EMS CATALOG NO: 26030-XX
EMS PRODUCT: GILLS HEMATOXYLIN
DATE: JUNE 19, 2000
PAGE NUMBER: ONE OF FOUR
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
321 MORRIS ROAD
P.O. BOX 251
FORT WASHINGTON, PA 19034 24 HOUR EMERGENCY PHONE NUMBER
(215) 646-1566 CHEMTREC: (800) 424-9300
_________________________________________________________________
FOR PRODUCT AND SALES INFORMATION
_________________________________________________________________
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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IDENTITY (AS USED ON LABEL AND LIST): Gill's Hematoxylin #3
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HAZARDOUS INGREDIENTS/IDENTITY INFORMATION
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HAZARDOUS COMPONENTS
CHEMICAL: HEMATOXYLIN (C16H1406) (Natural Black 1)
CAS# 517-28-2
OSHA PEL: N/A
ACGIH TLV: N/A
OTHER LIMITS RECOMMENDED: N/A TXDS
% (OPTIONAL): 0.6
CHEMICAL: Aluminum Sulfate (Al2(SO4).18H2O)
CAS# 7784-31-8
OSHA PEL: N/A
ACGIH TLV: 2mg/M3
OTHER LIMITS RECOMMENDED: 2PR-MUS LD-50 270MG/KG
% (OPTIONAL): 5.28
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CHEMICAL: Glacial Acetic Acid (CH3COOH) (Ethanoic Acid, Methane
Carboxylic Acid, Ethylic Acid)
CAS# 64-19-7
OSHA PEL: 25mg/m3
ACGIH TLV: 10ppm
OTHER LIMITS RECOMMENDED:
TOXICITY: LD50 (oral-rat) (mg/Kg)-3310
LD50 (iv-mouse) (mg/Kg)-525
LD50 (skin-rabbit) (mg/kg)-1060
Ld (inhl-mouse) (ppm) -5620
% (OPTIONAL): 6
CHEMICAL: SODIUM IODATE (NaIO3)
CAS# 7681-55-2
OSHA PEL: N/A
ACGIH TLV: N/A
OTHER LIMITS RECOMMENDED: TXDS oral hmnLDLo: 50mg/kg
% (OPTIONAL): 0.06
CHEMICAL: ETHYLENE GLYCOL 1, 2-ETHANEDIOL (HOC2H4OH)
CAS# 107-21-1
OSHA PEL: N/A
ACGIH TLV: 100ppm
OTHER LIMITS RECOMMENDED: TXDS:LD-50 7.5GM/KG MICE
% (OPTIONAL): 25
*** HEMATOXYLIN IS A SUSPECTED CARCINOGEN !!!
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PHYSICAL/CHEMICAL CHARACTERISTICS
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BOILING POINT: N/A
VAPOR PRESSURE (MM/HG.): N/A
VAPOR DENSITY (AIR=1): N/A
SPECIFIC GRAVITY (H20=1): N/A
MELTING POINT: N/A
EVAPORATION RATE (BUTYL ACETATE=1): N/A
SOLUBILITY IN WATER: Yes
APPEARANCE AND ODOR: Purplish-red liquid: odor of acetic acid
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FIRE AND EXPLOSION HAZARD
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FLASH POINT: N/A
FLAMMABLE LIMITS: N/A
LEL:
UEL:
EXTINGUISHING MEDIA: Carbon Dioxide, Dry Chemical
SPECIAL FIRE FIGHTING PROCEDURES: Wear full protective gear and
self-contained breathing apparatus operated in the positive
pressure mode. Emits toxic and corrosive fumes under fire
conditions.
UNUSUAL FIRE AND EXPLOSION HAZARDS: No information is available.
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REACTIVITY DATA
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STABILITY: The product is stable.
CONDITIONS TO AVOID: Flame and intense heat.
INCOMPATIBILITY: Strong oxidizers
HAZARDOUS DECOMPOSITION OR BY-PRODUCTS: N/A
HAZARDOUS POLYMERIZATION: Will not occur.
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HEALTH HAZARD DATA
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ROUTES OF ENTRY:
INHALATION: YES
SKIN: YES
INGESTION: YES
HEALTH HAZARDS: Harmful if inhaled or ingested. Irritant to
skin, eyes and respiratory tract. Hematoxylin is a cancer
suspect agent! Avoid all routes of exposure. Prolonged or
repeated breathing of vapor can cause drunkenness rapidly
passing into a coma associated with a serious or fatal
kidney injury.
CARCINOGENICITY: Yes
NTP: N/A
IARC MONOGRAPHS: N/A
OSHA REGULATED? N/A
SIGNS AND SYMPTOMS OF EXPOSURE: Irritation of the respiratory
tract, burns to the skin and eyes, burning to mouth and
stomach, vomiting, loss of consciousness, and lung damage.
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE: N/A
EMERGENCY AND FIRST AID PROCEDURES: Get medical attention for
all cases of overexposure.
CONTACT: Flush with plenty of water for at least 15 minutes.
CALL A PHYSICIAN for eyes.
INHALATION: Remove to fresh air. If not breathing, administer
artificial respiration. If breathing is difficult,
administer oxygen. CALL A PHYSICIAN!
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PRECAUTIONS FOR SAFE HANDLING AND USE
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STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: Cover
spill with soda ash, mix and form slurry. Scoop into
beaker, dilute with water and neutralize. Place in a
suitable container for disposal.
WASTE DISPOSAL METHOD: Dispose of following federal, state and
local regulations. Contact a professional waste disposal
service.
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORING: Use care in
handling - store in controlled room temperature. Avoid
contact with skin, eyes and clothing. Remove contaminated
clothing and wash before reuse. Do not breathe vapors; use
with adequate ventilation. Wash thoroughly after handling.
OTHER PRECAUTIONS: USE CARE WHEN HANDLING!!
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CONTROL MEASURES
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RESPIRATORY PROTECTION: Sufficient to prevent inhalation of mist
and fumes.
VENTILATION: Local exhaust, mechanical, fume hood.
PROTECTIVE GLOVES: Rubber
EYE PROTECTION: Face shield/ Safety goggles
OTHER PROTECTIVE CLOTHING OR EQUIPMENT: Approved work clothes.
WORK/HYGIENIC PRACTICES: Use care in handling.
N/A=NOT APPLICABLE OR NOT AVAILABLE.
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