PRODUCT #: M2886 NAME: METHYL ETHYL KETONE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 3:40PM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: M2886
NAME: METHYL ETHYL KETONE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 78-93-3
MF: C4H8O
EC NO: 201-159-0
SYNONYMS
ACETONE, METHYL- * AETHYLMETHYLKETON (GERMAN) * BUTANONE * 2-BUTANONE
(OSHA) * BUTANONE 2 (FRENCH) * 3-BUTANONE * ETHYL METHYL CETONE
(FRENCH) * ETHYLMETHYLKETON (DUTCH) * ETHYL METHYL KETONE (DOT) *
KETONE, ETHYL METHYL * MEETCO * MEK (OSHA) * METHYL ACETONE * METHYL
ETHYL KETONE (ACGIH:DOT:OSHA) * METILETILCHETONE (ITALIAN) *
METYLOETYLOKETON (POLISH) * RCRA WASTE NUMBER U159 * UN1193 (DOT) *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
FLAMMABLE (USA)
HIGHLY FLAMMABLE (EU)
IRRITANT
RISK OF SERIOUS DAMAGE TO EYES.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
TARGET ORGAN(S):
CENTRAL NERVOUS SYSTEM
KEEP AWAY FROM SOURCES OF IGNITION - NO SMOKING.
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
FLAMMABLE LIQUID.
VAPOR MAY TRAVEL CONSIDERABLE DISTANCE TO SOURCE OF IGNITION AND
FLASH BACK.
CONTAINER EXPLOSION MAY OCCUR UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
Page 1
PRODUCT #: M2886 NAME: METHYL ETHYL KETONE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 3:40PM
SHUT OFF ALL SOURCES OF IGNITION.
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
ABSORB ON SAND OR VERMICULITE AND PLACE IN CLOSED CONTAINERS FOR
DISPOSAL.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
SAFETY SHOWER AND EYE BATH.
MECHANICAL EXHAUST REQUIRED.
DO NOT BREATHE VAPOR.
AVOID CONTACT WITH EYES, SKIN AND CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
SEVERE EYE IRRITANT.
KEEP TIGHTLY CLOSED.
KEEP AWAY FROM HEAT, SPARKS, AND OPEN FLAME.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
COLORLESS LIQUID
PHYSICAL PROPERTIES
BOILING POINT: 80 C
MELTING POINT: -87 C
FLASHPOINT 26F
-3.33C
EXPLOSION LIMITS IN AIR:
UPPER 10.1%
LOWER 1.8%
AUTOIGNITION TEMPERATURE: 960 F 515C
VAPOR PRESSURE: 71MM 20 C
SOLUBILITY:
WATER -SOLUBLE ETHANOL -SOLUBLE
ETHER -SOLUBLE ACETONE -SOLUBLE
BENZENE -SOLUBLE
SPECIFIC GRAVITY: 0.805
VAPOR DENSITY: 2.49
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
OXIDIZING AGENTS
BASES
STRONG REDUCING AGENTS
PROTECT FROM MOISTURE.
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
CARBON MONOXIDE, CARBON DIOXIDE
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.
CAUSES SEVERE EYE IRRITATION.
CAUSES SKIN IRRITATION.
CAN CAUSE CNS DEPRESSION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
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PRODUCT #: M2886 NAME: METHYL ETHYL KETONE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 3:40PM
EXPOSURE CAN CAUSE:
NAUSEA, DIZZINESS AND HEADACHE
GASTROINTESTINAL DISTURBANCES
DERMATITIS
NARCOTIC EFFECT
TARGET ORGAN(S):
CENTRAL NERVOUS SYSTEM
RTECS #: EL6475000
2-BUTANONE
IRRITATION DATA
EYE-HMN 350 PPM JIHTAB 25,282,1943
SKN-RBT 500 MG/24H MOD JIHTAB 25,282,1943
SKN-RBT 402 MG/24H MLD TXAPA9 19,276,1971
SKN-RBT 13780 UG/24H OPEN MLD AIHAAP 23,95,1962
EYE-RBT 80 MG TXAPA9 19,276,1971
TOXICITY DATA
ORL-RAT LD50:2737 MG/KG TXAPA9 19,699,1971
IHL-RAT LC50:23500 MG/M3/8H AIHAAP 20,364,1959
IPR-RAT LD50:607 MG/KG ENVRAL 40,411,1986
ORL-MUS LD50:4050 MG/KG TOLED5 30,13,1986
IHL-MUS LC50:32 GM/M3/4H CUTOEX 1,47,1993
IPR-MUS LD50:616 MG/KG SCCUR* -,6,1961
SKN-RBT LD50:6480 MG/KG SHELL* MSDS-5390-4
IHL-MAM LC50:38 GM/M3 GISAAA 51(5),61,1986
TARGET ORGAN DATA
SENSE ORGANS AND SPECIAL SENSES (OTHER OLFACTION EFFECTS)
SENSE ORGANS AND SPECIAL SENSES (CONJUNCTIVA IRRITATION)
LUNGS, THORAX OR RESPIRATION (OTHER CHANGES)
LIVER (OTHER CHANGES)
IMMUNOLOGICAL INCLUDING ALLERGIC (OTHER IMMEDIATE)
EFFECTS ON EMBRYO OR FETUS (FETOTOXICITY)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (MUSCULOSKELETAL SYSTEM)
BIOCHEMICAL EFFECTS (LIPIDS INCLUDING TRANSPORT)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND
SCRUBBER BUT EXERT EXTRA CARE IN IGNITING AS THIS MATERIAL IS HIGHLY
FLAMMABLE.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
EC INDEX NO: 606-002-00-3
HIGHLY FLAMMABLE
IRRITANT
R 11
HIGHLY FLAMMABLE.
