHETIC) AND BLOOD.
INHALATION: MAY CAUSE NOSE AND RESPIRATORY TRACT IRRITATION WITH GLOSSITIS, PHARYNGITIS,
HOARSENESS, AND SYSTEMIC REACTIONS.
ACUTE HEALTH HAZARDS: EYE CONTACT (IRRITANT), INHALATION (LUNG IRRITANT, LUNG SENSITIZER).
SLIGHTLY HAZARDOUS IN CASE OF SKIN CONTACT (IRRITANT), OF INGESTION.
CHRONIC HEALTH HAZARDS: THE SUBSTANCE MAY BE TOXIC TO LUNGS. REPEATED OR PROLONGED
EXPOSURE TO THE SUBSTANCE CAN PRODUCE TARGET ORGANS DAMAGE.
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE:
CARCINOGENICITY EFFECTS: N/A, MUTAGENIC EFFECTS: MUTAGENIC FOR MAMMALIAN SOMATIC CELLS.
PAGE 1 OF 5
MATERIAL SAFETY DATA SHEET
MSDS DATE:10/18/2007
TERATOGENIC EFFECTS: N/A, DEVELOPMENTAL TOXICITY: N/A
OSHA: ACGIH: NTP: IARC:
OTHER:
SECTION 4: FIRST AID MEASURES
EYES: FLUSH WITH WATER FOR 15 MINUTES IF IRRITATION OCCURS. SEEK MEDICAL
ATTENTION
SKIN: WASH WITH SOAP AND WATER. IF IRRITATION OCCURS. SEEK MEDICAL ATTENTION.
INGESTION: DO NOT INDUCE VOMITING UNLESS DIRECTED TO DO SO BY MEDICAL PERSONNEL. NEVER
GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS PERSON. LOOSEN TIGHT CLOTHING. SEEK MEDICAL ATTENTION.
INHALATION: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF
BREATHING IS DIFFICULT, GIVE OXYGEN. SEEK MEDICAL ATTENTION.
NOTES TO PHYSICIANS OR FIRST AID PROVIDERS:N/A
SECTION 5: FIRE-FIGHTING MEASURES
FLAMMABLE LIMITS IN AIR, UPPER: N/A
(% BY VOLUME) LOWER:
FLASH POINT: N/A
F:
C:
METHOD USED:
AUTOIGNITION TEMPERATURE: N/A
F:
C:
NFPA HAZARD CLASSIFICATION
HEALTH: 2 FLAMMABILITY: 1 REACTIVITY: 0
OTHER:
HMIS HAZARD CLASSIFICATION0
HEALTH: 2 FLAMMABILITY: 1 REACTIVITY: 0
PROTECTION:
EXTINGUISHING MEDIA: SMALL FIRE: USE DRY CHEMICAL POWDER.
LARGE FIRE: USE WATER SPRAY, FOG OR FOAM. DO NOT USE WATER JET.
SPECIAL FIRE FIGHTING PROCEDURES: N/A
UNUSUAL FIRE AND EXPLOSION HAZARDS: AS WITH MOST ORGANIC SOLIDS, FIRE IS POSSIBLE AT
ELEVATED TEMPERATURES. FINE DUST DISPERSED IN AIR IN SUFFICIENT CONCENTRATIONS AND THE
PRESENCES OF AN IGNITION SOURCE IS A POTENTIAL DUST EXPLOSION HAZARD.
HAZARDOUS DECOMPOSITION PRODUCTS:
SECTION 6: ACCIDENTAL RELEASE MEASURES
ACCIDENTAL RELEASE MEASURES:: USE APPROPRIATE TOOLS TO PUT THE SPILLED SOLID
IN A CONVENIENT WASTE DISPOSAL CONTAINER. FINISH CLEANING BY SPREADING WATER ON THE CONTAMINATED
SURFACE AND DISPOSE OF ACCORDING TO LOCAL AND REGIONAL AUTHORITY REQUIREMENTS.
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MATERIAL SAFETY DATA SHEET
MSDS DATE:10/18/2007
SECTION 7: HANDLING AND STORAGE
HANDLING AND STORAGE: KEEP CONTAINER TIGHTLY CLOSED. KEEP CONTAINER IN A COOL WELL VENTILATED
AREA. ALTHOUGH IT IS STABLE AT ROOM TEMPERATURE, IT IS PREFERABLE TO STORE IT BETWEEN 0 TO 5 DEGRESS
C N ORDER TO REDUCE DETERIORATION.
OTHER PRECAUTIONS: KEEP LOCKED UP AND AWAY FROM HEAT. KEEP AWAY FROM SOURCES OF IGNITION. DO NOT
INGEST . DO NOT BREATHE DUST. AVOID CONTACT WITH EYES. WEAR SUITABLE PROTECTIVE CLOTHING. KEEP AWAY
AWAY FROM INCOMPATIBLES SUCH AS OXIDIZING AGENTS.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
ENGINEERING CONTROLS: USE PROCESS ENCLOSURES, LOCAL EXHAUST VENTILATION, OR OTHER ENGINEERING
CONTROLS TO KEEP AIRBORNE LEVELS BELOW RECOMMENDED EXPOSURE LIMITS. IF USER OPERATIONS GENERATE
DUST,FUME OR MIST, USE VENTILATION TO KEEP EXPOSURE TO AIRBORNE CONTAMINANTS BELOW THE EXPOSURE
LIMIT.
VENTILATION: N/A
RESPIRATORY PROTECTION: USE AN APPROVED/CERTIFIED RESPIRATOR OR EQUIVALENT.
