PRODUCT #: L3396 NAME: LEAD ACETATE TRIHYDRATE ACS REAGENT
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Wednesday, March 12, 1903 2:26PM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: L3396
NAME: LEAD ACETATE TRIHYDRATE ACS REAGENT
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 6080-56-4
MF: C4H6O4PB
SYNONYMS
ACETIC ACID, LEAD(+2) SALT TRIHYDRATE * BIS(ACETATO)TRIHYDROXYTRILEAD
* BLEIAZETAT (GERMAN) * LEAD DIACETATE TRIHYDRATE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
TOXIC
MAY CAUSE CANCER.
MAY CAUSE HERITABLE GENETIC DAMAGE.
TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
DANGER OF CUMULATIVE EFFECTS.
MAY IMPAIR FERTILITY.
TARGET ORGAN(S):
NERVES
BLOOD
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
DO NOT BREATHE DUST.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN IMMEDIATELY.
DISCARD CONTAMINATED CLOTHING AND SHOES.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
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PRODUCT #: L3396 NAME: LEAD ACETATE TRIHYDRATE ACS REAGENT
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Wednesday, March 12, 1903 2:26PM
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
SAFETY SHOWER AND EYE BATH.
USE ONLY IN A CHEMICAL FUME HOOD.
DO NOT BREATHE DUST.
AVOID ALL CONTACT.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
OFF-WHITE CRYSTALS
PHYSICAL PROPERTIES
SPECIFIC GRAVITY: 2.550
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
MAY DECOMPOSE ON EXPOSURE TO LIGHT.
STRONG ACIDS
ABSORBS CO2 FROM AIR.
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
LEAD/LEAD OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
MAY CAUSE IRRITATION.
MAY CAUSE CONVULSIONS.
CHRONIC EFFECTS
CARCINOGEN.
MAY CAUSE REPRODUCTIVE DISORDERS.
MAY ALTER GENETIC MATERIAL.
TARGET ORGAN(S):
BLOOD
CENTRAL NERVOUS SYSTEM
PERIPHERAL NERVOUS SYSTEM
G.I. SYSTEM
SKELETAL MUSCLE
KIDNEYS
FEMALE REPRODUCTIVE SYSTEM
MALE REPRODUCTIVE SYSTEM
ADDITIONAL INFORMATION
LEAD SALTS HAVE BEEN REPORTED TO CROSS THE PLACENTA AND TO INDUCE
EMBRYO- AND FETO- MORTALITY. THEY ALSO HAVE TERATOGENIC EFFECT IN
SOME ANIMAL SPECIES. NO TERATOGENIC EFFECTS HAVE BEEN REPORTED WITH
EXPOSURE TO ORGANOMETALLIC LEAD COMPOUNDS. ADVERSE EFFECTS OF LEAD ON
HUMAN REPRODUCTION, EMBRYONIC AND FETAL DEVELOPMENT AND POSTNATAL
(E.G., MENTAL) DEVELOPMENT HAVE BEEN REPORTED. EXCESSIVE EXPOSURE CAN
AFFECT BLOOD, NERVOUS AND DIGESTIVE SYSTEMS. THE SYNTHESIS OF
HEMOGLOBIN IS INHIBITED AND RESULTS IN ANEMIA. IF LEFT UNTREATED,
NEUROMUSCULAR DYSFUNCTION, POSSIBLE PARALYSIS AND ENCEPHALOPATHY CAN
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PRODUCT #: L3396 NAME: LEAD ACETATE TRIHYDRATE ACS REAGENT
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Wednesday, March 12, 1903 2:26PM
RESULT. ADDITIONAL SYMPTOMS OF OVEREXPOSURE INCLUDE: JOINT AND MUSCLE
PAIN, WEAKNESS OF THE EXTENSOR MUSCLES (FREQUENTLY THE HAND AND
WRIST), HEADACHE, DIZZINESS, ABDOMINAL PAIN, DIARRHEA, CONSTIPATION,
NAUSEA, VOMITING, BLUE LINE ON THE GUMS, INSOMNIA AND METALLIC TASTE.
HIGH BODY LEVELS PRODUCE INCREASED CEREBROSPINAL PRESSURE, BRAIN
DAMAGE, STUPOR LEADING TO COMA AND OFTEN DEATH.
RTECS #: OF8050000
LEAD ACETATE (II), TRIHYDRATE
TOXICITY DATA
ORL-RAT LD50:4665 MG/KG ATDAEI 1,713,1992
IPR-MUS LD50:174 MG/KG TXAPA9 63,461,1982
TARGET ORGAN DATA
BLOOD (OTHER CHANGES)
EFFECTS ON NEWBORN (GROWTH STATISTICS)
EFFECTS ON NEWBORN (BEHAVIORAL)
EFFECTS ON NEWBORN (PHYSICAL)
EFFECTS ON NEWBORN (OTHER POSTNATAL MEASURES OR EFFECTS)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF
THIS MATERIAL.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
CAUTION: SUBSTANCE NOT YET FULLY TESTED.
TOXIC
R 33
DANGER OF CUMULATIVE EFFECTS.
R 40
POSSIBLE RISK OF IRREVERSIBLE EFFECTS.
R 48/22
HARMFUL: DANGER OF SERIOUS DAMAGE TO HEALTH BY PROLONGED
EXPOSURE IF SWALLOWED.
R 60
MAY IMPAIR FERTILITY.
R 61
MAY CAUSE HARM TO THE UNBORN CHILD.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
S 53
AVOID EXPOSURE - OBTAIN SPECIAL INSTRUCTIONS BEFORE USE.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
IARC CANCER REVIEW:ANIMAL SUFFICIENT EVIDENCE IMEMDT 1,40,1972
NIOSH REL TO LEAD, INORGANIC-AIR:10H TWA <0.1 MG(PB)/M3
NIOSH* DHHS #92-100,1992
NOES 1983: HZD X5250; NIS 3; TNF 95; NOS 3; TNE 845; TFE 433
NTP 7TH ANNUAL REPORT ON CARCINOGENS, 1992 : ANTICIPATED TO BE
CARCINOGEN
U.S. INFORMATION
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PRODUCT #: L3396 NAME: LEAD ACETATE TRIHYDRATE ACS REAGENT
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Wednesday, March 12, 1903 2:26PM
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS -
LEAD COMPOUNDS.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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