**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 10592-13-9 |Doxycycline Hydrochloride | ca 100% | 234-198-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: None Listed.
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. May cause liver damage.
May cause bone structure abnormalities. May be harmful if swallowed.
May produce nervous system disturbances.
Inhalation:
May cause respiratory tract irritation. May cause effects similar to
those described for ingestion.
Chronic:
May cause liver and kidney damage. May cause bone marrow
abnormalities with damage to blood forming tissues. Adverse
reproductive effects have been reported in animals.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Wash clothing before reuse. Flush skin with plenty
of soap and water.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry
chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion
and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep
refrigerated. (Store below 4C/39F.)
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 10592-13-9:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C22H24N2O8HCl
Molecular Weight: 480.6366
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong
oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 10592-13-9: QI8925000
LD50/LC50:
CAS# 10592-13-9: Oral, mouse: LD50 = 1890 mg/kg; Oral, rat: LD50 =
1700 mg/kg.
Carcinogenicity:
Doxycycline Hydrochloride -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 10592-13-9: 2
Canada
CAS# 10592-13-9 is listed on Canada's DSL List.
CAS# 10592-13-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 10592-13-9 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 4/25/2000 Revision #6 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
Bis(Dimethylthiocarbamyl) Sulfide (Pract)
| 97-74-5 |
|
Pregnenolone acetate, 99%
| 1778-02-5 |
|
2-Propylpyrazine, 98+%
| 18138-03-9 |
|
Triphenylmethanesulfonamide, 97+%
| 38499-08-0 |
|
Fast garnet gbc base, 97%
| 97-56-3 |
|
Ibuprofen
| 15687-27-1 |
|
Standard Metal Solutions
| 7647-01-0 |
|
Neomycin Sulfate
| 1405-10-3 |
|
Sarcosine Anhydride, 99%
| 5076-82-4 |
|
1,1'-Thiocarbonyldiimidazole, tech.,90%
| 6160-65-2 |
|
1-(2,4,6-Trichlorophenyl)-3-(P-Nitro-Anilino)-2-Pyrazoline-5-One, 97%
| 34320-82-6 |
|
Phosphotungstic acid, 44-hydrate
| 12067-99-1 |
|
L(+)-Lactic Acid, Free Acid
| 79-33-4 |
|
Doxycycline Hydrochloride
| 10592-13-9 |
|
0.05M Perchloric acid in Propan-1-ol
| 71-23-8 |
|
Custom Made Multi-Element Standard
| 1327-53-3 |
|
FisherBrand Citrisolv
| 5989-27-5 |
|
0.5M EDTA (DEPC) Solution
| 60-00-4 |
|
1,4-Dihydroxynaphthalene, 1:1 Mixture with 1,4-Naphthoquinone
| 571-60-8 |
|
Tetrahydrofuran, Stabilized, Anhydrous, 99.9%, 50ppm Water
| 109-99-9 |
|
Ethyl 4-methylphenylacetate, 98%
| 14062-19-2 |
|
Tetrahydrofuran, Anhydrous, 99.9%, 50ppm Water
| 109-99-9 |
|
Dichloromethane, Anhydrous, 99.9%
| 75-09-2 |
|
4-Nitrophenyl phenyl ether, 99%
| 620-88-2 |
|
N,N-Dimethylformamide, Anhydrous, 99.8%
| 68-12-2 |
|
Toluene, Anhydrous, 99.8%, 50ppm Water
| 108-88-3 |
|
2-Propanesulfonic acid sodium salt, mono- hydrate
| 5399-58-6 |
|
Acetonitrile, Anhydrous, 99.9%, 50ppm Water
| 75-05-8 |
|
Pyridine, anhydrous, 99.0%,< 50 ppm water
| 110-86-1 |
|
Benzene, Anhydrous, 99.0%, 50ppm Water
| 71-43-2 |
|
Methyl sulfoxide, anhydrous, SC, 99.7%, AcroSeal (TM)
| 67-68-5 |
|
Titanium (IV) Fluoride
| 7783-63-3 |
|
10X Tris-EDTA (pH 7.4 - 7.6) Solution
| 60-00-4 |
|
Omega-Undecylenyl Alcohol, 99%
| 112-43-6 |
|
trans-4-Phenyl-3-buten-2-one, 99%
| 1896-62-4 |
|
2-Decanol, 98%
| 1120-06-5 |
|
4-Cyanophenyl Isothiocyanate (Pract)
| 2719-32-6 |
|
Poly(2-acrylamido-2-methyl-1-propanesulfonic acid-co-acrylonitrile)
| 54640-82-3 |
|
2-Chloro-5-nitrobenzyl alcohol, 97%
| 80866-80-4 |
|
Methyl 4-Chlorobenzoylacetate
| |
|
0.5M Alcoholic potassium hydroxide solution
| 64-17-5 |
|
0.1M Alcoholic potassium hydroxide solution
| 64-17-5 |
|
Shellac Ester
| 0-01-1 |
|
Chloromethyl Ethyl Ether, contains ca. 12% Chloroethyl Methyl Ether,
| 3188-13-4 |
|
Water Standard 0.10-0.20 mg/g
| 1330-20-7 |
|
Aqualine Water Standard 0.2-1.0 mg/ml
| 100-66-3 |
|
Lithium metaborate, 99%
| 13453-69-5 |
|
Water Standard 10.0 mg./ml.
| 71-36-3 |
|
Water Standard 5.0 mg./ml.
| 71-36-3 |
|
Water Standard KF Oven
| 6100-05-6 |
|
|