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MSDS Material Safety Data Sheet
CAS

75-12-7
052-00-8
7732-18-5

File Name: fermentas_com---sm1833_eu.asp
Trade name:
RiboRuler鈩? Low Range RNA Ladder, ready-to-use
#SM1833

Supplied with: 2x RNA Loading Dye
Page 1/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

1 Identification of the substance/preparation and of the company/undertaking
路 Product details
路 Trade name: RiboRuler鈩? Low Range RNA Ladder, ready-to-use
路 Application of the substance / the preparation: Laboratory chemicals
路 Manufacturer/Supplier:
Fermentas UAB
V.Graiciuno 8
LT-02241 Vilnius
Lithuania
Tel.: +370 5 2602131
Fax.: +370 5 2602142
路 Further information obtainable from:
Please visit our site: http://www.fermentas.com/
Contact us: info@fermentas.lt
Or contact Fermentas distributor in your country.
路 Information in case of emergency:
Poison Information Centre, Mainz, Germany,
Tel.: +49 (0)6131 19240 / 24h


2 Hazards identification
路 Hazard description:


T Toxic


路 Information concerning particular hazards for human and environment:
The product has to be labelled due to the calculation procedure of the "General Classification
guideline for preparations of the EU" in the latest valid version.
R 61 May cause harm to the unborn child.
路 Classification system:
The classification is according to the latest editions of the EU-lists, and extended by company and
literature data.


3 Composition/information on ingredients
路 Chemical characterization
路 Description: Solution, consisting of the following components.
路 Components:
CAS: 75-12-7 formamide Repr. Cat. 2; T; R 61 >50%
EINECS: 200-842-0
EU Number: 616-052-00-8
CAS: 7732-18-5 water 25-50%
EINECS: 231-791-2
(Contd. on page 2)
EU




DR
Page 2/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: RiboRuler鈩? Low Range RNA Ladder, ready-to-use

(Contd. of page 1)
路 Other components:
Components not listed here are not dangerous or their concentrations do not exceed the limits
specified in the EU directive 1999/45/EC.
路 Additional information: For the wording of the listed risk phrases refer to section 16.


4 First aid measures
路 After inhalation: Supply fresh air; consult doctor in case of complaints.
路 After skin contact: Generally the product does not irritate the skin.
路 After eye contact: Rinse opened eye for several minutes under running water.
路 After swallowing: If symptoms persist consult doctor.


5 Fire-fighting measures
路 Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
路 Protective equipment: No special measures required.


6 Accidental release measures
路 Person-related safety precautions: Not required.
路 Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
路 Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.


7 Handling and storage
路 Handling:
路 Information for safe handling:
Ensure good ventilation/exhaustion at the workplace.
Open and handle receptacle with care.
Prevent formation of aerosols.
路 Information about fire and explosion protection: Keep respiratory protective device available.
路 Storage:
路 Requirements to be met by storerooms and receptacles: No special requirements.
路 Information about storage in one common storage facility: Not required.
路 Further information about storage conditions: None.


8 Exposure controls/personal protection
路 Ingredients with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be
monitored at the workplace.
路 Additional information: The lists valid during the making were used as basis.
(Contd. on page 3)
EU




DR
Page 3/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: RiboRuler鈩? Low Range RNA Ladder, ready-to-use

(Contd. of page 2)

路 Personal protective equipment:
路 General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Store protective clothing separately.
路 Respiratory protection:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer
exposure use self-contained respiratory protective device.
路 Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the
preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the
degradation
路 Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of
quality and varies from manufacturer to manufacturer. As the product is a preparation of several
substances, the resistance of the glove material can not be calculated in advance and has therefore to
be checked prior to the application.
路 Penetration time of glove material
The exact break trough time has to be found out by the manufacturer of the protective gloves and has
to be observed.
路 Eye protection: Goggles recommended during refilling


9 Physical and chemical properties
路 General Information
Solution
Form:
Blue
Colour:
Nearly odourless
Odour:
路 Change in condition
Melting point/Melting range: Undetermined.
Boiling point/Boiling range: Undetermined.
Not applicable.
路 Flash point:
Product is not selfigniting.
路 Self-igniting:
Product does not present an explosion hazard.
路 Danger of explosion:
1,06 g/cm鲁
路 Density at 20掳C:
路 Solubility in / Miscibility with
Fully miscible.
water:



10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided:
No decomposition if used according to specifications.
路 Dangerous reactions: No dangerous reactions known.
(Contd. on page 4)
EU




DR
Page 4/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: RiboRuler鈩? Low Range RNA Ladder, ready-to-use

(Contd. of page 3)
路 Dangerous decomposition products: No dangerous decomposition products known.