R 36/37
IRRITATING TO EYES AND RESPIRATORY SYSTEM.
S9
KEEP CONTAINER IN A WELL-VENTILATED PLACE.
S 16
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PRODUCT #: M2886 NAME: METHYL ETHYL KETONE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 3:40PM
KEEP AWAY FROM SOURCES OF IGNITION - NO SMOKING.
S 25
AVOID CONTACT WITH EYES.
S 33
TAKE PRECAUTIONARY MEASURES AGAINST STATIC DISCHARGES.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-STEL 885 MG/M3 (300 PPM) DTLVS* TLV/BEI,1996
ACGIH TLV-TWA 590 MG/M3 (200 PPM) DTLVS* TLV/BEI,1996
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC 54,7740,1989
MSHA STANDARD-AIR:TWA 200 PPM (590 MG/M3)
DTLVS* 3,29,1971
OSHA PEL (GEN INDU):8H TWA 200 PPM (590 MG/M3)
CFRGBR 29,1910.1000,1994
OSHA PEL (CONSTRUC):8H TWA 200 PPM (590 MG/M3)
CFRGBR 29,1926.55,1994
OSHA PEL (SHIPYARD):8H TWA 200 PPM (590 MG/M3)
CFRGBR 29,1915.1000,1993
OSHA PEL (FED CONT):8H TWA 200 PPM (590 MG/M3)
CFRGBR 41,50-204.50,1994
OEL-AUSTRALIA:TWA 150 PPM (445 MG/M3);STEL 300 PPM (890 MG/M3) JAN 1993
OEL-AUSTRIA:TWA 200 PPM (590 MG/M3) JAN 1993
OEL-BELGIUM:TWA 200 PPM (590 MG/M3);STEL 300 PPM (885 MG/M3) JAN 1993
OEL-DENMARK:TWA 100 PPM (290 MG/M3);SKIN JAN 1993
OEL-FINLAND:TWA 150 PPM (440 MG/M3);STEL 190 PPM;SKIN JAN 1993
OEL-FRANCE:TWA 200 PPM (600 MG/M3);SKIN JAN 1993
OEL-GERMANY:TWA 200 PPM (590 MG/M3) JAN 1993
OEL-HUNGARY:TWA 200 MG/M3;STEL 600 MG/M3 JAN 1993
OEL-INDIA:TWA 200 PPM (590 MG/M3);STEL 300 PPM (885 MG/M3) JAN 1993
OEL-JAPAN:TWA 200 PPM (590 MG/M3) JAN 1993
OEL-THE NETHERLANDS:TWA 200 PPM (590 MG/M3) JAN 1993
OEL-THE PHILIPPINES:TWA 200 PPM (590 MG/M3) JAN 1993
OEL-POLAND:TWA 200 MG/M3 JAN 1993
OEL-RUSSIA:TWA 200 PPM;STEL 200 MG/M3 JAN 1993
OEL-SWEDEN:TWA 50 PPM (150 MG/M3);STEL 100 PPM (300 MG/M3) JAN 1993
OEL-SWITZERLAND:TWA 200 PPM (590 MG/M3);STEL 400 PPMJAN 1993
OEL-TURKEY:TWA 200 PPM (590 MG/M3) JAN 1993
OEL-UNITED KINGDOM:TWA 200 PPM (590 MG/M3);STEL 300 PPM JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV
NIOSH REL TO METHYL ETHYL KETONE-AIR:10H TWA 200 PPM;STEL 300 PPM
NIOSH* DHHS #92-100,1992
NOHS 1974: HZD 13980; NIS 319; TNF 64013; NOS 177; TNE 801382
NOES 1983: HZD 13980; NIS 318; TNF 87227; NOS 208; TNE 1447456; TFE
245372
EPA GENETOX PROGRAM 1988, INCONCLUSIVE: B SUBTILIS REC ASSAY
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA 8(A) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
FEREAC 47,26992,82
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
ON EPA IRIS DATABASE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
NIOSH ANALYTICAL METHOD, 1994: METHYL ETHYL KETONE, 2500; IN BLOOD,
8002
OSHA ANALYTICAL METHOD #16
U.S. INFORMATION
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PRODUCT #: M2886 NAME: METHYL ETHYL KETONE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 3:40PM
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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