Material Safety Data Sheet
HMIS
NFPA Personal Protective Equipment
Health Hazard
3
1 Fire Hazard
1
3 0
Reactivity
0 See Section 15.
Section 1. Chemical Product and Company Identification Page Number: 1
Catalog
Chlorpromazine HCl CH132
Common Name/
Number(s).
Trade Name
69-09-0
CAS#
Manufacturer SO1750000
RTECS
SPECTRUM CHEMICAL MFG. CORP.
14422 S. SAN PEDRO STREET TSCA 8(b) inventory:
TSCA
Chlorpromazine HCl
GARDENA, CA 90248
Not available.
Commercial Name(s) Not available.
CI#
2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine
Synonym
IN CASE OF EMERGENCY
hydrochloride
CHEMTREC (24hr) 800-424-9300
Not available.
Chemical Name
Not available. CALL (310) 516-8000
Chemical Family
C17H19ClN2S.HCl
Chemical Formula
SPECTRUM CHEMICAL MFG. CORP.
Supplier
14422 S. SAN PEDRO STREET
GARDENA, CA 90248
Section 2.Composition and Information on Ingredients
Exposure Limits
3
STEL (mg/m3) CEIL (mg/m3)
Name CAS # TWA (mg/m ) % by Weight
1) Chlorpromazine HCl 69-09-0 100
Chlorpromazine HCl:
Toxicological Data
ORAL (LD50): Acute: 145 mg/kg [Rat]. 135 mg/kg [Mouse].
on Ingredients
Section 3. Hazards Identification
Potential Acute Health Effects Extremely hazardous in case of inhalation. Very hazardous in case of skin contact (irritant, permeator), of eye
contact (irritant), of ingestion. Severe over-exposure can result in death. Inflammation of the eye is characterized
by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
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Chlorpromazine HCl
Extremely hazardous in case of inhalation.
Potential Chronic Health
Very hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion.
Effects
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance is toxic to blood, the nervous system, liver.
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to an
highly toxic material may produce general deterioration of health by an accumulation in one or many human
organs. Repeated or prolonged inhalation of dust may lead to chronic respiratory irritation.
Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.
Skin Contact After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin
with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated
clothing before reusing.
Serious Skin Contact Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical attention.
Ingestion Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible
indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen
tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek immediate medical attention.
Serious Ingestion Not available.
Section 5. Fire and Explosion Data
May be combustible at high temperature.
Flammability of the Product
Not available.
Auto-Ignition Temperature
Not available.
Flash Points
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...),
Products of Combustion
halogenated compounds.
Not available.
Fire Hazards in Presence of
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Not available.
Special Remarks on
Fire Hazards
Special Remarks on Explosion Not available.
Hazards
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Chlorpromazine HCl
Section 6. Accidental Release Measures
Small Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill Use a shovel to put the material into a convenient waste disposal container.
Section 7. Handling and Storage
Keep locked up Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,
Precautions
evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not
breathe dust. In case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical
advice immediately and show the container or the label. Avoid contact with skin and eyes
Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly
Storage
closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate
locked safety storage cabinet or room.
Section 8. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits Not available.
Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid.) Not available.
Odor
Not available.
Taste
355.33 g/mole
Molecular Weight
White.
Color
Not available.
pH (1% soln/water)
Decomposes.
Boiling Point
195掳C (383掳F)
Melting Point
Not available.
Critical Temperature
Not available.
Specific Gravity
Not applicable.
Vapor Pressure
Not available.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
Not available.
Dispersion Properties
Not available.
Solubility
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Chlorpromazine HCl
Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Not available.
Conditions of Instability
Not available.
Incompatibility with various
substances
Non-corrosive in presence of glass.
Corrosivity
Not available.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
No.
Polymerization
Section 11. Toxicological Information
Routes of Entry Dermal contact. Eye contact. Inhalation. Ingestion.
Toxicity to Animals Acute oral toxicity (LD50): 135 mg/kg [Mouse].
Chronic Effects on Humans The substance is toxic to blood, the nervous system, liver.
Other Toxic Effects on Extremely hazardous in case of inhalation.
Humans Very hazardous in case of skin contact (irritant, permeator), of ingestion.
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on Not available.
Chronic Effects on Humans
Special Remarks on other Not available.
Toxic Effects on Humans
Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
The products of degradation are more toxic.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation
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Chlorpromazine HCl
Section 13. Disposal Considerations
Waste Disposal
Section 14. Transport Information
DOT Classification CLASS 6.1: Poisonous material.
: Toxic solids n.o.s. : UN2811 PG: Not available.
Identification
Not available.
Special Provisions for
Transport
DOT (Pictograms)
Section 15. Other Regulatory Information and Pictograms
TSCA 8(b) inventory: Chlorpromazine HCl
Federal and State
Regulations
California
Proposition 65
Warnings
Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
Other Classifications WHMIS (Canada)
CLASS D-2B: Material causing other toxic effects (TOXIC).
DSCL (EEC) R38- Irritating to skin.
R41- Risk of serious damage to eyes.
R48/25- Toxic: danger of serious
damage to health in case of prolonged
exposure if swallowed.
Health Hazard
HMIS (U.S.A.) 3 National Fire Protection Flammability
1
Association (U.S.A.)
Fire Hazard
1
0
3
Health Reactivity
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
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Chlorpromazine HCl
ADR (Europe)
(Pictograms)
Protective Equipment Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.
Section 16. Other Information
C4104
MSDS Code
Not available.
References
Other Special Not available.
Considerations
Validated by Sonia Owen on 8/11/2006. Verified by Sonia Owen.
Printed 9/11/2006.
CALL (310) 516-8000
Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper
methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products,
Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
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