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Material Safety Data Sheet
SALICYLIC ACID
1: Chemical Product and Company Identification
Product Name: SALICYLIC ACID
Contact information:
Catalog Code: 714190
bioWORLD
4150 Tuller Rd
CAS#: 69-72-7
Suite 228, Dublin, OH 43017, USA
RTECS: VO0525000
For information, call: 614-792-8680
Fax Number: 614-792-8685
TSCA: TSCA 8(b) inventory: Salicylic acid
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: 2-hydroxybenzoicacid; o-hydroxy benzoic acid;
In Case of a chemical emergency, call CHEMTREC
Benzoic acid, 2-hydroxy-.
(24 hours a day) at 1-800-424-9300
Chemical Name: Salicylic Acid
For non-emergency assistance,call: 1-800-860-9729
Chemical Formula: C7H6O3
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
SALICYLIC ACID 69-72-7 >99
Toxicological Data on Ingredients:
LD50 (Oral, Rat): 891 mg/kg
LC50 (Inhalation, Rat): > 900 mg/m3
LD50 (Oral, Mouse): 480 mg/kg
LD50 (Oral, Rabbit): 1300 mg/kg
LD50 (Skin, Rabbit): > 10000 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Harmful.
Harmful if swallowed. Risk of serious damage to eyes.
Target organ(s): Central nervous system. Blood.
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Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention immediately.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient.
Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
attention.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek
immediate medical attention.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Serious Inhalation: Not available.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing
such as a collar, tie, belt or waistband.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: 545 掳C (1013 掳F)
Flash Points: 157 掳C (314.6 掳F).
Flammable Limits: 1.1%
Product of Combustion: Carbon monoxide, Carbon dioxide.
Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
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Special Remarks on Explosion Hazards: Dust-Air mixtures may pose an explosion hazard.
6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Poisonous solid. Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use
water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
sources. Call for assistance on disposal. Finish cleaning by spreading water on the contaminated surface and allow to
evacuate through the sanitary system.
7: Handling and Storage
Precautions: Keep locked up. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire
risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe
dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested,
seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from
incompatibles such as oxidizing agents, moisture.
Storage: LIGHT SENSITIVE. MOISTURE SENSITIVE. Store in light resistant containers. Keep container tightly closed.
Keep container in a cool, well-ventilated area. Do not store above 23掳C (73.4掳F).
8: Exposure Controls/Personal Protection
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protection: Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or
equivalent. Gloves.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained
breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient;
consult a specialist BEFORE handling this product.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid. (Crystalline granules )
Odor: Odorless.
Taste: Sweetish , afterward acrid
Molecular Weight: 138.12 g/mole
Color: White.
pH(1% soln/water): 2.4.
Boiling Point: Decomposition temperature: 211掳C (411.8掳F)
Melting Point: 159 掳C (318.2 掳F)
Critical Temperature: Not available.
Specific Gravity: 1.443 (Water = 1)
Vapour Pressure: 1.0
Vapor Density: 4.8 (Air = 1)
Volatility: Not available.
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Odor Threshold: Not available.
Water/Oil Dist. Coeff: The product is more soluble in oil; log(oil/water) = 2.3
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, acetone.
Solubility: Soluble in acetone. Partially soluble in cold water. Very slightly soluble in hot water.
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: Excessive heat, excessive dust generation, Incompatible materials. Dust-Air mixtures
Incompatibility with various substances: Reactive with oxidizing agents, moisture.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Light, moisture, Iron salts, spirt nitrous ether, lead acetate, iodine
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Absorbed through skin. Inhalation. Ingestion.
Toxicity to Animals:
LD50 (Oral, Rat): 891 mg/kg
LC50 (Inhalation, Rat): > 900 mg/m3
LD50 (Skin, Rat): > 2000 mg/kg
LD50 (Intraperitoneal, Rat): 157 mg/kg
LD50 (Oral, Mouse): 480 mg/kg
LD50 (Intraperitoneal, Mouse): 300 mg/kg
LD50 (Intravenous, Mouse): 184 mg/kg
LD50 (Oral, Rabbit): 1300 mg/kg
LD50 (Skin, Rabbit): > 10000 mg/kg
LC50 (Inhalation, Mammal): > 300 mg/m3
Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Development toxin [POSSIBLE].
Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant), of ingestion, of inhalation (lung irritant).
Slightly hazardous in case of skin contact (permeator).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May affect genetic material (mutagenicity) based on animal studies.
May cause adverse reproductive effects. Teratorgenic, Embryotoxic and/or foetotoxic in animal studies. Human: Transferred
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into maternal breast milk.
Special Remarks on other Toxic Effects on Humans: Skin: May be harmful through skin absorption, May cause skin
irritation. May affect the cardiovascular system (increase in blood pressure), and metabolism (body temperature increase) if
absorbe through skin
Eye: Causes eye irritation, temporary injury.
Inhalation: Causes irritation of the respiratory system (coughing, difficult breathing), ringing in the ears, confusion, rapid
pulse, headache, dizziness, nausea, and vomiting.
Ingestion: May be harmful if swallowed in large amounts. Causes irritation of the gastrointestinal tract (nausea, vomiting
abdominal pains). May affect behavior (muscle weakness and general depressed activity, confusion). May cause ringing in
the ears, rapid breathing, sweating and possible kidney damage. Severe over exposure may result in central nervous system
stimulation followed by depression.
Chronic Potential Health Effects: Possible hypersensitization.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term
degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the
material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe
all federal, state, and local environmental regulations.
14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory: Salicylic acid
Other Regulations: EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xn
Indication of Danger: Harmful.
R: 22 41
Risk Statements: Harmful if swallowed. Risk of serious damage to eyes.
S: 26 39
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear
eye/face protection.
Other Classifications:
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WHMIS(Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
DSCL(EEC): R22- Harmful if swallowed.
R37/38- Irritating to respiratory system and skin.
R41- Risk of serious damage to eyes.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39- Wear suitable gloves and eye/face protection.
HMIS(U.S.A):
Health Hazard: 2
Fire Hazard: 1
Reactivity: 1
Personal Protection: E
National Fire Protection Association (U.S.A):
Health: 2
Flammability: 1
Reactivity: 1
Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Wear appropriate respirator when ventilation is inadequate. Splash goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 31/07/2006 11:21:55 AM
Last Updated: 03/08/2006 2:52:25 PM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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