11 Toxicological information
路 Acute toxicity:
路 LD/LC50 values relevant for classification:
75-12-7 formamide
Oral LD50 5570 mg/kg (rat)
路 Primary irritant effect:
路 on the skin: No irritant effect.
路 on the eye: No irritating effect.
路 Sensitization: No sensitizing effects known.
路 Additional toxicological information:
The product shows the following dangers according to the calculation method of the General EU
Classification Guidelines for Preparations as issued in the latest version:
May cause harm to the unborn child.


12 Ecological information
路 General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage
system.


13 Disposal considerations
路 Product:
路 Recommendation:
Must not be disposed together with household garbage. Do not allow product to reach sewage system.
路 Uncleaned packaging:
路 Recommendation: Disposal must be made according to official regulations.
路 Recommended cleansing agents: Water, if necessary together with cleansing agents.


14 Transport information
路 Land transport ADR/RID (cross-border):
路 ADR/RID class: -
路 Maritime transport IMDG:
-
路 IMDG Class:
路 Marine pollutant: No
路 Air transport ICAO-TI and IATA-DGR:
路 ICAO/IATA Class: -
EU
(Contd. on page 5)




DR
Page 5/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: RiboRuler鈩? Low Range RNA Ladder, ready-to-use

(Contd. of page 4)


15 Regulatory information
路 Labelling according to EU guidelines:
The product has been classified and marked in accordance with EU Directives.
路 Code letter and hazard designation of product:
T Toxic
路 Hazard-determining components of labelling:
formamide
路 Risk phrases:
61 May cause harm to the unborn child.
路 Safety phrases:
53 Avoid exposure - obtain special instructions before use.
20 When using do not eat or drink.
23 Do not breathe gas/fumes/vapour/spray.
36/39 Wear suitable protective clothing and eye/face protection.
45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
60 This material and its container must be disposed of as hazardous waste.


16 Other information
This information is based on our present knowledge and shall be used only as a guide. However,
this shall not constitute a guarantee for any specific product features and shall not establish a legally
valid contractual relationship. Fermentas is not held liable for any damage resulting from handling or
from contact with the above mentioned products.
MSDS has been prepared in accordance with EC regulation 1907/2006/EC and other European
Union legislation in force.
路 Relevant R-phrases
61 May cause harm to the unborn child.
EU




DR
Page 1/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

1 Identification of the substance/preparation and of the company/undertaking
路 Product details
路 Trade name: 2x RNA Loading Dye
. (2x RNA Loading Dye Solution)

路 Application of the substance / the preparation: Laboratory chemicals
路 Manufacturer/Supplier:
Fermentas UAB
V.Graiciuno 8
LT-02241 Vilnius
Lithuania
Tel.: +370 5 2602131
Fax.: +370 5 2602142
路 Further information obtainable from:
Please visit our site: http://www.fermentas.com/
Contact us: info@fermentas.lt
Or contact Fermentas distributor in your country.
路 Information in case of emergency:
Poison Information Centre, Mainz, Germany,
Tel.: +49 (0)6131 19240 / 24h


2 Hazards identification
路 Hazard description:


T Toxic


路 Information concerning particular hazards for human and environment:
The product has to be labelled due to the calculation procedure of the "General Classification
guideline for preparations of the EU" in the latest valid version.
R 61 May cause harm to the unborn child.
路 Classification system:
The classification is according to the latest editions of the EU-lists, and extended by company and
literature data.


3 Composition/information on ingredients
路 Chemical characterization
路 Description: Solution, consisting of the following components.
(Contd. on page 2)
EU




DR
Page 2/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: 2x RNA Loading Dye

(Contd. of page 1)
路 Components:
CAS: 75-12-7 formamide Repr. Cat. 2; T; R 61 >50%
EINECS: 200-842-0
EU Number: 616-052-00-8
CAS: 7732-18-5 water 2,5-10%
EINECS: 231-791-2
路 Other components:
Components not listed here are not dangerous or their concentrations do not exceed the limits
specified in the EU directive 1999/45/EC.
路 Additional information: For the wording of the listed risk phrases refer to section 16.


4 First aid measures
路 After inhalation: Supply fresh air; consult doctor in case of complaints.
路 After skin contact: Generally the product does not irritate the skin.
路 After eye contact: Rinse opened eye for several minutes under running water.
路 After swallowing: If symptoms persist consult doctor.


5 Fire-fighting measures
路 Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
路 Protective equipment: No special measures required.


6 Accidental release measures
路 Person-related safety precautions: Not required.
路 Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
路 Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.


