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MSDS Material Safety Data Sheet
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File Name: austincc_edu---a-amylase.asp
                            SIGMA-ALDRICH

MATERIAL SAFETY DATA SHEET

Date Printed: 01/15/2008
Date Updated: 02/04/2006
Version 1.4


Section 1 - Product and Company Information

Product Name ALPHA-AMYLASE FROM HUMAN SALIVA, TYPE
XIII-A
Product Number A1031
Brand SIGMA

Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555

Section 2 - Composition/Information on Ingredient

Substance Name CAS # SARA 313
A-AMYLASE TYPE IX-A FROM HUMAN None No
SALIVA

Chemical Family Human source material.

Section 3 - Hazards Identification

EMERGENCY OVERVIEW
Biohazard. Harmful.
May cause sensitization by inhalation.
Handle as if capable of transmitting infectious agents.

HMIS RATING
HEALTH: 3*
FLAMMABILITY: 0
REACTIVITY: 0
SPECIAL HAZARD(S): Human Source

NFPA RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 0
SPECIAL HAZARD(S): Human Source

*additional chronic hazards present.

For additional information on toxicity, please refer to Section 11.

Section 4 - First Aid Measures

ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.

INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.

DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.

Section 5 - Fire Fighting Measures

FLASH POINT
N/A

AUTOIGNITION TEMP
N/A

FLAMMABILITY
N/A

EXTINGUISHING MEDIA
Suitable: Use extinguishing media appropriate to surrounding
fire conditions.

FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.

Section 6 - Accidental Release Measures

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Wash spill site with 10% bleach and ventilate area
after material pickup is complete.

Section 7 - Handling and Storage

HANDLING
User Exposure: Avoid inhalation. Avoid contact with eyes, skin,
and clothing. Avoid prolonged or repeated exposure.

STORAGE
Suitable: Keep tightly closed.
Store at -20掳C

Section 8 - Exposure Controls / PPE

ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved
under appropriate government standards such as NIOSH (US) or CEN
(EU). Where risk assessment shows air-purifying respirators are


SIGMA - A1031 www.sigma-aldrich.com Page 2
appropriate use a dust mask type N95 (US) or type P1 (EN 143)
respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.

GENERAL HYGIENE MEASURES
Wash thoroughly after handling.

Section 9 - Physical/Chemical Properties

Appearance Physical State: Solid

Property Value At Temperature or Pressure

Molecular Weight N/A
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A

N/A = not available

Section 10 - Stability and Reactivity

STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

Section 11 - Toxicological Information

ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.


SIGMA - A1031 www.sigma-aldrich.com Page 3
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.

SENSITIZATION
Respiratory: May cause allergic respiratory reaction.

SIGNS AND SYMPTOMS OF EXPOSURE
Potentially biohazardous material.

CONDITIONS AGGRAVATED BY EXPOSURE
The toxicological properties have not been thoroughly
investigated.

Section 12 - Ecological Information

No data available.

Section 13 - Disposal Considerations

APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Disposal should be made in accordance with
existing disposal practices employed for infectious waste at your
institution. Observe all federal, state, and local environmental
regulations.

Section 14 - Transport Information

DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.

IATA
Non-Hazardous for Air Transport: Non-hazardous for air
transport.

Section 15 - Regulatory Information

EU ADDITIONAL CLASSIFICATION
Symbol of Danger: B-Xn
Indication of Danger: Biohazard. Harmful.
R: 42
Risk Statements: May cause sensitization by inhalation.
S: 22-45
Safety Statements: Do not breathe dust. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).

US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Biohazard. Harmful.
Risk Statements: May cause sensitization by inhalation.
Safety Statements: Do not breathe dust. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).
US Statements: Handle as if capable of transmitting infectious
agents.

UNITED STATES REGULATORY INFORMATION


SIGMA - A1031 www.sigma-aldrich.com Page 4
SARA LISTED: No

CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: No
NDSL: No

Section 16 - Other Information

DISCLAIMER
For R&D use only. Not for drug, household or other uses.

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2007 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.




SIGMA - A1031 www.sigma-aldrich.com Page 5

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