EYE PROTECTION: SPLASH GOGGLES
SKIN PROTECTION: FULL SUIT, BOOTS, GLOVES
OTHER PROTECTIVE CLOTHING OR EQUIPMENT:
WORK HYGIENIC PRACTICES: WASH THOROUGHLY AFTER HANDLING. WASH CLOTHING BEFORE REUSE.
EXPOSURE GUIDELINES: N/A
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE: SOLID, WHITE TO YELLOWISH.
ODOR: ODORLESS
PHYSICAL STATE: SOLID
pH AS SUPPLIED: N/A
pH (Other):
BOILING POINT: N/A
F:
C:
MELTING POINT: N/A
F:
C:
FREEZING POINT: N/A
F:
C:
VAPOR PRESSURE (mmHg): N/A
@
F:
C:
VAPOR DENSITY (AIR = 1): N/A
@
F:
C:
@
F:
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MATERIAL SAFETY DATA SHEET
MSDS DATE:10/18/2007
C:
EVAPORATION RATE: N/A
BASIS (=1):
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES (con鈥檛)
SOLUBILITY IN WATER: SOLUBLE IN COLD WATER, HOT WATER. INSOLUBLE IN ALCOHOL OR GLYCEROL.
READILY SOLUBLE IN SORENSENS SODIUM PHOSPHATE BUFFER SOLUTION.
PERCENT SOLIDS BY WEIGHT:
PERCENT VOLATILE: N/A
BY WT/ BY VOL @
F:
C:
VOLATILE ORGANIC COMPOUNDS (VOC): N/A
WITH WATER: LBS/GAL
WITHOUT WATER: LBS/GAL
MOLECULAR WEIGHT: N/A
VISCOSITY:
@
F:
C:
SECTION 10: STABILITY AND REACTIVITY
STABILITY: THE PRODUCT IS STABLE
CONDITIONS TO AVOID (STABILITY): EXCESS HEAT, MOISTURE, IMCOMPATIBLE MATERIALS
INCOMPATIBILITY (MATERIAL TO AVOID): REACTIVE WITH OXIDIZING AGENTS.
HAZARDOUS DECOMPOSITION OR BY-PRODUCTS: N/A
HAZARDOUS POLYMERIZATION: WILL NOT OCCUR
CONDITIONS TO AVOID (POLYMERIZATION): N/A
SECTION 11: TOXICOLOGICAL INFORMATION
TOXICOLOGICAL INFORMATION: ACUTE ORAL TOXICITY (ld50): 1450MG/KG {MOUSE}
SECTION 12: ECOLOGICAL INFORMATION
ECOLOGICAL INFORMATION: N/A
SECTION 13: DISPOSAL CONSIDERATIONS
WASTE DISPOSAL METHOD: COMPLY WITH FEDERAL, STATE, LOCAL REGULATIONS.
RCRA HAZARD CLASS: NOT A DOT CONTROLLED MATERIAL (US)
PAGE 4 OF 5
MATERIAL SAFETY DATA SHEET
MSDS DATE:10/18/2007
SECTION 13: DISPOSAL CONSIDERATIONS (con鈥檛)
SECTION 14: TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION
PROPER SHIPPING NAME:
HAZARD CLASS:
ID NUMBER: N/A
PACKING GROUP:
LABEL STATEMENT:
WATER TRANSPORTATION
PROPER SHIPPING NAME:
HAZARD CLASS:
ID NUMBER: N/A
PACKING GROUP:
LABEL STATEMENTS:
AIR TRANSPORTATION
PROPER SHIPPING NAME:
HAZARD CLASS:
ID NUMBER: N/A
PACKING GROUP:
LABEL STATEMENTS:
OTHER AGENCIES:
SECTION 15: REGULATORY INFORMATION
U.S. FEDERAL REGULATIONS
TSCA (TOXIC SUBSTANCE CONTROL ACT): 8(b) INVENTORY; TRYPSIN, USP
CERCLA (COMPREHENSIVE RESPONSE COMPENSATION, AND LIABILITY ACT):N/A
SARA TITLE III (SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT): N/A
311/312 HAZARD CATEGORIES: N/A
313 REPORTABLE INGREDIENTS: N/A
STATE REGULATIONS: N/A
INTERNATIONAL REGULATIONS: N/A
SECTION 16: OTHER INFORMATION
OTHER INFORMATION: N/A
PREPARATION INFORMATION: N/A
DISCLAIMER: IN COMPLIANCE WITH THE OSHA HAZARD COMMUNICATION STANDARD, 2.9 C.F.R
1910. 1200, WE ARE PROVIDING YOU WITH A MSDS FOR THE HAZARDOUS MATERIAL YOU ARE
PURCHASING.
IT IS YOUR RESPONSIBILITY TO EDUCATE YOUR EMPLOYEES ON THE SAFE USE OF THE HAZARDOUS
MATERIAL.
ELECTRON MICROSCOPY SCIENCES MAKES NO PRESENTATION AS TO THE ACCURACY OF THE
INFORMATION IN THE MSDS. THE INFORMATION IS BELIEVED TO BE CORRECT; HOWEVER, YOU
(THE CUSTOMER), SHOULD PERFORM YOUR OWN INVESTIGATION AND INDEPENDENT
VERIFICATION. IF YOU RESELL THE PRODUCT, YOU ARE RESPONSIBLE TO FORWARD THE
INFORMATION IN THE MSDS TO YOUR CUSTOMER.
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