7 Handling and storage
路 Handling:
路 Information for safe handling:
Ensure good ventilation/exhaustion at the workplace.
Open and handle receptacle with care.
Prevent formation of aerosols.
路 Information about fire and explosion protection: Keep respiratory protective device available.
路 Storage:
路 Requirements to be met by storerooms and receptacles: No special requirements.
路 Information about storage in one common storage facility: Not required.
(Contd. on page 3)
EU




DR
Page 3/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: 2x RNA Loading Dye

(Contd. of page 2)
路 Further information about storage conditions: None.


8 Exposure controls/personal protection
路 Ingredients with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be
monitored at the workplace.
路 Additional information: The lists valid during the making were used as basis.
路 Personal protective equipment:
路 General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Store protective clothing separately.
路 Respiratory protection:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer
exposure use self-contained respiratory protective device.
路 Protection of hands:
Due to missing tests no recommendation to the glove material can be given for the product/ the
preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the
degradation
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
路 Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of
quality and varies from manufacturer to manufacturer. As the product is a preparation of several
substances, the resistance of the glove material can not be calculated in advance and has therefore to
be checked prior to the application.
路 Penetration time of glove material
The exact break trough time has to be found out by the manufacturer of the protective gloves and has
to be observed.
路 Eye protection: Goggles recommended during refilling


9 Physical and chemical properties
路 General Information
Solution
Form:
Blue
Colour:
Nearly odourless
Odour:
路 Change in condition
Melting point/Melting range: Undetermined.
Boiling point/Boiling range: Undetermined.
Not applicable.
路 Flash point:
Product is not selfigniting.
路 Self-igniting:
Product does not present an explosion hazard.
路 Danger of explosion:
1,13 g/cm鲁
路 Density at 20掳C:
(Contd. on page 4)
EU




DR
Page 4/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: 2x RNA Loading Dye

(Contd. of page 3)

路 Solubility in / Miscibility with
Fully miscible.
water:



10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided:
No decomposition if used according to specifications.
路 Dangerous reactions: No dangerous reactions known.
路 Dangerous decomposition products: No dangerous decomposition products known.


11 Toxicological information
路 Acute toxicity:
路 LD/LC50 values relevant for classification:
75-12-7 formamide
Oral LD50 5570 mg/kg (rat)
路 Primary irritant effect:
路 on the skin: No irritant effect.
路 on the eye: No irritating effect.
路 Sensitization: No sensitizing effects known.
路 Additional toxicological information:
The product shows the following dangers according to the calculation method of the General EU
Classification Guidelines for Preparations as issued in the latest version:
May cause harm to the unborn child.


12 Ecological information
路 General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage
system.


13 Disposal considerations
路 Product:
路 Recommendation:
Must not be disposed together with household garbage. Do not allow product to reach sewage system.
路 Uncleaned packaging:
路 Recommendation: Disposal must be made according to official regulations.
路 Recommended cleansing agents: Water, if necessary together with cleansing agents.


14 Transport information
路 Land transport ADR/RID (cross-border):
路 ADR/RID class: -
(Contd. on page 5)
EU




DR
Page 5/5
MATERIAL SAFETY DATA SHEET
Prepared according to 1907/2006/EC, Article 31
Printed: 14.01.2008 Revised: 14.01.2008

Trade name: 2x RNA Loading Dye

(Contd. of page 4)

路 Maritime transport IMDG:
-
路 IMDG Class:
路 Marine pollutant: No
路 Air transport ICAO-TI and IATA-DGR:
路 ICAO/IATA Class: -



15 Regulatory information
路 Labelling according to EU guidelines:
The product has been classified and marked in accordance with EU Directives.
路 Code letter and hazard designation of product:
T Toxic
路 Hazard-determining components of labelling:
formamide
路 Risk phrases:
61 May cause harm to the unborn child.
路 Safety phrases:
53 Avoid exposure - obtain special instructions before use.
20 When using do not eat or drink.
23 Do not breathe gas/fumes/vapour/spray.
36/39 Wear suitable protective clothing and eye/face protection.
45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
60 This material and its container must be disposed of as hazardous waste.


16 Other information
This information is based on our present knowledge and shall be used only as a guide. However,
this shall not constitute a guarantee for any specific product features and shall not establish a legally
valid contractual relationship. Fermentas is not held liable for any damage resulting from handling or
from contact with the above mentioned products.
MSDS has been prepared in accordance with EC regulation 1907/2006/EC and other European
Union legislation in force.
路 Relevant R-phrases
61 May cause harm to the unborn child.
EU




DR

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