EMS CATALOG NO: 26043-05,06 & 10
EMS PRODUCT: Mayer's Hematoxylin
DATE: June 17, 2001
PAGE NUMBER: One of 4
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
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FOR PRODUCT AND SALES INFORMATION
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CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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HAZARDOUS INGREDIENTS/IDENTITY INFORMATION
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PRODUCT NAME: Mayer's Hematoxylin
ALUMINUM AMMONIUM SULFATE, 12-HYDRATE 5%
CAS NO. 7784-26-1
FORMULA: A1NH4(SO4)2-12H2O
SYNONYMS: Ammonium Alum
NIOSH/RTECS NO: N/A
TOXICITY: Orl-rat LD50:2750 mg/kg
OSHA PEL: 2mg/M3 (TWA) soluble salts as Al
ACGIH TLV: 2mg/M3 (TWA) soluble salts as Al
CHLORAL HYDRATE DEA SCHEDULE IV ITEM 5%
CAS NO: 302-17-0
RTECS NO: FM8750000
SYNONYMS: 2,2,2,-Trichloro-1,1-Ethanediol
TOXICITY DATA: orl-hmn LDLO: 4mg/kg unr-man LDLO: 103mg/kg
orl-rat LD50:480mg/kg ipr-rat LD50: 472mg/kg
par-rat LD50:710mg/kg orl-mus LD50: 1100mg/kg
ipr-mus LD50:777mg/kg
1
CITRIC ACID, ANHYDROUS 0.1%
CAS NO: 77-92-9
FORMULA: HOC(CCCH) (CH2000H)2
SYNONYMS: 2-Hydroxy-1,2,3,-Propanetricarboxylic Acid
NIOSH/RTECS NO: GE7350000
TOXICITY: orl-mus LD50:5040mg/kg
ipr-mus LD50: 961mg/kg
scu-mus LD50:2700mg/kg
HEMATOXYLIN, certified 0.1%
C.I. 75290 CAS#: 517-28-2
FORMULA: C16H14O6
SYNONYMS: 7,11b-Dihydrobenz(b)indeno(1,2-d)pyran-3,4,6a,9,
10(6H)-pentol; Natural Black 1
RTECS NO: MH7875000
TOXICITY DATA NOT AVAILABLE. HEMATOXYLIN IS A CANCER SUSPECT AGENT!
SODIUM IODATE 0.02%
CAS NO: 7681-55-2
FORMULA: NaIO3
SYNONYMS: Iodic Acid; Sodium Salt
RTECS NO: NN1400000
TOXICITY DATA: 1pr-mus LD50/119mg/kg 1vn-mus LD50:108mg/kg
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PHYSICAL/CHEMICAL CHARACTERISTICS
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BOILING POINT: N/A
SPECIFIC GRAVITY(H2O=1: N/A
VAPOR PRESSURE(mmHg.): N/A
MELTING POINT: N/A
VAPOR DENSITY(AIR=1): N/A
EVAPORATION RATE: N/A (Butyl acetate=1)
SOLUBILITY IN WATER: Yes
APPEARANCE/ODOR: Dark purplish-red liquid; aqueous solution.
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FIRE AND EXPLOSION HAZARD DATA
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FLASH POINT(Method Used): Not flammable
FLAMMABLE LIMITS: LEL: UEL:
EXTINGUISHING MEDIA:
Use extinguishing media appropriate for surrounding fire.
SPECIAL FIRE FIGHTING PROCEDURES:
Firefighters must wear proper protective gear and self-contained
breathing apparatus with full face shield operated in positive
pressure mode.
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UNUSUAL FIRE AND EXPLOSION HAZARDS: May emit toxic fumes when heated.
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REACTIVITY DATA
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UNSTABLE ___ STABLE _X_
CONDITIONS TO AVOID: N/A
INCOMPATIBILITY (Materials to Avoid): N/A
HAZARDOUS DECOMPOSITION OR BYPRODUCTS: Ammonia, oxides of sulfur.
HAZARDOUS POLYMERIZATION: May Occur___Will Not Occur: _X_
CONDITIONS TO AVOID: N/A
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HEALTH HAZARD DATA
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ROUTE(s) OF ENTRY: Inhalation. Skin. Ingestion.
HEALTH HAZARDS (ACUTE AND CHRONIC):
HEMATOXYLIN IS A CANCER SUSPECT AGENT!
Mayer's Hematoxylin is harmful if inhaled, swallowed or absorbed
through skin-may cause drowsiness, gastritus, nausea, vomiting,
and central nervous system depression.
CARCINOGENICITY:
NTP?: N/A IARC Monographs?: N/A OSHA Regulated?: N/A
SIGNS AND SYMPTOMS OF EXPOSURE: Respiratory irritation and/or
allergic skin reaction.
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE: N/A
EMERGENCY AND FIRST AID PROCEDURES:
INGESTION: If swallowed and conscious, immediately give large
amounts of water. Get medical attention!
INHALATION: If a person breathes in large amounts, move the
exposed person to fresh air.
SKIN CONTACT: In case of contact, immediately wash skin with
plenty of soap & water for at least 15 minutes.
EYE CONTACT: In case of eye contact, immediately flush with
plenty of water for at least 15 minutes.
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PRECAUTIONS FOR SAFE HANDLING AND USE
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STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED:
Wearing suitable protective clothing and gear, absorb spill with
earth or vermiculite and containerize for proper disposal. Wash
spill area with water.
3
WASTE DISPOSAL METHOD:
In accordance with all current local, State and Federal
environmental regulations.
OTHER PRECAUTIONS:
Avoid contact with skin, eyes, and clothing. Wash thoroughly
after handling. Avoid prolonged breathing of vapors. Mayer's
Hematoxylin is air and light sensitive-store properly.
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CONTROL MEASURES
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RESPIRATORY PROTECTION (Specify Type):
VENTILATION:
Local Exhaust: Yes Special: N/A
Mechanical(General): Yes Other: N/A
PROTECTIVE GLOVES: Rubber
EYE PROTECTION: Safety goggles
OTHER PROTECTIVE CLOTHING OR EQUIPMENT: Approved work clothes.
WORK/HYGIENIC PRACTICES: Use care when handling. Avoid all
routes of exposure.
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